Myh9 (myosin, heavy polypeptide 9, non-muscle) - Rat Genome Database

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Gene: Myh9 (myosin, heavy polypeptide 9, non-muscle) Mus musculus
Analyze
Symbol: Myh9
Name: myosin, heavy polypeptide 9, non-muscle
RGD ID: 732402
MGI Page MGI
Description: Enables protein domain specific binding activity. Involved in several processes, including cortical granule exocytosis; negative regulation of actin filament severing; and positive regulation of protein processing in phagocytic vesicle. Acts upstream of or within several processes, including establishment of T cell polarity; microtubule cytoskeleton organization; and myoblast fusion. Located in several cellular components, including cortical granule; cytoskeleton; and immunological synapse. Part of myosin II complex. Colocalizes with focal adhesion. Is expressed in several structures, including alimentary system; early embryo; heart and pericardium; salivary gland primordium; and sensory organ. Used to study MYH-9 related disease. Human ortholog(s) of this gene implicated in several diseases, including auditory system disease (multiple); autosomal dominant Alport syndrome; blood platelet disease (multiple); end stage renal disease; and orofacial cleft. Orthologous to human MYH9 (myosin heavy chain 9).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C80049; cellular myosin heavy chain, type A; D0Jmb2; E030044M24Rik; Fl; flectin; Fltn; Myhn; Myhn-; Myhn-1; Myhn1; myosin heavy chain 9; myosin heavy chain IX; myosin heavy chain, non-muscle IIa; myosin IIA; myosin-9; NMHC II-A; NMHCIIA; NMMHC II-a; NMMHC-A; NMMHC-IIA; non-muscle myosin heavy chain A; non-muscle myosin heavy chain IIa; TU72.6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391577,644,785 - 77,726,375 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1577,644,787 - 77,726,375 (-)EnsemblGRCm39 Ensembl
GRCm381577,760,585 - 77,842,175 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1577,760,587 - 77,842,175 (-)EnsemblGRCm38mm10GRCm38
MGSCv371577,591,019 - 77,672,545 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361577,587,843 - 77,669,360 (-)NCBIMGSCv36mm8
Celera1579,227,040 - 79,308,545 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1536.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
7,12-dimethyltetraphene  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
blebbistatin  (EXP)
Brodifacoum  (ISO)
bucladesine  (ISO)
buspirone  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chloromethylisothiazolinone  (ISO)
chloropicrin  (ISO)
choline  (EXP)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
clobetasol  (EXP)
cobalt dichloride  (ISO)
cocaine  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (EXP)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP)
fenamidone  (EXP)
fenthion  (EXP)
folic acid  (EXP)
fructose  (ISO)
fumonisin B1  (EXP)
genistein  (ISO)
glafenine  (ISO)
hypochlorous acid  (EXP)
inulin  (EXP)
isobutanol  (ISO)
isoflavones  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
lipopolysaccharide  (ISO)
medroxyprogesterone acetate  (ISO)
methidathion  (EXP)
methylmercury chloride  (ISO)
miconazole  (EXP)
Monobutylphthalate  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
pirinixic acid  (EXP)
propanal  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP)
Soman  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thiophenes  (ISO)
Tributyltin oxide  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
troglitazone  (EXP)
tungsten  (EXP)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton reorganization  (ISO)
actin filament bundle assembly  (ISO)
actin filament bundle distribution  (ISO)
actin filament capping  (IDA)
actin filament polymerization  (IDA)
actin filament-based movement  (ISO)
actomyosin structure organization  (ISO)
angiogenesis  (ISO)
blood vessel endothelial cell migration  (ISO)
cell adhesion  (IMP)
cell morphogenesis involved in differentiation  (IMP)
cell-cell adhesion  (IMP,ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to platelet-derived growth factor stimulus  (ISO)
cortical granule exocytosis  (IMP)
cytokinetic process  (ISO)
establishment of meiotic spindle localization  (IDA)
establishment of T cell polarity  (IMP)
follicle-stimulating hormone signaling pathway  (ISO)
in utero embryonic development  (IMP)
lysosome localization  (ISO)
meiotic spindle organization  (IDA)
membrane protein ectodomain proteolysis  (ISO)
monocyte differentiation  (ISO)
myoblast fusion  (IMP)
negative regulation of actin filament severing  (IMP,ISO)
negative regulation of vascular associated smooth muscle cell migration  (ISO)
phagocytosis, engulfment  (IMP)
plasma membrane repair  (ISO)
platelet aggregation  (ISO)
platelet formation  (ISO)
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway  (ISO)
positive regulation of endocytosis  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of focal adhesion assembly  (ISO)
positive regulation of G protein-coupled receptor signaling pathway  (ISO)
positive regulation of inositol trisphosphate biosynthetic process  (ISO)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
positive regulation of phagocytosis  (ISO)
positive regulation of protein processing in phagocytic vesicle  (IMP)
protein transport  (ISO)
regulated exocytosis  (ISO)
regulation of cell shape  (IMP,ISO)
regulation of plasma membrane repair  (ISO)
uropod organization  (IMP)
vesicle targeting  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood coagulation  (IAGP)
abnormal brain vasculature morphology  (IAGP)
abnormal CD8-positive, alpha-beta T cell physiology  (IAGP)
abnormal cell adhesion  (IAGP)
abnormal cell migration  (IAGP)
abnormal cell morphology  (IAGP)
abnormal eye physiology  (IAGP)
abnormal germ layer development  (IAGP)
abnormal lens fiber morphology  (IAGP)
abnormal leukocyte adhesion  (IAGP)
abnormal leukocyte migration  (IAGP)
abnormal lymph node cell ratio  (IAGP)
abnormal megakaryocyte differentiation  (IAGP)
abnormal megakaryocyte morphology  (IAGP)
abnormal neutrophil morphology  (IAGP)
abnormal placenta fetal blood space morphology  (IAGP)
abnormal placenta intervillous maternal lacunae morphology  (IAGP)
abnormal placenta labyrinth morphology  (IAGP)
abnormal placenta morphology  (IAGP)
abnormal placenta size  (IAGP)
abnormal placental labyrinth vasculature morphology  (IAGP)
abnormal platelet morphology  (IAGP)
abnormal platelet physiology  (IAGP)
abnormal platelet shape  (IAGP)
abnormal podocyte morphology  (IAGP)
abnormal spongiotrophoblast layer morphology  (IAGP)
abnormal T cell physiology  (IAGP)
abnormal thrombopoiesis  (IAGP)
abnormal vascular branching morphogenesis  (IAGP)
abnormal visceral endoderm morphology  (IAGP)
abnormal vitelline vasculature morphology  (IAGP)
albuminuria  (IAGP)
cataract  (IAGP)
corneal vascularization  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased embryo size  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
failure to gastrulate  (IAGP)
fused podocyte foot processes  (IAGP)
glomerulosclerosis  (IAGP)
hematuria  (IAGP)
impaired hearing  (IAGP)
increased bleeding time  (IAGP)
increased incidence of corneal inflammation  (IAGP)
increased megakaryocyte cell number  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
increased renal glomerulus basement membrane thickness  (IAGP)
increased sensitivity to induced morbidity/mortality  (IAGP)
increased susceptibility to age-related hearing loss  (IAGP)
increased susceptibility to injury  (IAGP)
no abnormal phenotype detected  (IAGP)
pale yolk sac  (IAGP)
podocyte foot process effacement  (IAGP)
podocyte microvillus transformation  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
renal cast  (IAGP)
thin placenta labyrinth  (IAGP)
thrombocytopenia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Expression of the nonmuscle myosin heavy chain IIA in the human kidney and screening for MYH9 mutations in Epstein and Fechtner syndromes. Arrondel C, etal., J Am Soc Nephrol. 2002 Jan;13(1):65-74.
2. MYH9 and APOL1 are both associated with sickle cell disease nephropathy. Ashley-Koch AE, etal., Br J Haematol. 2011 Nov;155(3):386-94. doi: 10.1111/j.1365-2141.2011.08832.x. Epub 2011 Sep 13.
3. African ancestry allelic variation at the MYH9 gene contributes to increased susceptibility to non-diabetic end-stage kidney disease in Hispanic Americans. Behar DM, etal., Hum Mol Genet. 2010 May 1;19(9):1816-27. Epub 2010 Feb 9.
4. Further evidence for the involvement of MYH9 in the etiology of non-syndromic cleft lip with or without cleft palate. Birnbaum S, etal., Eur J Oral Sci. 2009 Apr;117(2):200-3. doi: 10.1111/j.1600-0722.2008.00604.x.
5. Genomic screening identifies novel linkages and provides further evidence for a role of MYH9 in nonsyndromic cleft lip and palate. Chiquet BT, etal., Eur J Hum Genet. 2009 Feb;17(2):195-204. doi: 10.1038/ejhg.2008.149. Epub 2008 Aug 20.
6. Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans. Cooke JN, etal., Nephrol Dial Transplant. 2012 Apr;27(4):1505-11. Epub 2011 Oct 3.
7. Polymorphisms in the nonmuscle myosin heavy chain 9 gene (MYH9) are associated with albuminuria in hypertensive African Americans: the HyperGEN study. Freedman BI, etal., Am J Nephrol. 2009;29(6):626-32. Epub 2009 Jan 20.
8. Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans. Freedman BI, etal., Kidney Int. 2009 Apr;75(7):736-45. Epub 2009 Jan 28.
9. Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD. Freedman BI, etal., Nephrol Dial Transplant. 2009 Nov;24(11):3366-71. Epub 2009 Jun 30.
10. Alterations in expression of myosin and myosin light chain kinases in response to vascular injury. Gallagher PJ, etal., Am J Physiol Cell Physiol. 2000 Oct;279(4):C1078-87.
11. Genetics, clinical and pathological features of glomerulonephritis associated with mutations of nonmuscle myosin IIA (Fechtner syndrome). Ghiggeri GM, etal., Am J Kidney Dis. 2003 Jan;41(1):95-104.
12. Glomerular MYH9 expression is reduced by HIV-1. Hays T, etal., AIDS. 2012 Apr 24;26(7):797-803.
13. Association among polymorphisms at MYH9, environmental factors, and nonsyndromic orofacial clefts in western China. Jia ZL, etal., DNA Cell Biol. 2010 Jan;29(1):25-32. doi: 10.1089/dna.2009.0935.
14. Podocyte-specific deletion of Myh9 encoding nonmuscle myosin heavy chain 2A predisposes mice to glomerulopathy. Johnstone DB, etal., Mol Cell Biol. 2011 May;31(10):2162-70. Epub 2011 Mar 14.
15. MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Kao WH, etal., Nat Genet. 2008 Oct;40(10):1185-92. Epub 2008 Sep 14.
16. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
17. Human nonsyndromic hereditary deafness DFNA17 is due to a mutation in nonmuscle myosin MYH9. Lalwani AK, etal., Am J Hum Genet. 2000 Nov;67(5):1121-8. Epub 2000 Oct 9.
18. Cleft lip with or without cleft palate: implication of the heavy chain of non-muscle myosin IIA. Martinelli M, etal., J Med Genet. 2007 Jun;44(6):387-92. Epub 2007 Mar 2.
19. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
20. MGDs mouse GO annotations MGD data from the GO Consortium
21. MGD IEA MGD IEA
22. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
23. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
24. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
25. Mouse MP Annotation Import Pipeline RGD automated import pipeline
26. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
27. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
28. Patients with Epstein-Fechtner syndromes owing to MYH9 R702 mutations develop progressive proteinuric renal disease. Sekine T, etal., Kidney Int. 2010 Jul;78(2):207-14. Epub 2010 Mar 3.
29. Epstein syndrome: another renal disorder with mutations in the nonmuscle myosin heavy chain 9 gene. Seri M, etal., Hum Genet. 2002 Feb;110(2):182-6. Epub 2001 Dec 14.
30. Mutations in MYH9 result in the May-Hegglin anomaly, and Fechtner and Sebastian syndromes. The May-Heggllin/Fechtner Syndrome Consortium. Seri M, etal., Nat Genet. 2000 Sep;26(1):103-5.
31. Establishment of mouse model of MYH9 disorders: heterozygous R702C mutation provokes macrothrombocytopenia with leukocyte inclusion bodies, renal glomerulosclerosis and hearing disability. Suzuki N, etal., PLoS One. 2013 Aug 20;8(8):e71187. doi: 10.1371/journal.pone.0071187. eCollection 2013.
32. Genetic variation in APOL1 and MYH9 genes is associated with chronic kidney disease among Nigerians. Tayo BO, etal., Int Urol Nephrol. 2013 Apr;45(2):485-94. doi: 10.1007/s11255-012-0263-4. Epub 2012 Sep 7.
33. Nonmuscle Myosin Heavy Chain IIA Mutation Predicts Severity and Progression of Sensorineural Hearing Loss in Patients With MYH9-Related Disease. Verver EJ, etal., Ear Hear. 2016 Jan-Feb;37(1):112-20. doi: 10.1097/AUD.0000000000000198.
34. Proteomic profiling of the effect of metabolic acidosis on the apical membrane of the proximal convoluted tubule. Walmsley SJ, etal., Am J Physiol Renal Physiol. 2012 Jun 1;302(11):F1465-77. doi: 10.1152/ajprenal.00390.2011. Epub 2012 Feb 22.
35. Analysis of clinical manifestations, mutant gene and encoded protein in two Chinese MYH9-related disease families. Yi Y, etal., Clin Chim Acta. 2006 Nov;373(1-2):49-54. Epub 2006 May 16.
Additional References at PubMed
PMID:1354638   PMID:1602141   PMID:2813355   PMID:8089273   PMID:8402956   PMID:8482409   PMID:8889548   PMID:9356462   PMID:9725909   PMID:9798653   PMID:9842715   PMID:9878787  
PMID:10349636   PMID:10512203   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11283949   PMID:11943476   PMID:12477932   PMID:12520002   PMID:12893741   PMID:12904583   PMID:14594953  
PMID:14610273   PMID:15034141   PMID:15064761   PMID:15079858   PMID:15177565   PMID:15292239   PMID:15449545   PMID:15555549   PMID:15782199   PMID:15840001   PMID:16012337   PMID:16141072  
PMID:16141073   PMID:16186248   PMID:16407977   PMID:16452087   PMID:16630581   PMID:16862555   PMID:16895968   PMID:16959763   PMID:17208939   PMID:17310241   PMID:17392504   PMID:17429076  
PMID:17459090   PMID:17615572   PMID:17623278   PMID:17664350   PMID:17914179   PMID:17967808   PMID:17997715   PMID:18241845   PMID:18307411   PMID:18394644   PMID:18697221   PMID:18714354  
PMID:18799693   PMID:18984861   PMID:19015242   PMID:19027000   PMID:19109430   PMID:19201857   PMID:19269977   PMID:19401332   PMID:19439495   PMID:19552622   PMID:19968963   PMID:20007545  
PMID:20067993   PMID:20099318   PMID:20223754   PMID:20572855   PMID:20679233   PMID:20685736   PMID:20695978   PMID:20723023   PMID:20835229   PMID:20932596   PMID:21126233   PMID:21216307  
PMID:21224395   PMID:21267068   PMID:21327095   PMID:21396893   PMID:21565611   PMID:21659539   PMID:21677750   PMID:21725061   PMID:21873635   PMID:21908426   PMID:22114352   PMID:22191382  
PMID:22234693   PMID:22253476   PMID:22328520   PMID:22347397   PMID:22393000   PMID:22560610   PMID:22751140   PMID:22820068   PMID:22972683   PMID:23180766   PMID:23195221   PMID:23305739  
PMID:23325791   PMID:23874454   PMID:23900075   PMID:23911870   PMID:24213535   PMID:24243973   PMID:24374234   PMID:24436421   PMID:24457600   PMID:24614889   PMID:24711500   PMID:24777479  
PMID:24778310   PMID:24780566   PMID:24825879   PMID:24855944   PMID:24952961   PMID:25006807   PMID:25133611   PMID:25158168   PMID:25168025   PMID:25180062   PMID:25185263   PMID:25307162  
PMID:25637353   PMID:25848986   PMID:25881103   PMID:25926623   PMID:25931194   PMID:25968904   PMID:26126491   PMID:26167872   PMID:26369831   PMID:26370502   PMID:26430214   PMID:26496610  
PMID:26975831   PMID:27063635   PMID:27478065   PMID:27487217   PMID:27503502   PMID:27882344   PMID:28114272   PMID:28153611   PMID:28361956   PMID:28378742   PMID:28478097   PMID:28526784  
PMID:28552735   PMID:28600434   PMID:28634551   PMID:28671696   PMID:28687623   PMID:28821574   PMID:28993503   PMID:29084269   PMID:29158485   PMID:29195076   PMID:29208598   PMID:29247647  
PMID:29254152   PMID:29459677   PMID:29487177   PMID:29518331   PMID:29530978   PMID:29676259   PMID:29689194   PMID:29791846   PMID:29932067   PMID:29956586   PMID:29981310   PMID:29996102  
PMID:30044719   PMID:30068598   PMID:30280293   PMID:30333137   PMID:30409884   PMID:30550785   PMID:30562941   PMID:30666520   PMID:30886905   PMID:30995168   PMID:31064828   PMID:31118423  
PMID:31118506   PMID:31162944   PMID:31189591   PMID:31189957   PMID:31235578   PMID:31253773   PMID:31577226   PMID:32315395   PMID:32320663   PMID:32325033   PMID:32513915   PMID:32554809  
PMID:32583739   PMID:32664526   PMID:32888949   PMID:32902730   PMID:33001861   PMID:33188738   PMID:33424621   PMID:33754063   PMID:33842485   PMID:33871354   PMID:33891868   PMID:33903241  
PMID:33986190   PMID:34029538   PMID:34078910   PMID:34131310   PMID:34193158   PMID:34302166   PMID:34474245   PMID:34910930   PMID:35428815   PMID:35493485   PMID:35584211   PMID:35601919  
PMID:35740994   PMID:35759156   PMID:35764499   PMID:36172862   PMID:36220082   PMID:36293380   PMID:36417873   PMID:37070941  


Genomics

Comparative Map Data
Myh9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391577,644,785 - 77,726,375 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1577,644,787 - 77,726,375 (-)EnsemblGRCm39 Ensembl
GRCm381577,760,585 - 77,842,175 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1577,760,587 - 77,842,175 (-)EnsemblGRCm38mm10GRCm38
MGSCv371577,591,019 - 77,672,545 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361577,587,843 - 77,669,360 (-)NCBIMGSCv36mm8
Celera1579,227,040 - 79,308,545 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1536.81NCBI
MYH9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382236,281,280 - 36,387,967 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2236,281,280 - 36,388,010 (-)EnsemblGRCh38hg38GRCh38
GRCh372236,677,326 - 36,784,012 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362235,007,272 - 35,113,927 (-)NCBINCBI36Build 36hg18NCBI36
Build 342235,001,826 - 35,108,481NCBI
Celera2220,479,895 - 20,586,681 (-)NCBICelera
Cytogenetic Map22q12.3NCBI
HuRef2219,645,404 - 19,752,216 (-)NCBIHuRef
CHM1_12236,636,447 - 36,743,196 (-)NCBICHM1_1
T2T-CHM13v2.02236,741,430 - 36,848,142 (-)NCBIT2T-CHM13v2.0
Myh9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27109,343,718 - 109,424,457 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7109,343,706 - 109,424,457 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7111,099,271 - 111,152,015 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.07113,322,832 - 113,375,576 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.07113,284,741 - 113,337,445 (-)NCBIRnor_WKY
Rnor_6.07118,740,005 - 118,792,507 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7118,741,110 - 118,792,625 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl7118,992,356 - 119,071,712 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07118,737,555 - 118,797,086 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47115,681,459 - 115,732,774 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17115,715,686 - 115,767,004 (-)NCBI
Celera7105,684,430 - 105,736,878 (-)NCBICelera
RH 3.4 Map7811.2RGD
Cytogenetic Map7q34NCBI
Myh9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541322,881,045 - 22,972,450 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541322,881,759 - 22,972,182 (-)NCBIChiLan1.0ChiLan1.0
MYH9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan12248,831,242 - 48,936,531 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02217,200,623 - 17,305,826 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12235,039,461 - 35,121,618 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2235,039,101 - 35,121,618 (-)Ensemblpanpan1.1panPan2
MYH9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11028,063,626 - 28,122,953 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1028,063,624 - 28,122,953 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1027,985,072 - 28,076,495 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01028,817,559 - 28,909,010 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1028,817,514 - 28,909,028 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11028,544,285 - 28,635,641 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01028,853,021 - 28,944,583 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01029,031,010 - 29,122,482 (+)NCBIUU_Cfam_GSD_1.0
Myh9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494511,373,869 - 11,455,815 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364924,384,215 - 4,466,262 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049364924,384,215 - 4,466,229 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYH9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl511,360,660 - 11,456,472 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1511,365,603 - 11,456,475 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.259,076,302 - 9,165,918 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYH9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11918,985,709 - 19,093,304 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1918,986,598 - 19,052,671 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045106,805,704 - 106,913,198 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myh9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475211,327,877 - 11,413,669 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475211,327,881 - 11,414,037 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Myh9
1977 total Variants
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mirlet7f-2mmu-let-7f-5pOncomiRDBexternal_infoNANA21533124

Predicted Target Of
Summary Value
Count of predictions:2102
Count of miRNA genes:796
Interacting mature miRNAs:1011
Transcripts:ENSMUST00000016771, ENSMUST00000123101, ENSMUST00000124844, ENSMUST00000126796, ENSMUST00000129453, ENSMUST00000134878, ENSMUST00000139729
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1357703Vtbt17_mvertebral trabecular bone trait 17 (mouse)Not determined154455331378553437Mouse
1301568Tria2_mT-cell receptor induced activation 2 (mouse)Not determined154485914178859281Mouse
1357756Alaa4_malopecia areata 4 (mouse)Not determined154638964680389845Mouse
10755515Amzn3_manatomical modifier of Zfp423 3 (mouse)154638964680389845Mouse
1301006Hfib1_mhepatic fibrogenesis 1 (mouse)Not determined154730633481306479Mouse
1301860Gct3_mgranulosa cell tumorigenesis 3 (mouse)Not determined154740959681409691Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1558786Msq1_mMAV-1 susceptibility QTL 1 (mouse)Not determined156338964681086436Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1302002Cocia2_mcocaine induced activation 2 (mouse)Not determined157237245979899178Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157410054082674156Mouse
13442492Mecth2_mmechanosensation threshold 2 (mouse)157466284979387201Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse

Markers in Region
UniSTS:237340  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381577,835,647 - 77,835,781UniSTSGRCm38
MGSCv371577,666,077 - 77,666,211UniSTSGRCm37
Celera1579,302,072 - 79,302,206UniSTS
Cytogenetic Map15E1UniSTS
cM Map1543.3UniSTS
C80049  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381577,760,833 - 77,760,918UniSTSGRCm38
MGSCv371577,591,263 - 77,591,348UniSTSGRCm37
Celera1579,227,284 - 79,227,369UniSTS
Cytogenetic Map15E1UniSTS
cM Map1543.3UniSTS
Whitehead/MRC_RH15700.66UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_022410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ312390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL583886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC044834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC116417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC116418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC128059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC128497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC128498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ130312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ240806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M88754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U89401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000016771   ⟹   ENSMUSP00000016771
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1577,644,787 - 77,726,375 (-)Ensembl
GRCm38.p6 Ensembl1577,760,587 - 77,842,175 (-)Ensembl
RefSeq Acc Id: ENSMUST00000123101   ⟹   ENSMUSP00000116198
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1577,674,941 - 77,726,247 (-)Ensembl
GRCm38.p6 Ensembl1577,790,741 - 77,842,047 (-)Ensembl
RefSeq Acc Id: ENSMUST00000124844
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1577,678,852 - 77,697,431 (-)Ensembl
GRCm38.p6 Ensembl1577,794,652 - 77,813,231 (-)Ensembl
RefSeq Acc Id: ENSMUST00000126796
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1577,672,391 - 77,726,256 (-)Ensembl
GRCm38.p6 Ensembl1577,788,191 - 77,842,056 (-)Ensembl
RefSeq Acc Id: ENSMUST00000129453
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1577,674,425 - 77,726,305 (-)Ensembl
GRCm38.p6 Ensembl1577,790,225 - 77,842,105 (-)Ensembl
RefSeq Acc Id: ENSMUST00000134878
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1577,689,746 - 77,726,305 (-)Ensembl
GRCm38.p6 Ensembl1577,805,546 - 77,842,105 (-)Ensembl
RefSeq Acc Id: ENSMUST00000139729
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1577,649,528 - 77,651,390 (-)Ensembl
GRCm38.p6 Ensembl1577,765,328 - 77,767,190 (-)Ensembl
RefSeq Acc Id: ENSMUST00000229259   ⟹   ENSMUSP00000155471
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1577,648,161 - 77,653,979 (-)Ensembl
GRCm38.p6 Ensembl1577,763,961 - 77,769,779 (-)Ensembl
RefSeq Acc Id: ENSMUST00000231192   ⟹   ENSMUSP00000155562
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1577,658,235 - 77,665,333 (-)Ensembl
GRCm38.p6 Ensembl1577,774,035 - 77,781,133 (-)Ensembl
RefSeq Acc Id: NM_022410   ⟹   NP_071855
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391577,644,785 - 77,726,375 (-)NCBI
GRCm381577,760,585 - 77,842,175 (-)NCBI
MGSCv371577,591,019 - 77,672,545 (-)RGD
Celera1579,227,036 - 79,308,605 (-)NCBI
cM Map15 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_071855 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC36508 (Get FASTA)   NCBI Sequence Viewer  
  AAH06075 (Get FASTA)   NCBI Sequence Viewer  
  AAH43703 (Get FASTA)   NCBI Sequence Viewer  
  AAH44834 (Get FASTA)   NCBI Sequence Viewer  
  AAH54360 (Get FASTA)   NCBI Sequence Viewer  
  AAI16418 (Get FASTA)   NCBI Sequence Viewer  
  AAI16419 (Get FASTA)   NCBI Sequence Viewer  
  AAI28060 (Get FASTA)   NCBI Sequence Viewer  
  AAI28498 (Get FASTA)   NCBI Sequence Viewer  
  AAI28499 (Get FASTA)   NCBI Sequence Viewer  
  BAC30712 (Get FASTA)   NCBI Sequence Viewer  
  BAC38752 (Get FASTA)   NCBI Sequence Viewer  
  BAD21421 (Get FASTA)   NCBI Sequence Viewer  
  BAE27761 (Get FASTA)   NCBI Sequence Viewer  
  BAE27763 (Get FASTA)   NCBI Sequence Viewer  
  BAE27765 (Get FASTA)   NCBI Sequence Viewer  
  BAE27766 (Get FASTA)   NCBI Sequence Viewer  
  BAE27767 (Get FASTA)   NCBI Sequence Viewer  
  BAE27768 (Get FASTA)   NCBI Sequence Viewer  
  BAE27772 (Get FASTA)   NCBI Sequence Viewer  
  BAE27773 (Get FASTA)   NCBI Sequence Viewer  
  BAE27776 (Get FASTA)   NCBI Sequence Viewer  
  BAE27777 (Get FASTA)   NCBI Sequence Viewer  
  BAE27778 (Get FASTA)   NCBI Sequence Viewer  
  BAE27783 (Get FASTA)   NCBI Sequence Viewer  
  BAE27785 (Get FASTA)   NCBI Sequence Viewer  
  BAE27829 (Get FASTA)   NCBI Sequence Viewer  
  BAE27894 (Get FASTA)   NCBI Sequence Viewer  
  BAE27906 (Get FASTA)   NCBI Sequence Viewer  
  BAE28480 (Get FASTA)   NCBI Sequence Viewer  
  CAC85955 (Get FASTA)   NCBI Sequence Viewer  
  EDL29650 (Get FASTA)   NCBI Sequence Viewer  
  Q8VDD5 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_071855   ⟸   NM_022410
- UniProtKB: Q811I2 (UniProtKB/Swiss-Prot),   Q8VDD5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000155562   ⟸   ENSMUST00000231192
RefSeq Acc Id: ENSMUSP00000016771   ⟸   ENSMUST00000016771
RefSeq Acc Id: ENSMUSP00000116198   ⟸   ENSMUST00000123101
RefSeq Acc Id: ENSMUSP00000155471   ⟸   ENSMUST00000229259
Protein Domains
IQ   Myosin motor   Myosin N-terminal SH3-like   Myosin tail

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VDD5-F1-model_v2 AlphaFold Q8VDD5 1-1960 view protein structure

Promoters
RGD ID:6826239
Promoter ID:MM_KWN:18952
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000039569
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361577,597,366 - 77,598,047 (-)MPROMDB
RGD ID:6847228
Promoter ID:MM_ACW:18564
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:MYH9.ISEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361577,599,461 - 77,600,412 (-)MPROMDB
RGD ID:6847224
Promoter ID:MM_ACW:18565
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:MYH9.NSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361577,607,366 - 77,608,492 (-)MPROMDB
RGD ID:6847223
Promoter ID:MM_ACW:18566
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:MYH9.ESEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361577,611,689 - 77,612,189 (-)MPROMDB
RGD ID:6826240
Promoter ID:MM_KWN:18953
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000109752
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361577,612,761 - 77,613,982 (-)MPROMDB
RGD ID:6847225
Promoter ID:MM_ACW:18567
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Kidney,   MEF_B4,   Spleen
Transcripts:MYH9.MSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361577,622,421 - 77,622,921 (-)MPROMDB
RGD ID:6826237
Promoter ID:MM_KWN:18954
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000039567
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361577,643,191 - 77,644,392 (-)MPROMDB
RGD ID:6826238
Promoter ID:MM_KWN:18957
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000065458,   OTTMUST00000039563,   OTTMUST00000039564,   OTTMUST00000039568,   UC007WOD.1,   UC007WOE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361577,672,361 - 77,673,262 (-)MPROMDB
RGD ID:8684222
Promoter ID:EPDNEW_M20141
Type:initiation region
Name:Myh9_1
Description:Mus musculus myosin, heavy polypeptide 9, non-muscle , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381577,842,115 - 77,842,175EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107717 AgrOrtholog
Ensembl Genes ENSMUSG00000022443 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000016771 ENTREZGENE
  ENSMUSP00000016771.7 UniProtKB/Swiss-Prot
  ENSMUSP00000116198.2 UniProtKB/TrEMBL
  ENSMUSP00000155471.2 UniProtKB/TrEMBL
  ENSMUSP00000155562.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000016771 ENTREZGENE
  ENSMUST00000016771.13 UniProtKB/Swiss-Prot
  ENSMUST00000123101.8 UniProtKB/TrEMBL
  ENSMUST00000229259.2 UniProtKB/TrEMBL
  ENSMUST00000231192.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/Swiss-Prot
  1.20.5.340 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/Swiss-Prot
  2.30.30.360 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.1590 UniProtKB/Swiss-Prot
  3.40.850.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.2420 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/Swiss-Prot
  Myosin, subunit A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro IQ_motif_EF-hand-BS UniProtKB/Swiss-Prot
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_S1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_tail UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17886 UniProtKB/Swiss-Prot
MGD MGI:107717 ENTREZGENE
NCBI Gene 17886 ENTREZGENE
PANTHER CINGULIN UniProtKB/TrEMBL
  CINGULIN-LIKE PROTEIN 1-RELATED UniProtKB/TrEMBL
  MYOSIN UniProtKB/TrEMBL
  MYOSIN HEAVY CHAIN, NON-MUSCLE UniProtKB/Swiss-Prot
  MYOSIN HEAVY CHAIN, NON-MUSCLE UniProtKB/Swiss-Prot
  MYOSIN HEAVY CHAIN, NON-MUSCLE UniProtKB/TrEMBL
  MYOSIN HEAVY CHAIN, NON-MUSCLE UniProtKB/TrEMBL
  MYOSIN-2 UniProtKB/TrEMBL
  MYOSIN-9 UniProtKB/TrEMBL
Pfam Myosin_head UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_tail_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Myh9 PhenoGen
PRINTS MYOSINHEAVY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50096 UniProtKB/Swiss-Prot
  SH3_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART MYSc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00015 UniProtKB/Swiss-Prot
Superfamily-SCOP Myosin rod fragments UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tropomyosin UniProtKB/TrEMBL
UniProt A0A2R8VKI5_MOUSE UniProtKB/TrEMBL
  A0A2R8W6V7_MOUSE UniProtKB/TrEMBL
  A2VCK0_MOUSE UniProtKB/TrEMBL
  F2Z494_MOUSE UniProtKB/TrEMBL
  MYH9_MOUSE UniProtKB/Swiss-Prot
  O89055_MOUSE UniProtKB/TrEMBL
  Q14B05_MOUSE UniProtKB/TrEMBL
  Q3UFT0_MOUSE UniProtKB/TrEMBL
  Q7TQJ6_MOUSE UniProtKB/TrEMBL
  Q811I2 ENTREZGENE
  Q811J9_MOUSE UniProtKB/TrEMBL
  Q8BIE2_MOUSE UniProtKB/TrEMBL
  Q8BIM8_MOUSE UniProtKB/TrEMBL
  Q8VDD5 ENTREZGENE
  Q99JJ3_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3UHT9 UniProtKB/Swiss-Prot
  Q3UHU4 UniProtKB/Swiss-Prot
  Q6KAN6 UniProtKB/Swiss-Prot
  Q811I2 UniProtKB/Swiss-Prot