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Gene: IGFBP5 (insulin like growth factor binding protein 5) Homo sapiens
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Symbol: IGFBP5
Name: insulin like growth factor binding protein 5
RGD ID: 732384
Description: Exhibits insulin-like growth factor I binding activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of smooth muscle cell proliferation. Localizes to insulin-like growth factor ternary complex. Biomarker of pulmonary fibrosis; PARTICIPATES IN insulin-like growth factor signaling pathway; INTERACTS WITH (+)-catechin; 14-Deoxy-11,12-didehydroandrographolide; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IBP-5; IBP5; IGF-binding protein 5; IGFBP-5; insulin-like growth factor binding protein 5; insulin-like growth factor-binding protein 5
Orthologs:
Mus musculus (house mouse) : Igfbp5 (insulin-like growth factor binding protein 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Igfbp5 (insulin-like growth factor binding protein 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igfbp5 (insulin like growth factor binding protein 5)
Pan paniscus (bonobo/pygmy chimpanzee) : IGFBP5 (insulin like growth factor binding protein 5)
Canis lupus familiaris (dog) : IGFBP5 (insulin like growth factor binding protein 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igfbp5 (insulin like growth factor binding protein 5)
Sus scrofa (pig) : IGFBP5 (insulin like growth factor binding protein 5)
Chlorocebus sabaeus (African green monkey) : IGFBP5 (insulin like growth factor binding protein 5)
Heterocephalus glaber (naked mole-rat) : Igfbp5 (insulin like growth factor binding protein 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2216,672,105 - 216,695,549 (-)EnsemblGRCh38hg38GRCh38
GRCh382216,672,105 - 216,695,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372217,536,828 - 217,560,272 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,245,073 - 217,268,516 (-)NCBINCBI36hg18NCBI36
Build 342217,362,334 - 217,385,777NCBI
Celera2211,304,716 - 211,328,161 (-)NCBI
Cytogenetic Map2q35NCBI
HuRef2209,391,205 - 209,414,636 (-)NCBIHuRef
CHM1_12217,543,006 - 217,566,425 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IGFBP5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732384
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.