Ptpn12 (protein tyrosine phosphatase, non-receptor type 12) - Rat Genome Database

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Gene: Ptpn12 (protein tyrosine phosphatase, non-receptor type 12) Mus musculus
Analyze
Symbol: Ptpn12
Name: protein tyrosine phosphatase, non-receptor type 12
RGD ID: 732478
MGI Page MGI
Description: Enables phosphoprotein phosphatase activity. Acts upstream of or within protein dephosphorylation. Located in cytosol and podosome. Is expressed in several structures, including central nervous system; embryo mesenchyme; extraembryonic component; gut; and retina. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human PTPN12 (protein tyrosine phosphatase non-receptor type 12).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MPTP-PEST; P19-; P19-PTP; protein-tyrosine phosphatase P19; PTP-; PTP-P19; PTP-PEST; PTPG1; tyrosine-protein phosphatase non-receptor type 12
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39521,191,643 - 21,261,009 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl521,191,643 - 21,260,909 (-)EnsemblGRCm39 Ensembl
GRCm38520,986,645 - 21,055,911 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl520,986,645 - 21,055,911 (-)EnsemblGRCm38mm10GRCm38
MGSCv37520,492,463 - 20,561,615 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36520,498,469 - 20,567,621 (-)NCBIMGSCv36mm8
Celera517,944,646 - 18,014,696 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map59.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-butoxyethanol  (EXP)
3',5'-cyclic GMP  (ISO)
6-propyl-2-thiouracil  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
C60 fullerene  (ISO)
caffeine  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
flavonoids  (ISO)
folic acid  (EXP)
FR900359  (ISO)
geldanamycin  (ISO)
gentamycin  (ISO)
hypochlorous acid  (EXP)
indometacin  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
mercury dichloride  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
N(6)-dimethylallyladenine  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (EXP)
pirinixic acid  (EXP)
potassium chromate  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
tetrachloromethane  (EXP)
thimerosal  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zinc protoporphyrin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell projection  (IEA)
cytoplasm  (IBA)
cytosol  (IDA)
focal adhesion  (IEA)
nucleus  (IBA)
podosome  (IDA)

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1472029   PMID:1590786   PMID:1932742   PMID:7490087   PMID:7772023   PMID:7838537   PMID:8626541   PMID:8875997   PMID:9804817   PMID:10092676   PMID:10349636   PMID:11042159  
PMID:11076861   PMID:11217851   PMID:11711533   PMID:11832424   PMID:12052829   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12674328   PMID:12904583   PMID:14610273   PMID:14699151  
PMID:14707117   PMID:15226823   PMID:15345747   PMID:15782199   PMID:15786712   PMID:16141072   PMID:16141073   PMID:16204241   PMID:16317044   PMID:16670297   PMID:17070019   PMID:17130234  
PMID:18457880   PMID:19350555   PMID:19595712   PMID:19727691   PMID:19930043   PMID:20075861   PMID:20697350   PMID:20727793   PMID:21873635   PMID:22342188   PMID:23105101   PMID:23296707  
PMID:23589331   PMID:23897807   PMID:24366546   PMID:25666508   PMID:26391955   PMID:27626380   PMID:28808245   PMID:34050187   PMID:34321999   PMID:35449600   PMID:38355793  


Genomics

Comparative Map Data
Ptpn12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39521,191,643 - 21,261,009 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl521,191,643 - 21,260,909 (-)EnsemblGRCm39 Ensembl
GRCm38520,986,645 - 21,055,911 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl520,986,645 - 21,055,911 (-)EnsemblGRCm38mm10GRCm38
MGSCv37520,492,463 - 20,561,615 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36520,498,469 - 20,567,621 (-)NCBIMGSCv36mm8
Celera517,944,646 - 18,014,696 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map59.83NCBI
PTPN12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38777,537,295 - 77,640,069 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl777,537,295 - 77,640,069 (+)EnsemblGRCh38hg38GRCh38
GRCh37777,166,612 - 77,269,386 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36777,004,771 - 77,107,322 (+)NCBINCBI36Build 36hg18NCBI36
Build 34776,811,485 - 76,914,037NCBI
Celera771,867,421 - 71,970,039 (+)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef771,768,818 - 71,871,494 (+)NCBIHuRef
CHM1_1777,097,083 - 77,199,758 (+)NCBICHM1_1
T2T-CHM13v2.0778,789,201 - 78,891,996 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2776,499,836 - 76,602,451 (+)NCBI
Ptpn12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8414,913,071 - 14,985,084 (+)NCBIGRCr8
mRatBN7.2414,020,997 - 14,092,931 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl414,021,052 - 14,092,927 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx419,158,307 - 19,230,084 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0414,960,328 - 15,032,112 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0413,343,956 - 13,415,737 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0410,631,129 - 10,702,390 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl410,631,073 - 10,702,386 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0410,623,632 - 10,695,128 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.449,517,642 - 9,589,954 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.149,517,585 - 9,574,832 (+)NCBI
Celera49,582,368 - 9,654,126 (+)NCBICelera
Cytogenetic Map4q11NCBI
Ptpn12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554107,557,103 - 7,599,139 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554107,556,283 - 7,599,170 (-)NCBIChiLan1.0ChiLan1.0
PTPN12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2695,387,345 - 95,490,209 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17143,651,984 - 143,754,849 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0769,457,158 - 69,560,111 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1783,268,834 - 83,371,120 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl783,268,834 - 83,371,120 (+)Ensemblpanpan1.1panPan2
PTPN12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11817,608,665 - 17,692,543 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1817,607,936 - 17,692,219 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1817,266,233 - 17,315,593 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01817,927,205 - 18,011,994 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1817,927,265 - 18,011,993 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11817,677,847 - 17,762,567 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01817,617,247 - 17,702,020 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01817,886,436 - 17,971,250 (+)NCBIUU_Cfam_GSD_1.0
Ptpn12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511859,785,782 - 59,892,793 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647920,909,551 - 21,016,606 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647920,909,557 - 21,016,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPN12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9102,480,924 - 102,563,751 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19102,480,914 - 102,563,969 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29112,920,939 - 112,961,308 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPN12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12171,285,917 - 71,389,645 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2171,285,736 - 71,389,926 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604232,533,869 - 32,637,803 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptpn12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473926,747,830 - 26,828,535 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:718
Count of miRNA genes:473
Interacting mature miRNAs:537
Transcripts:ENSMUST00000030556, ENSMUST00000126853, ENSMUST00000140057, ENSMUST00000148711, ENSMUST00000151366, ENSMUST00000151813
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301685Estq2_mestradiol regulated response QTL 2 (mouse)Not determined51563408449634190Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5812411742124239Mouse
7394748Mom5_mmodifier of Min 5 (mouse)Not determined5884767233475637Mouse
4141234Pbwg14_mpostnatal body weight growth 14 (mouse)Not determined5121273552Mouse
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5350482337504823Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
1301468Eye1_meye weight 1 (mouse)Not determined5121929650Mouse
10412081Bwq13_mbody weight QTL 13 (mouse)Not determined5123606323Mouse
1357478Kdnw1_mkidney weight 1 (mouse)Not determined5891594940529869Mouse
13432187Actdse1_mactivity chamber total difference saline/ethanol 1 (mouse)51819918023099180Mouse
12904958Gmmq8_mgastrocnemius muscle mass QTL 8 (mouse)5129421124Mouse
14696730Kidlq1_mkidney weight, left QTL 1 (mouse)51356315247563152Mouse
10401122Pgia41_mproteoglycan induced arthritis 41 (mouse)Not determined582314434823280Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52068699354687134Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5538452039384652Mouse

Markers in Region
BB070754  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38521,025,319 - 21,025,406UniSTSGRCm38
GRCm38254,981,426 - 54,981,513UniSTSGRCm38
MGSCv37520,531,137 - 20,531,224UniSTSGRCm37
MGSCv37254,833,837 - 54,833,924UniSTSGRCm37
Celera517,983,320 - 17,983,407UniSTS
Celera256,742,484 - 56,742,571UniSTS
Cytogenetic Map2C1.1UniSTS
Cytogenetic Map5A3-BUniSTS
Whitehead/MRC_RH5218.96UniSTS
PTPN12_1837  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38520,986,867 - 20,987,487UniSTSGRCm38
MGSCv37520,492,685 - 20,493,305UniSTSGRCm37
Celera517,944,868 - 17,945,488UniSTS
Cytogenetic Map5A3-BUniSTS
Ptpn12  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5A3-BUniSTS
cM Map5 UniSTS
Ptpn12  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5A3-BUniSTS
cM Map5 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001356590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001356591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001356592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001424519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001424521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004942460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004942461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC116501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC121572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC140921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ092526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X63440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X86781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000030556   ⟹   ENSMUSP00000030556
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl521,191,643 - 21,260,909 (-)Ensembl
GRCm38.p6 Ensembl520,986,645 - 21,055,911 (-)Ensembl
Ensembl Acc Id: ENSMUST00000126853
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl521,203,451 - 21,214,604 (-)Ensembl
GRCm38.p6 Ensembl520,998,453 - 21,009,606 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140057   ⟹   ENSMUSP00000117697
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl521,214,442 - 21,260,723 (-)Ensembl
GRCm38.p6 Ensembl521,009,444 - 21,055,725 (-)Ensembl
Ensembl Acc Id: ENSMUST00000148711
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl521,203,277 - 21,206,409 (-)Ensembl
GRCm38.p6 Ensembl520,998,279 - 21,001,411 (-)Ensembl
Ensembl Acc Id: ENSMUST00000151366
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl521,191,644 - 21,194,259 (-)Ensembl
GRCm38.p6 Ensembl520,986,646 - 20,989,261 (-)Ensembl
Ensembl Acc Id: ENSMUST00000151813   ⟹   ENSMUSP00000116989
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl521,206,286 - 21,260,751 (-)Ensembl
GRCm38.p6 Ensembl521,001,288 - 21,055,753 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199774   ⟹   ENSMUSP00000142550
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl521,210,360 - 21,260,895 (-)Ensembl
GRCm38.p6 Ensembl521,005,362 - 21,055,897 (-)Ensembl
RefSeq Acc Id: NM_001356590   ⟹   NP_001343519
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,240,245 (-)NCBI
GRCm38520,986,645 - 21,035,247 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001356591   ⟹   NP_001343520
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,261,009 (-)NCBI
GRCm38520,986,645 - 21,055,911 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001356592   ⟹   NP_001343521
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,240,245 (-)NCBI
GRCm38520,986,645 - 21,035,247 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001424519   ⟹   NP_001411448
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,261,009 (-)NCBI
RefSeq Acc Id: NM_001424521   ⟹   NP_001411450
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,261,009 (-)NCBI
RefSeq Acc Id: NM_011203   ⟹   NP_035333
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,261,009 (-)NCBI
GRCm38520,986,645 - 21,055,911 (-)NCBI
MGSCv37520,492,463 - 20,561,615 (-)RGD
Celera517,944,646 - 18,014,696 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030254217   ⟹   XP_030110077
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,241,484 (-)NCBI
GRCm38520,986,645 - 21,031,462 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164911   ⟹   XP_036020804
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,241,484 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164912   ⟹   XP_036020805
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,241,484 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164913   ⟹   XP_036020806
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,241,484 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164914   ⟹   XP_036020807
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,241,484 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164915   ⟹   XP_036020808
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,241,484 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004942460
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,241,484 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004942461
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39521,191,643 - 21,241,484 (-)NCBI
Sequence:
RefSeq Acc Id: NP_035333   ⟸   NM_011203
- Peptide Label: isoform b
- UniProtKB: Q80UM4 (UniProtKB/Swiss-Prot),   P35831 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001343520   ⟸   NM_001356591
- Peptide Label: isoform c
RefSeq Acc Id: NP_001343521   ⟸   NM_001356592
- Peptide Label: isoform c
RefSeq Acc Id: NP_001343519   ⟸   NM_001356590
- Peptide Label: isoform a precursor
RefSeq Acc Id: XP_030110077   ⟸   XM_030254217
- Peptide Label: isoform X3
Ensembl Acc Id: ENSMUSP00000116989   ⟸   ENSMUST00000151813
Ensembl Acc Id: ENSMUSP00000142550   ⟸   ENSMUST00000199774
Ensembl Acc Id: ENSMUSP00000117697   ⟸   ENSMUST00000140057
Ensembl Acc Id: ENSMUSP00000030556   ⟸   ENSMUST00000030556
RefSeq Acc Id: XP_036020807   ⟸   XM_036164914
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036020808   ⟸   XM_036164915
- Peptide Label: isoform X5
RefSeq Acc Id: XP_036020805   ⟸   XM_036164912
- Peptide Label: isoform X2
RefSeq Acc Id: XP_036020804   ⟸   XM_036164911
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036020806   ⟸   XM_036164913
- Peptide Label: isoform X3
RefSeq Acc Id: NP_001411450   ⟸   NM_001424521
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001411448   ⟸   NM_001424519
- Peptide Label: isoform 4
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35831-F1-model_v2 AlphaFold P35831 1-775 view protein structure

Promoters
RGD ID:6838157
Promoter ID:MM_KWN:41482
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000073786,   OTTMUST00000073787,   OTTMUST00000073788
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36520,561,396 - 20,562,317 (-)MPROMDB
RGD ID:6886056
Promoter ID:EPDNEW_M6479
Type:initiation region
Name:Ptpn12_1
Description:Mus musculus protein tyrosine phosphatase, non-receptor type12 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38521,055,888 - 21,055,948EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104673 AgrOrtholog
Ensembl Genes ENSMUSG00000028771 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000030556 ENTREZGENE
  ENSMUST00000030556.8 UniProtKB/Swiss-Prot
  ENSMUST00000140057.2 UniProtKB/TrEMBL
  ENSMUST00000151813.8 UniProtKB/TrEMBL
  ENSMUST00000199774.5 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/Swiss-Prot
InterPro Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot
  PTN12/18/22 UniProtKB/Swiss-Prot
  PTN12_cat UniProtKB/Swiss-Prot
  PTPase_domain UniProtKB/Swiss-Prot
  Ptpn_12 UniProtKB/Swiss-Prot
  Tyr_Pase_AS UniProtKB/Swiss-Prot
  Tyr_Pase_cat UniProtKB/Swiss-Prot
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot
KEGG Report mmu:19248 UniProtKB/Swiss-Prot
MGD MGI:104673 ENTREZGENE
NCBI Gene 19248 ENTREZGENE
PANTHER TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED UniProtKB/Swiss-Prot
  TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 12 UniProtKB/Swiss-Prot
Pfam Y_phosphatase UniProtKB/Swiss-Prot
PhenoGen Ptpn12 PhenoGen
PIRSF Tyr-Ptase_nr12 UniProtKB/Swiss-Prot
PRINTS PRTYPHPHTASE UniProtKB/Swiss-Prot
PROSITE TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot
  TYR_PHOSPHATASE_PTP UniProtKB/Swiss-Prot
SMART PTPc UniProtKB/Swiss-Prot
  PTPc_motif UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52799 UniProtKB/Swiss-Prot
UniProt D6RGT2_MOUSE UniProtKB/TrEMBL
  F6Z0X5_MOUSE UniProtKB/TrEMBL
  P35831 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3TVC3_MOUSE UniProtKB/TrEMBL
  Q80UM4 ENTREZGENE
UniProt Secondary Q80UM4 UniProtKB/Swiss-Prot