Gene: HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2) Homo sapiens
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Symbol: HCN2
Name: hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
Description: The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of epilepsy. [provided by RefSeq, Jan 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BCNG-2; BCNG2; brain cyclic nucleotide gated channel 2; brain cyclic nucleotide-gated channel 2; HAC-1; hyperpolarization activated cyclic nucleotide gated potassium channel 2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Orthologs:
Mus musculus (house mouse) : Hcn2 (hyperpolarization-activated, cyclic nucleotide-gated K+ 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hcn2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hcn2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hcn2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819589,893 - 617,159 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3719589,893 - 617,159 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619540,893 - 568,159 (+)NCBINCBI36hg18NCBI36
Build 3419540,892 - 568,157NCBI
Celera19200,463 - 228,092 (-)NCBI
Cytogenetic Map19p13.3NCBI
HuRef19373,968 - 384,301 (+)NCBIHuRef
CHM1_119589,749 - 616,575 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Nomenclature History
  
More on HCN2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732305
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2018-08-14
Status: ACTIVE



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