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Gene: RASA1 (RAS p21 protein activator 1) Homo sapiens
Symbol: RASA1
Name: RAS p21 protein activator 1
Description: Exhibits several functions, including GTPase activator activity; GTPase binding activity; and phosphotyrosine residue binding activity. Involved in several processes, including blood vessel morphogenesis; negative regulation of cell-matrix adhesion; and regulation of actin filament polymerization. Predicted to localize to cytosol. Implicated in arteriovenous malformation and basal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CM-AVM; CMAVM; CMAVM1; DKFZp434N071; GAP; GTPase-activating protein; p120; p120GAP; p120RASGAP; PKWS; ras GTPase-activating protein 1; RAS p21 protein activator (GTPase activating protein) 1; RASA; RASGAP; triphosphatase-activating protein
Mus musculus (house mouse) : Rasa1 (RAS p21 protein activator 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rasa1 (RAS p21 protein activator 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rasa1 (RAS p21 protein activator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RASA1 (RAS p21 protein activator 1)
Canis lupus familiaris (dog) : RASA1 (RAS p21 protein activator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rasa1 (RAS p21 protein activator 1)
Sus scrofa (pig) : RASA1 (RAS p21 protein activator 1)
Chlorocebus sabaeus (African green monkey) : RASA1 (RAS p21 protein activator 1)
Heterocephalus glaber (naked mole-rat) : Rasa1 (RAS p21 protein activator 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl587,267,883 - 87,391,931 (+)EnsemblGRCh38hg38GRCh38
GRCh38587,267,845 - 87,391,926 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37586,564,070 - 86,687,743 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36586,599,907 - 86,723,489 (+)NCBINCBI36hg18NCBI36
Build 34586,600,521 - 86,723,488NCBI
Celera582,456,373 - 82,579,983 (+)NCBI
Cytogenetic Map5q14.3NCBI
HuRef581,768,403 - 81,891,908 (+)NCBIHuRef
CHM1_1585,997,132 - 86,120,771 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RASA1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732468
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.