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Gene: Dkk3 (dickkopf WNT signaling pathway inhibitor 3) Mus musculus
Symbol: Dkk3
Name: dickkopf WNT signaling pathway inhibitor 3
Description: Predicted to have co-receptor binding activity and receptor antagonist activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway and negative regulation of cellular biosynthetic process. Localizes to extracellular space. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; eye; and limb. Orthologous to human DKK3 (dickkopf WNT signaling pathway inhibitor 3); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW061014; C87148; dickkopf homolog 3; dickkopf-3; dickkopf-related protein 3; dkk-3; mDkk-3
Homo sapiens (human) : DKK3 (dickkopf WNT signaling pathway inhibitor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dkk3 (dickkopf WNT signaling pathway inhibitor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dkk3 (dickkopf WNT signaling pathway inhibitor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DKK3 (dickkopf WNT signaling pathway inhibitor 3)
Canis lupus familiaris (dog) : DKK3 (dickkopf WNT signaling pathway inhibitor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dkk3 (dickkopf WNT signaling pathway inhibitor 3)
Sus scrofa (pig) : DKK3 (dickkopf WNT signaling pathway inhibitor 3)
Chlorocebus sabaeus (African green monkey) : DKK3 (dickkopf WNT signaling pathway inhibitor 3)
Heterocephalus glaber (naked mole-rat) : Dkk3 (dickkopf WNT signaling pathway inhibitor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl7112,116,017 - 112,159,057 (-)EnsemblGRCm38mm10GRCm38
GRCm387112,116,019 - 112,159,482 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377119,259,533 - 119,302,571 (-)NCBIGRCm37mm9NCBIm37
MGSCv367111,907,200 - 111,950,238 (-)NCBImm8
Celera7112,091,357 - 112,134,444 (-)NCBICelera
Cytogenetic Map7F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Dkk3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732521
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.