Rpe65 (retinal pigment epithelium 65) - Rat Genome Database

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Gene: Rpe65 (retinal pigment epithelium 65) Mus musculus
Analyze
Symbol: Rpe65
Name: retinal pigment epithelium 65
RGD ID: 732417
MGI Page MGI
Description: Predicted to enable beta-carotene 15,15'-dioxygenase activity; carboxylic ester hydrolase activity; and retinol isomerase activity. Predicted to be involved in several processes, including detection of light stimulus involved in visual perception; retina homeostasis; and terpenoid metabolic process. Predicted to act upstream of or within lipid metabolic process and visual perception. Located in cytoplasm; nucleus; and plasma membrane. Is expressed in eye and urinary system. Used to study Leber congenital amaurosis 2 and retinitis pigmentosa 20. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 2; retinitis pigmentosa; retinitis pigmentosa 20; and retinitis pigmentosa 87. Orthologous to human RPE65 (retinoid isomerohydrolase RPE65).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 65kDa; A930029L06Rik; all-trans-retinyl-palmitate hydrolase; LCA2; lutein isomerase; meso-zeaxanthin isomerase; modifier of retinal degeneration 1; Mor; Mord1; rd1; rd12; retinal pigment epithelium, 65 kDa; retinal pigment epithelium-specific 65 kDa protein; retinoid isomerohydrolase; retinol isomerase; RP20
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393159,304,712 - 159,330,944 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3159,304,812 - 159,330,958 (+)EnsemblGRCm39 Ensembl
GRCm383159,599,075 - 159,625,307 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3159,599,175 - 159,625,321 (+)EnsemblGRCm38mm10GRCm38
MGSCv373159,262,145 - 159,288,271 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363159,534,526 - 159,560,092 (+)NCBIMGSCv36mm8
Celera3166,038,618 - 166,064,587 (+)NCBICelera
Cytogenetic Map3H4NCBI
cM Map382.52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement. Bowne SJ, etal., Eur J Hum Genet. 2011 Oct;19(10):1074-81. doi: 10.1038/ejhg.2011.86. Epub 2011 Jun 8.
2. RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice. Chen Y, etal., Invest Ophthalmol Vis Sci. 2006 Mar;47(3):1177-84.
3. Genes and mutations causing retinitis pigmentosa. Daiger SP, etal., Clin Genet. 2013 Aug;84(2):132-41. doi: 10.1111/cge.12203. Epub 2013 Jun 19.
4. Expression of RPE65, a putative receptor for plasma retinol-binding protein, in nonmelanocytic skin tumours. Hinterhuber G, etal., Br J Dermatol. 2005 Oct;153(4):785-9.
5. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. Retinal gene expression and visually evoked behavior in diabetic long evans rats. Kirwin SJ, etal., Invest Ophthalmol Vis Sci. 2011 Sep 29;52(10):7654-63. doi: 10.1167/iovs.10-6609.
7. Key enzymes of the retinoid (visual) cycle in vertebrate retina. Kiser PD, etal., Biochim Biophys Acta. 2012 Jan;1821(1):137-51. Epub 2011 Apr 5.
8. Alpha-phenyl-N-tert-butylnitrone (PBN) prevents light-induced degeneration of the retina by inhibiting RPE65 protein isomerohydrolase activity. Mandal MN, etal., J Biol Chem. 2011 Sep 16;286(37):32491-501. Epub 2011 Jul 24.
9. MGDs mouse GO annotations MGD data from the GO Consortium
10. MGD IEA MGD IEA
11. Experimental autoimmune uveitis induced by immunization with retinal pigment epithelium-specific 65-kDa protein peptides. Nakamura H, etal., Curr Eye Res. 2005 Aug;30(8):673-80.
12. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
15. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
16. Mouse MP Annotation Import Pipeline RGD automated import pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal. Samardzija M, etal., Hum Mol Genet. 2008 Jan 15;17(2):281-92. Epub 2007 Oct 12.
20. Transplantation of reprogrammed embryonic stem cells improves visual function in a mouse model for retinitis pigmentosa. Wang NK, etal., Transplantation. 2010 Apr 27;89(8):911-9. doi: 10.1097/TP.0b013e3181d45a61.
21. Spontaneous activity of opsin apoprotein is a cause of Leber congenital amaurosis. Woodruff ML, etal., Nat Genet 2003 Oct;35(2):158-64. Epub 2003 Sep 21.
22. Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait. Wright AF, etal., Nat Rev Genet. 2010 Apr;11(4):273-84. doi: 10.1038/nrg2717.
23. The Rpe65 rd12 allele exerts a semidominant negative effect on vision in mice. Wright CB, etal., Invest Ophthalmol Vis Sci. 2014 Apr 17;55(4):2500-15. doi: 10.1167/iovs.13-13574.
Additional References at PubMed
PMID:7544156   PMID:8034329   PMID:8910519   PMID:9193722   PMID:9843205   PMID:9858320   PMID:9935163   PMID:10349636   PMID:10556429   PMID:10773668   PMID:10777702   PMID:10802658  
PMID:10818205   PMID:10869443   PMID:10896939   PMID:11042159   PMID:11076861   PMID:11150319   PMID:11483174   PMID:11528395   PMID:11687551   PMID:11740468   PMID:11897783   PMID:11980880  
PMID:12176991   PMID:12356839   PMID:12477932   PMID:12506090   PMID:12590612   PMID:12657577   PMID:12716426   PMID:12716919   PMID:12766089   PMID:12954412   PMID:14532273   PMID:14550405  
PMID:14578454   PMID:14681479   PMID:14684738   PMID:14742273   PMID:15037595   PMID:15112105   PMID:15215287   PMID:15277666   PMID:15378383   PMID:15722110   PMID:15765048   PMID:15790918  
PMID:15837919   PMID:15961402   PMID:16014418   PMID:16026160   PMID:16043837   PMID:16110338   PMID:16141072   PMID:16141073   PMID:16186377   PMID:16332269   PMID:16519667   PMID:16553465  
PMID:16566595   PMID:16714237   PMID:16788070   PMID:16788071   PMID:16952355   PMID:16966486   PMID:17012256   PMID:17032058   PMID:17122101   PMID:17130236   PMID:17249562   PMID:17251447  
PMID:17272282   PMID:17504753   PMID:17960118   PMID:18188932   PMID:18195010   PMID:18296659   PMID:18326732   PMID:18326740   PMID:18400900   PMID:18474598   PMID:18483210   PMID:18515598  
PMID:18606814   PMID:18644591   PMID:18695249   PMID:18815272   PMID:18987202   PMID:19050768   PMID:19060264   PMID:19136713   PMID:19147682   PMID:19193895   PMID:19264891   PMID:19339306  
PMID:19407008   PMID:19407011   PMID:19438210   PMID:19470639   PMID:19478335   PMID:19494204   PMID:19506076   PMID:19544586   PMID:19661229   PMID:19672311   PMID:19737879   PMID:19834036  
PMID:19948961   PMID:20007830   PMID:20061388   PMID:20164334   PMID:20207741   PMID:20345762   PMID:20356843   PMID:20398652   PMID:20484585   PMID:20510285   PMID:20574023   PMID:20702833  
PMID:20876139   PMID:21052544   PMID:21076393   PMID:21169527   PMID:21224384   PMID:21228385   PMID:21267068   PMID:21304899   PMID:21430170   PMID:21447692   PMID:21464132   PMID:21493626  
PMID:21551411   PMID:21613504   PMID:21633714   PMID:21715356   PMID:21753017   PMID:21873635   PMID:21901134   PMID:22039245   PMID:22128240   PMID:22227450   PMID:22570475   PMID:22621924  
PMID:22745121   PMID:22786896   PMID:22855808   PMID:22886305   PMID:22953002   PMID:23009755   PMID:23143414   PMID:23249702   PMID:23274583   PMID:23274584   PMID:23341467   PMID:23383327  
PMID:23716657   PMID:23734084   PMID:23778877   PMID:23903667   PMID:24012986   PMID:24129572   PMID:24211856   PMID:24265546   PMID:24550448   PMID:24576873   PMID:24644405   PMID:24801306  
PMID:24849605   PMID:24952647   PMID:25015357   PMID:25034607   PMID:25392995   PMID:25593512   PMID:25706871   PMID:25972377   PMID:26062936   PMID:26387748   PMID:26392743   PMID:26400086  
PMID:26404741   PMID:26405179   PMID:26583326   PMID:26656104   PMID:26670830   PMID:26876013   PMID:27008858   PMID:27026593   PMID:27116862   PMID:27150101   PMID:27225770   PMID:27274068  
PMID:27391439   PMID:27503804   PMID:27623928   PMID:27768794   PMID:28041994   PMID:28143742   PMID:28348233   PMID:28395299   PMID:28428265   PMID:28500718   PMID:28889993   PMID:29038159  
PMID:29078372   PMID:29109151   PMID:29293603   PMID:29401616   PMID:29514656   PMID:29560458   PMID:29596840   PMID:29659842   PMID:29684583   PMID:29773803   PMID:29847651   PMID:29871924  
PMID:29874126   PMID:30042155   PMID:30115683   PMID:30185665   PMID:30242264   PMID:30352873   PMID:30446775   PMID:30459230   PMID:30566624   PMID:30628748   PMID:30695025   PMID:30850344  
PMID:31181196   PMID:31291592   PMID:31316114   PMID:31562844   PMID:31692906   PMID:31695081   PMID:31925423   PMID:31949211   PMID:31978605   PMID:32188692   PMID:32290105   PMID:32841098  
PMID:32958638   PMID:33257550   PMID:33299105   PMID:33479377   PMID:33614628   PMID:33784255   PMID:33795534   PMID:34582935   PMID:34677125   PMID:34847075   PMID:35271391   PMID:35383196  
PMID:37014074   PMID:37252956   PMID:37440066   PMID:37585292   PMID:37659708  


Genomics

Comparative Map Data
Rpe65
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393159,304,712 - 159,330,944 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3159,304,812 - 159,330,958 (+)EnsemblGRCm39 Ensembl
GRCm383159,599,075 - 159,625,307 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3159,599,175 - 159,625,321 (+)EnsemblGRCm38mm10GRCm38
MGSCv373159,262,145 - 159,288,271 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363159,534,526 - 159,560,092 (+)NCBIMGSCv36mm8
Celera3166,038,618 - 166,064,587 (+)NCBICelera
Cytogenetic Map3H4NCBI
cM Map382.52NCBI
RPE65
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38168,428,822 - 68,449,954 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl168,428,822 - 68,449,954 (-)EnsemblGRCh38hg38GRCh38
GRCh37168,894,505 - 68,915,637 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36168,667,095 - 68,688,230 (-)NCBINCBI36Build 36hg18NCBI36
Build 34168,606,465 - 68,627,663NCBI
Celera167,184,748 - 67,205,854 (-)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef167,004,313 - 67,025,452 (-)NCBIHuRef
CHM1_1169,009,866 - 69,031,001 (-)NCBICHM1_1
T2T-CHM13v2.0168,306,207 - 68,327,339 (-)NCBIT2T-CHM13v2.0
Rpe65
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82251,425,228 - 251,457,209 (+)NCBIGRCr8
mRatBN7.22248,766,497 - 248,798,403 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2248,766,612 - 248,798,403 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2256,482,408 - 256,514,178 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02254,375,936 - 254,407,703 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02249,342,889 - 249,374,020 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02266,141,581 - 266,169,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2266,141,581 - 266,169,197 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02284,774,159 - 284,804,254 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.12257,860,998 - 257,893,921 (+)NCBI
Celera2240,512,281 - 240,537,640 (+)NCBICelera
Cytogenetic Map2q45NCBI
Rpe65
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542323,183,937 - 23,208,282 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542323,184,326 - 23,208,206 (+)NCBIChiLan1.0ChiLan1.0
RPE65
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21158,421,347 - 158,442,454 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11157,581,121 - 157,602,228 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0167,666,784 - 67,687,891 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1169,623,775 - 69,644,894 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl169,623,775 - 69,644,904 (-)Ensemblpanpan1.1panPan2
RPE65
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1676,887,399 - 76,911,133 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl676,887,399 - 76,911,131 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha679,498,666 - 79,521,615 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0677,481,101 - 77,504,927 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl677,481,101 - 77,504,925 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1677,031,835 - 77,055,739 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0676,935,191 - 76,959,205 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0677,422,281 - 77,446,314 (+)NCBIUU_Cfam_GSD_1.0
Rpe65
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505881,055,133 - 81,142,276 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365913,347,272 - 3,368,015 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365913,347,346 - 3,368,062 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPE65
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6144,206,078 - 144,229,467 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16144,206,078 - 144,229,471 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26133,491,901 - 133,514,217 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPE65
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12064,662,777 - 64,684,178 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2064,664,358 - 64,683,211 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603352,929,980 - 52,950,761 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rpe65
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474227,302,453 - 27,319,203 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474227,302,222 - 27,319,549 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rpe65
682 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:72
Interacting mature miRNAs:75
Transcripts:ENSMUST00000029824
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142245Pstc1_mperiosteal circumference 1 (mouse)Not determined3126270248159745316Mouse
1301218Letohc1_mlow ethanol consumption 1 (mouse)Not determined3126352986159745316Mouse
1301347Fpli_mfasting plasma insulin (mouse)Not determined3126460514159745316Mouse
1301563Alcp3_malcohol preference locus 3 (mouse)Not determined3130736935159745316Mouse
11039523Tbbr1_mTrypanosoma brucei brucei response 1 (mouse)3130849375159745316Mouse
1301528Loco1_mlocomotor activity 1 (mouse)Not determined3133461893159745316Mouse

Markers in Region
Rpe65  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383159,603,347 - 159,603,766UniSTSGRCm38
MGSCv373159,266,311 - 159,266,730UniSTSGRCm37
Celera3166,042,769 - 166,043,183UniSTS
Cytogenetic Map3H4UniSTS
cM Map387.6UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000029824   ⟹   ENSMUSP00000029824
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3159,304,870 - 159,330,436 (+)Ensembl
GRCm38.p6 Ensembl3159,599,233 - 159,624,799 (+)Ensembl
RefSeq Acc Id: ENSMUST00000196999   ⟹   ENSMUSP00000143654
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3159,304,812 - 159,330,958 (+)Ensembl
GRCm38.p6 Ensembl3159,599,175 - 159,625,321 (+)Ensembl
RefSeq Acc Id: ENSMUST00000197771   ⟹   ENSMUSP00000143390
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3159,304,855 - 159,312,056 (+)Ensembl
GRCm38.p6 Ensembl3159,599,218 - 159,606,419 (+)Ensembl
RefSeq Acc Id: NM_029987   ⟹   NP_084263
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393159,304,818 - 159,330,944 (+)NCBI
GRCm383159,599,181 - 159,625,307 (+)NCBI
MGSCv373159,262,145 - 159,288,271 (+)RGD
Celera3166,038,618 - 166,064,587 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006501165   ⟹   XP_006501228
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393159,304,712 - 159,330,927 (+)NCBI
GRCm383159,599,075 - 159,625,290 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001783668
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393159,304,712 - 159,330,927 (+)NCBI
GRCm383159,599,075 - 159,625,290 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_084263   ⟸   NM_029987
- UniProtKB: H9KUX9 (UniProtKB/Swiss-Prot),   E9QNS6 (UniProtKB/Swiss-Prot),   A1L3D1 (UniProtKB/Swiss-Prot),   Q8VHP2 (UniProtKB/Swiss-Prot),   Q91ZQ5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006501228   ⟸   XM_006501165
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000143390   ⟸   ENSMUST00000197771
RefSeq Acc Id: ENSMUSP00000029824   ⟸   ENSMUST00000029824
RefSeq Acc Id: ENSMUSP00000143654   ⟸   ENSMUST00000196999

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q91ZQ5-F1-model_v2 AlphaFold Q91ZQ5 1-533 view protein structure

Promoters
RGD ID:6882716
Promoter ID:EPDNEW_M4808
Type:multiple initiation site
Name:Rpe65_1
Description:Mus musculus retinal pigment epithelium 65 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383159,599,186 - 159,599,246EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98001 AgrOrtholog
Ensembl Genes ENSMUSG00000028174 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000029824.9 UniProtKB/Swiss-Prot
  ENSMUST00000196999 ENTREZGENE
  ENSMUST00000196999.5 UniProtKB/Swiss-Prot
  ENSMUST00000197771.5 UniProtKB/TrEMBL
InterPro Carotenoid_Oase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19892 UniProtKB/Swiss-Prot
MGD MGI:98001 ENTREZGENE
NCBI Gene 19892 ENTREZGENE
PANTHER PTHR10543 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RETINOID ISOMEROHYDROLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RPE65 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rpe65 PhenoGen
UniProt A0A0G2JG19_MOUSE UniProtKB/TrEMBL
  A1L3D1 ENTREZGENE
  E9QNS6 ENTREZGENE
  H9KUX9 ENTREZGENE
  Q8VHP2 ENTREZGENE
  Q91ZQ5 ENTREZGENE
  Q9CTP3_MOUSE UniProtKB/TrEMBL
  RPE65_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary A1L3D1 UniProtKB/Swiss-Prot
  E9QNS6 UniProtKB/Swiss-Prot
  H9KUX9 UniProtKB/Swiss-Prot
  Q8VHP2 UniProtKB/Swiss-Prot