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Gene: Cysltr1 (cysteinyl leukotriene receptor 1) Mus musculus
Symbol: Cysltr1
Name: cysteinyl leukotriene receptor 1
Description: Exhibits leukotriene receptor activity. Involved in several processes, including calcium ion transport; chemotaxis; and inflammatory response to antigenic stimulus. Localizes to the integral component of plasma membrane. Human ortholog(s) of this gene implicated in allergic hypersensitivity disease; asthma; and rhinitis. Is expressed in central nervous system and retina. Orthologous to human CYSLTR1 (cysteinyl leukotriene receptor 1); PARTICIPATES IN endothelin signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxynon-2-enal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BB147369; Cyslt1; CysLT1R; cysteinyl leukotriene 1 receptor; cysteinyl leukotriene 1 receptor short isoform; cysteinyl leukotriene D4 receptor; leukotriene D4 receptor; LTD4 receptor
Homo sapiens (human) : CYSLTR1 (cysteinyl leukotriene receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cysltr1 (cysteinyl leukotriene receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cysltr1 (cysteinyl leukotriene receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CYSLTR1 (cysteinyl leukotriene receptor 1)
Canis lupus familiaris (dog) : CYSLTR1 (cysteinyl leukotriene receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cysltr1 (cysteinyl leukotriene receptor 1)
Sus scrofa (pig) : CYSLTR1 (cysteinyl leukotriene receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38X106,576,509 - 106,603,679 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X103,771,856 - 103,798,801 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X102,779,236 - 102,806,181 (-)NCBImm8
CeleraX93,425,088 - 93,451,999 (-)NCBICelera
Cytogenetic MapX DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cysltr1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732525
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.