Dscam (DS cell adhesion molecule) - Rat Genome Database

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Gene: Dscam (DS cell adhesion molecule) Mus musculus
Analyze
Symbol: Dscam
Name: DS cell adhesion molecule
RGD ID: 732494
MGI Page MGI
Description: Enables netrin receptor binding activity and protein tyrosine kinase binding activity. Involved in several processes, including netrin-activated signaling pathway; neuron development; and positive regulation of axon extension involved in axon guidance. Acts upstream of or within dendrite morphogenesis; locomotory behavior; and post-embryonic retina morphogenesis in camera-type eye. Located in several cellular components, including dendrite; growth cone; and neuronal cell body. Is expressed in several structures, including central nervous system; peripheral nervous system; sensory organ; skin; and testis. Orthologous to human DSCAM (DS cell adhesion molecule).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4932410A21Rik; cell adhesion molecule DSCAM; Down syndrome cell adhesion molecule; Down syndrome cell adhesion molecule homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391696,388,652 - 96,971,935 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1696,392,040 - 96,971,952 (-)EnsemblGRCm39 Ensembl
GRCm381696,587,452 - 97,171,113 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1696,590,840 - 97,170,752 (-)EnsemblGRCm38mm10GRCm38
MGSCv371696,813,686 - 97,392,342 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361696,697,642 - 97,275,645 (-)NCBIMGSCv36mm8
Celera1697,670,177 - 98,230,565 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1657.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (IBA,IDA)
cell projection  (IEA)
dendrite  (IDA)
growth cone  (IDA)
membrane  (IEA)
neuronal cell body  (IBA,IDA)
plasma membrane  (IBA,IDA,TAS)
synapse  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal amacrine cell morphology  (IAGP)
abnormal axon fasciculation  (IAGP)
abnormal brain commissure morphology  (IAGP)
abnormal brain internal capsule morphology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal brain ventricle morphology  (IAGP)
abnormal breathing pattern  (IAGP)
abnormal central pattern generator function  (IAGP)
abnormal cerebellar foliation  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal corpus callosum morphology  (IAGP)
abnormal cranial cavity morphology  (IAGP)
abnormal dopaminergic neuron morphology  (IAGP)
abnormal eye electrophysiology  (IAGP)
abnormal gait  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal lateral ventricle morphology  (IAGP)
abnormal maternal behavior  (IAGP)
abnormal motor learning  (IAGP)
abnormal neurite morphology  (IAGP)
abnormal posture  (IAGP)
abnormal respiration  (IAGP)
abnormal resting posture  (IAGP)
abnormal retina bipolar cell morphology  (IAGP)
abnormal retina cone bipolar cell morphology  (IAGP)
abnormal retina ganglion cell morphology  (IAGP)
abnormal retina ganglion layer morphology  (IAGP)
abnormal retina inner nuclear layer morphology  (IAGP)
abnormal retina inner nuclear layer thickness  (IAGP)
abnormal retina inner plexiform layer morphology  (IAGP)
abnormal retina morphology  (IAGP)
abnormal retina neuronal layer morphology  (IAGP)
abnormal somatic nervous system physiology  (IAGP)
apnea  (IAGP)
decreased pulmonary respiratory rate  (IAGP)
decreased striatum size  (IAGP)
delayed eyelid opening  (IAGP)
delayed parturition  (IAGP)
dilated brain ventricle  (IAGP)
dilated third ventricle  (IAGP)
disorganized retina ganglion layer  (IAGP)
disorganized retina inner nuclear layer  (IAGP)
domed cranium  (IAGP)
enlarged brain ventricles  (IAGP)
enlarged cerebral aqueduct  (IAGP)
enlarged lateral ventricles  (IAGP)
hydrocephaly  (IAGP)
impaired balance  (IAGP)
impaired coordination  (IAGP)
impaired swimming  (IAGP)
increased amacrine cell number  (IAGP)
increased neuron number  (IAGP)
increased retina ganglion cell number  (IAGP)
kyphosis  (IAGP)
muscle hypertonia  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
respiratory distress  (IAGP)
retina hyperplasia  (IAGP)
seizures  (IAGP)
small ears  (IAGP)
small olfactory bulb  (IAGP)
thick retina ganglion layer  (IAGP)
thick retina inner plexiform layer  (IAGP)
thin cerebral cortex  (IAGP)
trunk curl  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Down syndrome cell adhesion molecule is conserved in mouse and highly expressed in the adult mouse brain. Barlow GM, etal., Cytogenet Cell Genet 2001;94(3-4):155-62.
2. Down syndrome congenital heart disease: a narrowed region and a candidate gene. Barlow GM, etal., Genet Med 2001 Mar-Apr;3(2):91-101.
3. A gene expression map of human chromosome 21 orthologues in the mouse. Gitton Y, etal., Nature 2002 Dec 5;420(6915):586-90.
4. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. Human chromosome 21 gene expression atlas in the mouse. Reymond A, etal., Nature 2002 Dec 5;420(6915):582-6.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. DSCAM: a novel member of the immunoglobulin superfamily maps in a Down syndrome region and is involved in the development of the nervous system. Yamakawa K, etal., Hum Mol Genet 1998 Feb;7(2):227-37.
Additional References at PubMed
PMID:8889548   PMID:9750193   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11237714   PMID:11374901   PMID:11749073   PMID:12051741   PMID:12435380   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:16987237   PMID:17582329   PMID:18216855   PMID:18585357   PMID:18799693   PMID:18948420   PMID:19196994   PMID:19261893   PMID:19945385   PMID:19945391   PMID:20217312  
PMID:20715164   PMID:20926679   PMID:21241773   PMID:21267068   PMID:21677750   PMID:21873635   PMID:21904980   PMID:22063212   PMID:22238077   PMID:22396220   PMID:22403711   PMID:22685302  
PMID:22726835   PMID:23175819   PMID:23300735   PMID:24477985   PMID:25352748   PMID:25451118   PMID:25754961   PMID:25826454   PMID:25855178   PMID:26633812   PMID:26633881   PMID:26655819  
PMID:26659141   PMID:26683069   PMID:26691152   PMID:26858598   PMID:26966010   PMID:27046121   PMID:27390513   PMID:27637097   PMID:28137836   PMID:28671696   PMID:29093169   PMID:29114051  
PMID:29718256   PMID:30297418   PMID:30998504   PMID:32325033   PMID:32562661   PMID:32917586   PMID:33585465   PMID:34253863   PMID:34321999   PMID:34848499   PMID:35914814   PMID:37079499  
PMID:38302444  


Genomics

Comparative Map Data
Dscam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391696,388,652 - 96,971,935 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1696,392,040 - 96,971,952 (-)EnsemblGRCm39 Ensembl
GRCm381696,587,452 - 97,171,113 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1696,590,840 - 97,170,752 (-)EnsemblGRCm38mm10GRCm38
MGSCv371696,813,686 - 97,392,342 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361696,697,642 - 97,275,645 (-)NCBIMGSCv36mm8
Celera1697,670,177 - 98,230,565 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1657.02NCBI
DSCAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382140,010,999 - 40,847,158 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2140,010,999 - 40,847,158 (-)EnsemblGRCh38hg38GRCh38
GRCh372141,382,926 - 42,219,084 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362140,306,213 - 41,140,909 (-)NCBINCBI36Build 36hg18NCBI36
Build 342140,306,212 - 41,140,909NCBI
Celera2126,582,079 - 27,417,510 (-)NCBICelera
Cytogenetic Map21q22.2NCBI
HuRef2126,884,190 - 27,191,292 (-)NCBIHuRef
HuRef2127,195,979 - 27,689,477 (-)NCBIHuRef
CHM1_12140,945,084 - 41,641,065 (-)NCBICHM1_1
T2T-CHM13v2.02138,398,213 - 39,235,595 (-)NCBIT2T-CHM13v2.0
Dscam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81149,391,385 - 49,976,861 (-)NCBIGRCr8
mRatBN7.21135,921,924 - 36,507,100 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,926,896 - 36,507,415 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1144,576,796 - 45,149,722 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01137,248,172 - 37,821,087 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01136,401,719 - 36,980,976 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01137,004,776 - 37,599,866 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1137,004,902 - 37,253,776 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01140,530,620 - 41,112,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41136,954,750 - 37,230,296 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11137,012,825 - 37,275,047 (-)NCBI
Celera1135,824,419 - 36,395,688 (-)NCBICelera
Cytogenetic Map11q11NCBI
Dscam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540739,986,108 - 40,473,200 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540739,985,501 - 40,473,330 (-)NCBIChiLan1.0ChiLan1.0
DSCAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22236,111,075 - 36,938,885 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12130,966,996 - 31,793,715 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02126,366,295 - 27,192,617 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12139,699,077 - 40,054,961 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2139,699,077 - 40,524,164 (-)Ensemblpanpan1.1panPan2
DSCAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13134,666,300 - 35,277,651 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3134,669,424 - 35,400,160 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3133,951,978 - 34,617,540 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03134,180,996 - 34,914,940 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3134,181,499 - 34,914,869 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13134,050,877 - 34,780,483 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03134,056,656 - 34,784,846 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03134,548,894 - 35,278,352 (-)NCBIUU_Cfam_GSD_1.0
Dscam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497134,128,713 - 34,780,976 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365002,686,850 - 3,338,498 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365002,686,847 - 3,339,110 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DSCAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13203,567,129 - 204,313,820 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113203,566,765 - 204,292,079 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213213,656,399 - 213,751,939 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DSCAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1283,969,555 - 84,738,661 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605411,797,452 - 12,609,644 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dscam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474528,969,498 - 29,559,968 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474528,969,464 - 29,560,557 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dscam
16760 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:254
Count of miRNA genes:219
Interacting mature miRNAs:222
Transcripts:ENSMUST00000056102
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141113Tgq28_mtriglyceride QTL 28 (mouse)Not determined6298664696986646Mouse
1300928Etia_methanol induced activation (mouse)Not determined166331390797314016Mouse
1558740Bpq9_mblood pressure QTL 9 (mouse)Not determined166332733697327472Mouse
1302194Pgia10_mproteoglycan induced arthritis 10 (mouse)Not determined166860072298008968Mouse
1301032Tauph_mtau phosphorylation (mouse)Not determined166907613298008968Mouse
11049573Lmr18b_mleishmaniasis resistance 18b (mouse)166912761198008968Mouse
11049574Lmr18a_mleishmaniasis resistance 18a (mouse)166912761198008968Mouse
4142262Lmr18_mleishmaniasis resistance 18 (mouse)Not determined166912761198008968Mouse
11522753Cocia19_mcocaine-induced activity, QTL 19 (mouse)166925448298008968Mouse
1301598Renf2_mrenal failure 2 (mouse)Not determined167038025298008968Mouse

Markers in Region
RH118366  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381696,899,294 - 96,899,467UniSTSGRCm38
MGSCv371697,120,901 - 97,121,074UniSTSGRCm37
Celera1645,390,063 - 45,390,236UniSTS
Cytogenetic Map16CUniSTS
Cytogenetic Map16B5UniSTS
cM Map1670.5UniSTS
Whitehead/MRC_RH161002.04UniSTS
Whitehead_YAC16 UniSTS
D16Mit71  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381696,913,248 - 96,913,401UniSTSGRCm38
MGSCv371697,134,855 - 97,135,008UniSTSGRCm37
Celera1697,973,464 - 97,973,623UniSTS
Cytogenetic Map16CUniSTS
cM Map1670.65UniSTS
Whitehead Genetic1651.4UniSTS
Whitehead_YAC16 UniSTS
G67847  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381696,655,650 - 96,655,872UniSTSGRCm38
MGSCv371696,877,257 - 96,877,479UniSTSGRCm37
Celera1697,734,075 - 97,734,297UniSTS
Cytogenetic Map16CUniSTS
cM Map16 UniSTS
G67848  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381696,721,928 - 96,722,096UniSTSGRCm38
MGSCv371696,943,535 - 96,943,703UniSTSGRCm37
Celera1697,803,638 - 97,803,806UniSTS
Cytogenetic Map16CUniSTS
cM Map16 UniSTS
G67849  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381696,845,642 - 96,845,852UniSTSGRCm38
MGSCv371697,067,249 - 97,067,459UniSTSGRCm37
Celera1697,924,048 - 97,924,258UniSTS
Cytogenetic Map16CUniSTS
cM Map16 UniSTS
G67850  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381696,858,314 - 96,858,613UniSTSGRCm38
MGSCv371697,079,921 - 97,080,220UniSTSGRCm37
Celera1697,936,737 - 97,937,036UniSTS
Cytogenetic Map16CUniSTS
cM Map16 UniSTS
G67851  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381696,874,364 - 96,874,577UniSTSGRCm38
MGSCv371697,095,971 - 97,096,184UniSTSGRCm37
Celera1645,414,907 - 45,415,120UniSTS
Cytogenetic Map16CUniSTS
Cytogenetic Map16B5UniSTS
cM Map16 UniSTS
G67852  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381696,961,689 - 96,961,926UniSTSGRCm38
MGSCv371697,183,296 - 97,183,533UniSTSGRCm37
Celera1698,021,903 - 98,022,140UniSTS
Cytogenetic Map16CUniSTS
cM Map16 UniSTS
Dscam  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381696,593,169 - 96,593,410UniSTSGRCm38
MGSCv371696,814,776 - 96,815,017UniSTSGRCm37
Celera1697,671,267 - 97,671,508UniSTS
Cytogenetic Map16CUniSTS
cM Map1670.5UniSTS
Dscam  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381696,592,998 - 96,593,400UniSTSGRCm38
MGSCv371696,814,605 - 96,815,007UniSTSGRCm37
Celera1697,671,096 - 97,671,498UniSTS
Cytogenetic Map16CUniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003951753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003951754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004939160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004939161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004939162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC154387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC156015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC167169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF315558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK016518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP004639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY005483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT030689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000056102   ⟹   ENSMUSP00000056040
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1696,392,040 - 96,971,952 (-)Ensembl
GRCm38.p6 Ensembl1696,590,840 - 97,170,752 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232829   ⟹   ENSMUSP00000156602
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1696,393,637 - 96,423,954 (-)Ensembl
GRCm38.p6 Ensembl1696,592,437 - 96,622,754 (-)Ensembl
RefSeq Acc Id: NM_031174   ⟹   NP_112451
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,393,279 - 96,971,935 (-)NCBI
GRCm381696,592,079 - 97,170,735 (-)NCBI
MGSCv371696,813,686 - 97,392,342 (-)RGD
Celera1697,670,177 - 98,230,565 (-)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006522886   ⟹   XP_006522949
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,388,652 - 96,971,600 (-)NCBI
GRCm381696,587,452 - 97,170,918 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006522887   ⟹   XP_006522950
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,392,225 - 96,971,522 (-)NCBI
GRCm381696,592,915 - 96,715,428 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248963   ⟹   XP_030104823
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,393,278 - 96,971,518 (-)NCBI
GRCm381696,592,915 - 96,833,493 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159771   ⟹   XP_036015664
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,393,283 - 96,971,564 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159772   ⟹   XP_036015665
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,392,225 - 96,971,518 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159773   ⟹   XP_036015666
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,393,279 - 96,971,554 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159774   ⟹   XP_036015667
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,393,279 - 96,971,518 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003951753
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,393,286 - 96,971,600 (-)NCBI
GRCm381696,629,368 - 97,170,954 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003951754
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,430,568 - 96,971,600 (-)NCBI
GRCm381696,673,712 - 97,171,113 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004939160
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,430,568 - 96,971,600 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004939161
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,430,568 - 96,971,600 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004939162
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391696,430,568 - 96,971,600 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_112451   ⟸   NM_031174
- Peptide Label: precursor
- UniProtKB: Q9ERC8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006522950   ⟸   XM_006522887
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006522949   ⟸   XM_006522886
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030104823   ⟸   XM_030248963
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000056040   ⟸   ENSMUST00000056102
RefSeq Acc Id: ENSMUSP00000156602   ⟸   ENSMUST00000232829
RefSeq Acc Id: XP_036015665   ⟸   XM_036159772
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036015666   ⟸   XM_036159773
- Peptide Label: isoform X5
RefSeq Acc Id: XP_036015667   ⟸   XM_036159774
- Peptide Label: isoform X5
RefSeq Acc Id: XP_036015664   ⟸   XM_036159771
- Peptide Label: isoform X3
Protein Domains
Fibronectin type-III   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ERC8-F1-model_v2 AlphaFold Q9ERC8 1-2013 view protein structure

Promoters
RGD ID:13674576
Promoter ID:EPDNEW_M21437
Type:initiation region
Name:Dscam_1
Description:Mus musculus DS cell adhesion molecule , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381697,170,828 - 97,170,888EPDNEW
RGD ID:6826985
Promoter ID:MM_KWN:21875
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_031174,   OTTMUST00000041364
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361697,392,986 - 97,393,486 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1196281 AgrOrtholog
Ensembl Genes ENSMUSG00000050272 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000056102 ENTREZGENE
  ENSMUST00000056102.9 UniProtKB/Swiss-Prot
  ENSMUST00000232829.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
KEGG Report mmu:13508 UniProtKB/Swiss-Prot
MGD MGI:1196281 ENTREZGENE
NCBI Gene 13508 ENTREZGENE
PANTHER DOWN SYNDROME CELL ADHESION MOLECULE UniProtKB/Swiss-Prot
  PTHR10075 UniProtKB/Swiss-Prot
Pfam fn3 UniProtKB/Swiss-Prot
  I-set UniProtKB/Swiss-Prot
  Ig_3 UniProtKB/Swiss-Prot
PhenoGen Dscam PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot
  IG_LIKE UniProtKB/Swiss-Prot
SMART FN3 UniProtKB/Swiss-Prot
  IGc2 UniProtKB/Swiss-Prot
  IGv UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
UniProt A0A3B2W3U6_MOUSE UniProtKB/TrEMBL
  DSCAM_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-21 Dscam  DS cell adhesion molecule    Down syndrome cell adhesion molecule  Symbol and/or name change 5135510 APPROVED