TENM2 (teneurin transmembrane protein 2) - Rat Genome Database

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Gene: TENM2 (teneurin transmembrane protein 2) Homo sapiens
Analyze
Symbol: TENM2
Name: teneurin transmembrane protein 2
RGD ID: 732274
HGNC Page HGNC
Description: Enables cell adhesion molecule binding activity and signaling receptor binding activity. Involved in several processes, including calcium-mediated signaling using intracellular calcium source; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and retrograde trans-synaptic signaling by trans-synaptic protein complex. Located in cell-cell junction and plasma membrane; INTERACTS WITH (-)-demecolcine; 17beta-estradiol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp686A1568; neurestin alpha; odd Oz/ten-m homolog 2; odd oz/ten-m homolog 2 (drosophila); odz, odd Oz/ten-m homolog 2; ODZ2; ten-2; TEN-M2; TEN2; tenascin-M2; teneurin 2; teneurin-2; TNM2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5167,284,799 - 168,264,157 (+)EnsemblGRCh38hg38GRCh38
GRCh385166,979,066 - 168,264,159 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375166,500,247 - 167,691,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365167,114,519 - 167,623,740 (+)NCBINCBI36hg18NCBI36
Build 345167,477,951 - 167,623,739NCBI
Celera5162,750,499 - 163,726,534 (+)NCBI
Cytogenetic Map5q34NCBI
HuRef5161,812,425 - 162,791,103 (+)NCBIHuRef
CHM1_15166,144,311 - 167,124,193 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

Additional References at PubMed
PMID:10225957   PMID:10574461   PMID:10625539   PMID:10737800   PMID:12783990   PMID:14702039   PMID:15372022   PMID:17081983   PMID:18927281   PMID:20379614   PMID:21724987   PMID:21873635  
PMID:22229870   PMID:22610502   PMID:22699663   PMID:23636237   PMID:25133637   PMID:25231870   PMID:28088466   PMID:29568061   PMID:30457553   PMID:30945288  


Genomics

Comparative Map Data
TENM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5167,284,799 - 168,264,157 (+)EnsemblGRCh38hg38GRCh38
GRCh385166,979,066 - 168,264,159 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375166,500,247 - 167,691,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365167,114,519 - 167,623,740 (+)NCBINCBI36hg18NCBI36
Build 345167,477,951 - 167,623,739NCBI
Celera5162,750,499 - 163,726,534 (+)NCBI
Cytogenetic Map5q34NCBI
HuRef5161,812,425 - 162,791,103 (+)NCBIHuRef
CHM1_15166,144,311 - 167,124,193 (+)NCBICHM1_1
Tenm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,897,483 - 37,881,486 (-)NCBIGRCm39mm39
GRCm39 Ensembl1135,897,483 - 37,126,791 (-)Ensembl
GRCm381136,006,656 - 37,237,053 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1136,006,656 - 37,235,964 (-)EnsemblGRCm38mm10GRCm38
MGSCv371135,820,171 - 36,757,745 (-)NCBIGRCm37mm9NCBIm37
MGSCv361135,851,071 - 36,787,666 (-)NCBImm8
Celera1140,009,205 - 40,811,666 (-)NCBICelera
Cytogenetic Map11A4- A5NCBI
cM Map1121.96NCBI
Tenm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21020,480,662 - 21,706,415 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1020,481,854 - 21,705,597 (-)Ensembl
Rnor_6.01020,846,091 - 21,791,771 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1020,844,899 - 21,265,026 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01020,716,458 - 21,659,087 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41020,939,207 - 21,888,443 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11020,940,255 - 22,096,609 (-)NCBI
Celera1020,101,901 - 21,233,134 (-)NCBICelera
Cytogenetic Map10q12NCBI
Tenm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540820,437,067 - 21,338,897 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540820,150,223 - 21,340,276 (+)NCBIChiLan1.0ChiLan1.0
TENM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15169,420,475 - 170,392,593 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5169,420,480 - 170,392,581 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05162,346,710 - 163,627,371 (+)NCBIMhudiblu_PPA_v0panPan3
TENM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1443,450,278 - 44,962,993 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl443,451,059 - 44,377,371 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha443,408,748 - 44,060,223 (-)NCBI
ROS_Cfam_1.0443,873,657 - 44,519,117 (-)NCBI
UMICH_Zoey_3.1443,643,674 - 44,287,381 (-)NCBI
UNSW_CanFamBas_1.0443,838,128 - 44,482,532 (-)NCBI
UU_Cfam_GSD_1.0444,344,597 - 44,989,412 (-)NCBI
Tenm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721397,485,971 - 98,368,217 (-)NCBI
SpeTri2.0NW_0049366221,101,587 - 1,983,816 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TENM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1655,625,298 - 56,915,287 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11655,624,273 - 59,084,150 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21660,189,355 - 61,223,392 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TENM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12369,206,076 - 70,487,159 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660348,199,738 - 9,519,849 (-)NCBIVero_WHO_p1.0
Tenm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473321,732,997 - 22,921,889 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D5S1471  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375166,876,472 - 166,876,638UniSTSGRCh37
Build 365166,809,050 - 166,809,216RGDNCBI36
Celera5162,912,392 - 162,912,550RGD
Cytogenetic Map5q34UniSTS
HuRef5161,976,865 - 161,977,034UniSTS
Marshfield Genetic Map5172.13RGD
Marshfield Genetic Map5172.13UniSTS
deCODE Assembly Map5173.71UniSTS
Stanford-G3 RH Map55917.0UniSTS
Whitehead-YAC Contig Map5 UniSTS
D5S619  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375166,881,403 - 166,881,655UniSTSGRCh37
GRCh375166,881,620 - 166,881,728UniSTSGRCh37
GRCh373126,819,020 - 126,819,451UniSTSGRCh37
Build 363128,301,710 - 128,302,141RGDNCBI36
Celera3125,243,552 - 125,243,983RGD
Celera5162,917,565 - 162,917,673UniSTS
Celera5162,917,350 - 162,917,600UniSTS
Cytogenetic Map5q34UniSTS
HuRef5161,981,813 - 161,982,061UniSTS
HuRef5161,982,026 - 161,982,134UniSTS
HuRef1947,993,330 - 47,993,822UniSTS
HuRef695,640,168 - 95,640,691UniSTS
Marshfield Genetic Map5172.67RGD
Genethon Genetic Map5173.2UniSTS
TNG Radiation Hybrid Map577782.0UniSTS
deCODE Assembly Map5173.71UniSTS
Stanford-G3 RH Map55912.0UniSTS
GeneMap99-GB4 RH Map5626.67UniSTS
Whitehead-YAC Contig Map5 UniSTS
GeneMap99-G3 RH Map56000.0UniSTS
D5S1458  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,575,791 - 167,575,974UniSTSGRCh37
Build 365167,508,369 - 167,508,552RGDNCBI36
Celera5163,611,132 - 163,611,315RGD
Cytogenetic Map5q34UniSTS
HuRef5162,675,680 - 162,675,863UniSTS
Marshfield Genetic Map5172.67RGD
Marshfield Genetic Map5172.67UniSTS
deCODE Assembly Map5175.18UniSTS
Whitehead-YAC Contig Map5 UniSTS
D5S496  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375166,995,629 - 166,995,816UniSTSGRCh37
GRCh375166,995,632 - 166,995,767UniSTSGRCh37
Build 365166,928,207 - 166,928,394RGDNCBI36
Celera5163,031,596 - 163,031,733UniSTS
Celera5163,031,593 - 163,031,782RGD
Cytogenetic Map5q34UniSTS
HuRef5162,096,147 - 162,096,284UniSTS
HuRef5162,096,144 - 162,096,333UniSTS
Marshfield Genetic Map5172.13UniSTS
Marshfield Genetic Map5172.13RGD
Genethon Genetic Map5172.6UniSTS
TNG Radiation Hybrid Map577845.0UniSTS
deCODE Assembly Map5174.17UniSTS
Stanford-G3 RH Map55901.0UniSTS
GeneMap99-GB4 RH Map5624.94UniSTS
Whitehead-RH Map5526.1UniSTS
NCBI RH Map5973.0UniSTS
GeneMap99-G3 RH Map55989.0UniSTS
RH77908  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,673,342 - 167,673,466UniSTSGRCh37
Build 365167,605,920 - 167,606,044RGDNCBI36
Celera5163,708,710 - 163,708,834RGD
Cytogenetic Map5q34UniSTS
HuRef5162,773,315 - 162,773,439UniSTS
GeneMap99-GB4 RH Map5626.62UniSTS
A004A45  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,180,813 - 167,181,027UniSTSGRCh37
Build 365167,113,391 - 167,113,605RGDNCBI36
Celera5163,216,785 - 163,216,999RGD
Cytogenetic Map5q34UniSTS
HuRef5162,281,238 - 162,281,452UniSTS
GeneMap99-GB4 RH Map5626.72UniSTS
NCBI RH Map5973.0UniSTS
WI-22532  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,658,520 - 167,658,773UniSTSGRCh37
Build 365167,591,098 - 167,591,351RGDNCBI36
Celera5163,693,889 - 163,694,142RGD
Cytogenetic Map5q34UniSTS
HuRef5162,758,555 - 162,758,808UniSTS
GeneMap99-GB4 RH Map5626.72UniSTS
Whitehead-RH Map5529.2UniSTS
D5S2458  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,626,652 - 167,626,881UniSTSGRCh37
Build 365167,559,230 - 167,559,459RGDNCBI36
Celera5163,661,937 - 163,662,166RGD
Cytogenetic Map5q34UniSTS
HuRef5162,726,557 - 162,726,786UniSTS
Whitehead-RH Map5529.2UniSTS
Whitehead-YAC Contig Map5 UniSTS
NCBI RH Map5973.0UniSTS
D5S805  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375166,876,482 - 166,876,638UniSTSGRCh37
Build 365166,809,060 - 166,809,216RGDNCBI36
Celera5162,912,402 - 162,912,550RGD
Cytogenetic Map5q34UniSTS
HuRef5161,976,875 - 161,977,034UniSTS
TNG Radiation Hybrid Map577788.0UniSTS
Whitehead-YAC Contig Map5 UniSTS
G43625  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,557,097 - 167,557,390UniSTSGRCh37
Build 365167,489,675 - 167,489,968RGDNCBI36
Celera5163,592,438 - 163,592,731RGD
Cytogenetic Map5q34UniSTS
HuRef5162,656,989 - 162,657,282UniSTS
SHGC-68636  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,550,400 - 167,550,493UniSTSGRCh37
Build 365167,482,978 - 167,483,071RGDNCBI36
Celera5163,585,742 - 163,585,835RGD
Cytogenetic Map5q34UniSTS
HuRef5162,650,293 - 162,650,386UniSTS
TNG Radiation Hybrid Map578205.0UniSTS
SHGC-78928  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,009,231 - 167,009,533UniSTSGRCh37
Build 365166,941,809 - 166,942,111RGDNCBI36
Celera5163,045,219 - 163,045,521RGD
Cytogenetic Map5q34UniSTS
HuRef5162,109,769 - 162,110,071UniSTS
TNG Radiation Hybrid Map577880.0UniSTS
SHGC-84519  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375166,835,083 - 166,835,376UniSTSGRCh37
Build 365166,767,661 - 166,767,954RGDNCBI36
Celera5162,871,212 - 162,871,505RGD
Cytogenetic Map5q34UniSTS
HuRef5161,935,709 - 161,936,002UniSTS
TNG Radiation Hybrid Map577750.0UniSTS
RH122050  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,485,258 - 167,485,552UniSTSGRCh37
Build 365167,417,836 - 167,418,130RGDNCBI36
Celera5163,520,620 - 163,520,914RGD
Cytogenetic Map5q34UniSTS
HuRef5162,585,161 - 162,585,455UniSTS
TNG Radiation Hybrid Map578164.0UniSTS
SHGC-110807  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,241,599 - 167,241,891UniSTSGRCh37
Build 365167,174,177 - 167,174,469RGDNCBI36
Celera5163,277,688 - 163,277,980RGD
Cytogenetic Map5q34UniSTS
HuRef5162,342,029 - 162,342,321UniSTS
TNG Radiation Hybrid Map578015.0UniSTS
SHGC-111408  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,061,569 - 167,061,865UniSTSGRCh37
Build 365166,994,147 - 166,994,443RGDNCBI36
Celera5163,097,560 - 163,097,856RGD
Cytogenetic Map5q34UniSTS
HuRef5162,162,005 - 162,162,301UniSTS
TNG Radiation Hybrid Map577872.0UniSTS
SHGC-107168  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,164,787 - 167,165,066UniSTSGRCh37
Build 365167,097,365 - 167,097,644RGDNCBI36
Celera5163,200,764 - 163,201,043RGD
Cytogenetic Map5q34UniSTS
HuRef5162,265,207 - 162,265,486UniSTS
TNG Radiation Hybrid Map577956.0UniSTS
SHGC-144555  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375166,941,028 - 166,941,314UniSTSGRCh37
Build 365166,873,606 - 166,873,892RGDNCBI36
Celera5162,976,990 - 162,977,276RGD
Cytogenetic Map5q34UniSTS
HuRef5162,041,458 - 162,041,744UniSTS
TNG Radiation Hybrid Map577817.0UniSTS
SHGC-145647  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375166,987,798 - 166,988,076UniSTSGRCh37
Build 365166,920,376 - 166,920,654RGDNCBI36
Celera5163,023,772 - 163,024,040RGD
Cytogenetic Map5q34UniSTS
HuRef5162,088,323 - 162,088,591UniSTS
TNG Radiation Hybrid Map577838.0UniSTS
SHGC-147036  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,033,586 - 167,033,935UniSTSGRCh37
Build 365166,966,164 - 166,966,513RGDNCBI36
Celera5163,069,580 - 163,069,929RGD
Cytogenetic Map5q34UniSTS
HuRef5162,134,024 - 162,134,373UniSTS
TNG Radiation Hybrid Map577872.0UniSTS
RH78971  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,657,935 - 167,658,053UniSTSGRCh37
Build 365167,590,513 - 167,590,631RGDNCBI36
Celera5163,693,304 - 163,693,422RGD
Cytogenetic Map5q34UniSTS
HuRef5162,757,970 - 162,758,088UniSTS
GeneMap99-GB4 RH Map5626.62UniSTS
bac5967T  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375166,724,261 - 166,724,407UniSTSGRCh37
Build 365166,656,839 - 166,656,985RGDNCBI36
Celera5162,762,920 - 162,763,066RGD
Cytogenetic Map5q34UniSTS
HuRef5161,824,841 - 161,824,987UniSTS
bac5977T  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375166,980,280 - 166,980,472UniSTSGRCh37
Build 365166,912,858 - 166,913,050RGDNCBI36
Celera5163,016,250 - 163,016,442RGD
Cytogenetic Map5q34UniSTS
HuRef5162,080,800 - 162,080,992UniSTS
bac5992T  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,344,077 - 167,344,254UniSTSGRCh37
Build 365167,276,655 - 167,276,832RGDNCBI36
Celera5163,379,484 - 163,379,661RGD
Cytogenetic Map5q34UniSTS
HuRef5162,444,123 - 162,444,300UniSTS
SHGC-132122  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,421,536 - 167,421,867UniSTSGRCh37
Build 365167,354,114 - 167,354,445RGDNCBI36
Celera5163,456,943 - 163,457,274RGD
Cytogenetic Map5q34UniSTS
HuRef5162,521,437 - 162,521,768UniSTS
TNG Radiation Hybrid Map578111.0UniSTS
SHGC-154041  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,421,259 - 167,421,558UniSTSGRCh37
Build 365167,353,837 - 167,354,136RGDNCBI36
Celera5163,456,666 - 163,456,965RGD
Cytogenetic Map5q34UniSTS
HuRef5162,521,160 - 162,521,459UniSTS
TNG Radiation Hybrid Map578099.0UniSTS
WI-3815  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,304,235 - 167,304,442UniSTSGRCh37
Build 365167,236,813 - 167,237,020RGDNCBI36
Celera5163,339,862 - 163,340,069RGD
Cytogenetic Map5q34UniSTS
HuRef5162,404,517 - 162,404,724UniSTS
Whitehead-RH Map5529.2UniSTS
L18086  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,321,143 - 167,321,256UniSTSGRCh37
Build 365167,253,721 - 167,253,834RGDNCBI36
Celera5163,356,766 - 163,356,879RGD
Cytogenetic Map5q34UniSTS
HuRef5162,421,419 - 162,421,532UniSTS
CHLC.GCT10G10  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,474,827 - 167,474,944UniSTSGRCh37
Build 365167,407,405 - 167,407,522RGDNCBI36
Celera5163,510,189 - 163,510,306RGD
Cytogenetic Map5q34UniSTS
HuRef5162,574,730 - 162,574,847UniSTS
Whitehead-YAC Contig Map5 UniSTS
SHGC-13752  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,256,711 - 167,256,853UniSTSGRCh37
Build 365167,189,289 - 167,189,431RGDNCBI36
Celera5163,292,818 - 163,292,960RGD
Cytogenetic Map5q34UniSTS
HuRef5162,357,145 - 162,357,287UniSTS
Stanford-G3 RH Map55942.0UniSTS
G19199  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,253,848 - 167,254,072UniSTSGRCh37
Build 365167,186,426 - 167,186,650RGDNCBI36
Celera5163,289,952 - 163,290,176RGD
Cytogenetic Map5q34UniSTS
HuRef5162,354,280 - 162,354,504UniSTS
G28629  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,270,699 - 167,270,798UniSTSGRCh37
Build 365167,203,277 - 167,203,376RGDNCBI36
Celera5163,306,799 - 163,306,898RGD
Cytogenetic Map5q34UniSTS
HuRef5162,371,129 - 162,371,228UniSTS
D5S1888  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,261,197 - 167,261,358UniSTSGRCh37
Build 365167,193,775 - 167,193,936RGDNCBI36
Celera5163,297,298 - 163,297,459RGD
Cytogenetic Map5q34UniSTS
HuRef5162,361,627 - 162,361,788UniSTS
Whitehead-RH Map5529.2UniSTS
Whitehead-YAC Contig Map5 UniSTS
NCBI RH Map5973.0UniSTS
G16914  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,685,560 - 167,685,659UniSTSGRCh37
Build 365167,618,138 - 167,618,237RGDNCBI36
Celera5163,720,932 - 163,721,031RGD
Cytogenetic Map5q34UniSTS
HuRef5162,785,501 - 162,785,600UniSTS
WI-22163  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,179,410 - 167,179,588UniSTSGRCh37
Build 365167,111,988 - 167,112,166RGDNCBI36
Celera5163,215,382 - 163,215,560RGD
Cytogenetic Map5q34UniSTS
HuRef5162,279,835 - 162,280,013UniSTS
GeneMap99-GB4 RH Map5626.72UniSTS
Whitehead-RH Map5527.7UniSTS
NCBI RH Map5973.0UniSTS
G18151  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,426,680 - 167,426,964UniSTSGRCh37
Build 365167,359,258 - 167,359,542RGDNCBI36
Celera5163,462,099 - 163,462,383RGD
Cytogenetic Map5q34UniSTS
HuRef5162,526,593 - 162,526,877UniSTS
SHGC-13056  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,421,554 - 167,421,825UniSTSGRCh37
Build 365167,354,132 - 167,354,403RGDNCBI36
Celera5163,456,961 - 163,457,232RGD
Cytogenetic Map5q34UniSTS
HuRef5162,521,455 - 162,521,726UniSTS
Stanford-G3 RH Map55936.0UniSTS
SHGC-23892  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,470,527 - 167,470,660UniSTSGRCh37
Build 365167,403,105 - 167,403,238RGDNCBI36
Celera5163,505,889 - 163,506,022RGD
Cytogenetic Map5q34UniSTS
HuRef5162,570,430 - 162,570,563UniSTS
TNG Radiation Hybrid Map578176.0UniSTS
ODZ2_3320  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375167,689,112 - 167,689,899UniSTSGRCh37
Build 365167,621,690 - 167,622,477RGDNCBI36
Celera5163,724,484 - 163,725,271RGD
HuRef5162,789,053 - 162,789,840UniSTS
RH11035  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q34UniSTS
HuRef5162,790,513 - 162,790,693UniSTS
GeneMap99-GB4 RH Map5626.72UniSTS
NCBI RH Map5973.0UniSTS
D5S496  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q34UniSTS
TNG Radiation Hybrid Map577845.0UniSTS
Stanford-G3 RH Map55901.0UniSTS
NCBI RH Map5973.0UniSTS
GeneMap99-G3 RH Map55989.0UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3224
Count of miRNA genes:956
Interacting mature miRNAs:1168
Transcripts:ENST00000403607, ENST00000517586, ENST00000517941, ENST00000518659, ENST00000518693, ENST00000519204, ENST00000520393, ENST00000520394, ENST00000521126, ENST00000522488, ENST00000545108
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage
High
Medium 10 555 19 8 5 7 427 303 577 26 38 67 7 364
Low 500 444 903 275 221 190 1827 354 2729 153 887 663 89 125 1004
Below cutoff 1814 1710 743 293 1192 220 1973 1463 403 177 464 793 76 1 1068 1338

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001080428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001122679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001368145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001368146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001395460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005265950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005265952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006714897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011534604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB032953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC008464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC008601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC008607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC008634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC008637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC008642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC008705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC008708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC011369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC011384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC026689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC026729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC091819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC091820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC093304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC113372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK056053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK302302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL137500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF950845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ774782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX648178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR936703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HE578282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HE578283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HE610428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN857072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN857073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN857074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN857075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN857076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC877165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC877176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF458051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF458054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000517586
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5167,821,068 - 167,952,655 (+)Ensembl
RefSeq Acc Id: ENST00000517941
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5168,226,248 - 168,241,112 (+)Ensembl
RefSeq Acc Id: ENST00000518659   ⟹   ENSP00000429430
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5167,284,799 - 168,262,996 (+)Ensembl
RefSeq Acc Id: ENST00000518693
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5167,934,862 - 168,047,462 (+)Ensembl
RefSeq Acc Id: ENST00000519204   ⟹   ENSP00000428964
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5167,754,936 - 168,264,157 (+)Ensembl
RefSeq Acc Id: ENST00000520393
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5167,573,974 - 167,993,014 (+)Ensembl
RefSeq Acc Id: ENST00000520394   ⟹   ENSP00000427874
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5167,755,003 - 168,263,185 (+)Ensembl
RefSeq Acc Id: ENST00000521126
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5168,162,694 - 168,190,874 (+)Ensembl
RefSeq Acc Id: ENST00000522488
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5167,952,375 - 167,993,043 (+)Ensembl
RefSeq Acc Id: NM_001080428   ⟹   NP_001073897
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385167,754,929 - 168,264,157 (+)NCBI
Build 365167,114,519 - 167,623,740 (+)NCBI Archive
CHM1_15166,614,362 - 167,124,193 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001122679   ⟹   NP_001116151
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385167,073,242 - 168,264,157 (+)NCBI
GRCh375166,406,083 - 167,691,162 (+)NCBI
Celera5162,750,499 - 163,726,534 (+)RGD
HuRef5161,812,425 - 162,791,103 (+)ENTREZGENE
CHM1_15166,144,311 - 167,124,193 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001368145   ⟹   NP_001355074
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385167,573,659 - 168,264,157 (+)NCBI
RefSeq Acc Id: NM_001368146   ⟹   NP_001355075
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385167,573,659 - 168,264,157 (+)NCBI
RefSeq Acc Id: XM_005265950   ⟹   XP_005266007
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385166,979,066 - 168,264,151 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005265952   ⟹   XP_005266009
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385167,934,862 - 168,263,778 (+)NCBI
GRCh375166,406,083 - 167,691,162 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006714897   ⟹   XP_006714960
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385166,979,066 - 168,264,159 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011534604   ⟹   XP_011532906
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385166,979,066 - 168,264,159 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017009660   ⟹   XP_016865149
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385166,979,066 - 168,264,159 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017009661   ⟹   XP_016865150
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385166,979,066 - 168,264,159 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017009662   ⟹   XP_016865151
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385166,979,066 - 168,263,778 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017009663   ⟹   XP_016865152
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385167,752,292 - 168,263,778 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017009664   ⟹   XP_016865153
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385167,754,936 - 168,263,778 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017009665   ⟹   XP_016865154
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385167,573,974 - 168,263,778 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017009668   ⟹   XP_016865157
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385167,819,113 - 168,263,778 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017009669   ⟹   XP_016865158
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385167,720,013 - 168,263,778 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001116151   ⟸   NM_001122679
- Peptide Label: isoform 1
- Sequence:
RefSeq Acc Id: NP_001073897   ⟸   NM_001080428
- Peptide Label: isoform 2
- UniProtKB: Q9NT68 (UniProtKB/Swiss-Prot),   F8VNQ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005266007   ⟸   XM_005265950
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005266009   ⟸   XM_005265952
- Peptide Label: isoform X13
- Sequence:
RefSeq Acc Id: XP_006714960   ⟸   XM_006714897
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_011532906   ⟸   XM_011534604
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_016865149   ⟸   XM_017009660
- Peptide Label: isoform X1
- UniProtKB: Q9NT68 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016865150   ⟸   XM_017009661
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_016865151   ⟸   XM_017009662
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_016865154   ⟸   XM_017009665
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_016865158   ⟸   XM_017009669
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_016865152   ⟸   XM_017009663
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_016865153   ⟸   XM_017009664
- Peptide Label: isoform X8
- UniProtKB: G3V106 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016865157   ⟸   XM_017009668
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: NP_001355074   ⟸   NM_001368145
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001355075   ⟸   NM_001368146
- Peptide Label: isoform 4
RefSeq Acc Id: ENSP00000429430   ⟸   ENST00000518659
RefSeq Acc Id: ENSP00000428964   ⟸   ENST00000519204
RefSeq Acc Id: ENSP00000427874   ⟸   ENST00000520394
Protein Domains
EGF-like   Teneurin N-terminal

Promoters
RGD ID:6803414
Promoter ID:HG_KWN:51727
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:UC010JJE.1
Position:
Human AssemblyChrPosition (strand)Source
Build 365167,483,771 - 167,484,271 (+)MPROMDB
RGD ID:6871486
Promoter ID:EPDNEW_H8908
Type:initiation region
Name:TENM2_1
Description:teneurin transmembrane protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385167,754,929 - 167,754,989EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5q32-35.3(chr5:149714592-181272151)x3 copy number gain See cases [RCV000051863] Chr5:149714592..181272151 [GRCh38]
Chr5:149094155..180699152 [GRCh37]
Chr5:149074348..180631758 [NCBI36]
Chr5:5q32-35.3
pathogenic
GRCh38/hg38 5q33.3-35.3(chr5:160029980-181269805)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051865]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051865]|See cases [RCV000051865] Chr5:160029980..181269805 [GRCh38]
Chr5:159456987..180696806 [GRCh37]
Chr5:159389565..180629412 [NCBI36]
Chr5:5q33.3-35.3
pathogenic
GRCh38/hg38 5q34-35.1(chr5:166371405-171390034)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052148]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052148]|See cases [RCV000052148] Chr5:166371405..171390034 [GRCh38]
Chr5:165798410..170817038 [GRCh37]
Chr5:165730988..170749643 [NCBI36]
Chr5:5q34-35.1
pathogenic
NM_001122679.1(TENM2):c.247G>A (p.Glu83Lys) single nucleotide variant Malignant melanoma [RCV000066825] Chr5:167375218 [GRCh38]
Chr5:166802223 [GRCh37]
Chr5:166734801 [NCBI36]
Chr5:5q34
not provided
NM_001122679.1(TENM2):c.3261C>T (p.Leu1087=) single nucleotide variant Malignant melanoma [RCV000066826] Chr5:168199989 [GRCh38]
Chr5:167626994 [GRCh37]
Chr5:167559572 [NCBI36]
Chr5:5q34
not provided
NM_001122679.1(TENM2):c.3350G>A (p.Trp1117Ter) single nucleotide variant Malignant melanoma [RCV000066827] Chr5:168200078 [GRCh38]
Chr5:167627083 [GRCh37]
Chr5:167559661 [NCBI36]
Chr5:5q34
not provided
NM_001122679.1(TENM2):c.3351G>A (p.Trp1117Ter) single nucleotide variant Malignant melanoma [RCV000066828] Chr5:168200079 [GRCh38]
Chr5:167627084 [GRCh37]
Chr5:167559662 [NCBI36]
Chr5:5q34
not provided
NM_001122679.1(TENM2):c.3492C>T (p.Pro1164=) single nucleotide variant Malignant melanoma [RCV000066829] Chr5:168203777 [GRCh38]
Chr5:167630782 [GRCh37]
Chr5:167563360 [NCBI36]
Chr5:5q34
not provided
NM_001122679.1(TENM2):c.7689C>T (p.Ile2563=) single nucleotide variant Malignant melanoma [RCV000066830] Chr5:168262201 [GRCh38]
Chr5:167689206 [GRCh37]
Chr5:167621784 [NCBI36]
Chr5:5q34
not provided
NC_000005.10:g.166992274G>T single nucleotide variant Lung cancer [RCV000095545] Chr5:166992274 [GRCh38]
Chr5:166419279 [GRCh37]
Chr5:5q34
uncertain significance
NM_001122679.1(TENM2):c.502+8283G>T single nucleotide variant Lung cancer [RCV000095546] Chr5:167383756 [GRCh38]
Chr5:166810761 [GRCh37]
Chr5:5q34
uncertain significance
NM_001122679.1(TENM2):c.502+54243C>T single nucleotide variant Lung cancer [RCV000095547] Chr5:167429716 [GRCh38]
Chr5:166856721 [GRCh37]
Chr5:5q34
uncertain significance
GRCh38/hg38 5q33.3-35.3(chr5:156825512-181269805)x3 copy number gain See cases [RCV000133847] Chr5:156825512..181269805 [GRCh38]
Chr5:156252523..180696806 [GRCh37]
Chr5:156185101..180629412 [NCBI36]
Chr5:5q33.3-35.3
pathogenic
GRCh38/hg38 5q34-35.3(chr5:164386701-181269805)x3 copy number gain See cases [RCV000135546] Chr5:164386701..181269805 [GRCh38]
Chr5:163813707..180696806 [GRCh37]
Chr5:163746285..180629412 [NCBI36]
Chr5:5q34-35.3
pathogenic
GRCh38/hg38 5q34-35.1(chr5:168234662-169027391)x3 copy number gain See cases [RCV000137176] Chr5:168234662..169027391 [GRCh38]
Chr5:167661667..168454396 [GRCh37]
Chr5:167594245..168386974 [NCBI36]
Chr5:5q34-35.1
likely benign|uncertain significance
GRCh38/hg38 5q34(chr5:167061697-167390406)x1 copy number loss See cases [RCV000138174] Chr5:167061697..167390406 [GRCh38]
Chr5:166488702..166817411 [GRCh37]
Chr5:166421280..166749989 [NCBI36]
Chr5:5q34
likely benign|uncertain significance
GRCh38/hg38 5q34(chr5:167317403-167863954)x3 copy number gain See cases [RCV000143323] Chr5:167317403..167863954 [GRCh38]
Chr5:166744408..167290959 [GRCh37]
Chr5:166676986..167223537 [NCBI36]
Chr5:5q34
likely benign
GRCh38/hg38 5q33.1-34(chr5:152761187-167248053)x1 copy number loss See cases [RCV000052144] Chr5:152761187..167248053 [GRCh38]
Chr5:152140747..166675058 [GRCh37]
Chr5:152120940..166607636 [NCBI36]
Chr5:5q33.1-34
pathogenic
GRCh37/hg19 5q33.2-35.1(chr5:154886174-169757448)x1 copy number loss See cases [RCV000240059] Chr5:154886174..169757448 [GRCh37]
Chr5:5q33.2-35.1
pathogenic
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3 copy number gain not provided [RCV000487658] Chr5:94844077..178830410 [GRCh37]
Chr5:5q15-35.3
likely benign
GRCh37/hg19 5q34-35.1(chr5:164207156-172799124)x1 copy number loss See cases [RCV000447112] Chr5:164207156..172799124 [GRCh37]
Chr5:5q34-35.1
pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3
pathogenic
NM_001080428.3(TENM2):c.614-5_614-4dup duplication not specified [RCV000455684] Chr5:168062044..168062045 [GRCh38]
Chr5:167489049..167489050 [GRCh37]
Chr5:5q34
benign
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
NM_001080428.3(TENM2):c.1118-1G>T single nucleotide variant not provided [RCV000513522] Chr5:168118291 [GRCh38]
Chr5:167545296 [GRCh37]
Chr5:5q34
uncertain significance
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q33.2-35.3(chr5:155344802-180693344)x3 copy number gain not provided [RCV000745284] Chr5:155344802..180693344 [GRCh37]
Chr5:5q33.2-35.3
pathogenic
GRCh37/hg19 5q34(chr5:167210684-167907762)x3 copy number gain not provided [RCV000745326] Chr5:167210684..167907762 [GRCh37]
Chr5:5q34
likely benign
GRCh37/hg19 5q34(chr5:167472891-167496863)x3 copy number gain not provided [RCV000745327] Chr5:167472891..167496863 [GRCh37]
Chr5:5q34
benign
NM_001080428.3(TENM2):c.3448C>A (p.Leu1150Met) single nucleotide variant Esophageal atresia [RCV000984689] Chr5:168216854 [GRCh38]
Chr5:167643859 [GRCh37]
Chr5:5q34
uncertain significance
NM_001122679.2(TENM2):c.2542+10C>T single nucleotide variant not provided [RCV000917316] Chr5:168162767 [GRCh38]
Chr5:167589772 [GRCh37]
Chr5:5q34
likely benign
GRCh37/hg19 5q33.3-35.1(chr5:156597181-171166353)x3 copy number gain not provided [RCV000845588] Chr5:156597181..171166353 [GRCh37]
Chr5:5q33.3-35.1
pathogenic
NM_001122679.2(TENM2):c.5982C>T (p.Asp1994=) single nucleotide variant not provided [RCV000962132] Chr5:168246948 [GRCh38]
Chr5:167673953 [GRCh37]
Chr5:5q34
benign
GRCh37/hg19 5q34(chr5:167397612-167763698)x3 copy number gain not provided [RCV001007547] Chr5:167397612..167763698 [GRCh37]
Chr5:5q34
uncertain significance
GRCh37/hg19 5q34-35.2(chr5:166421173-173324843)x1 copy number loss Atrial septal defect 7 with or without atrioventricular conduction defects [RCV000853560] Chr5:166421173..173324843 [GRCh37]
Chr5:5q34-35.2
pathogenic
GRCh37/hg19 5q33.3-35.1(chr5:156347980-169959880)x1 copy number loss not provided [RCV001005746] Chr5:156347980..169959880 [GRCh37]
Chr5:5q33.3-35.1
pathogenic
NM_201384.3(PLEC):c.7029G>A (p.Ala2343=) single nucleotide variant not provided [RCV001721829] Chr5:168262399 [GRCh38]
Chr5:167689404 [GRCh37]
Chr5:5q34
benign
GRCh37/hg19 5q34(chr5:166682781-167626696)x1 copy number loss not provided [RCV001259926] Chr5:166682781..167626696 [GRCh37]
Chr5:5q34
uncertain significance
GRCh37/hg19 5q34-35.1(chr5:166378793-170174830)x1 copy number loss not provided [RCV001259927] Chr5:166378793..170174830 [GRCh37]
Chr5:5q34-35.1
likely pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:29943 AgrOrtholog
COSMIC TENM2 COSMIC
Ensembl Genes ENSG00000145934 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000427874 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000428964 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000429430 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000518659 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000519204 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000520394 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000145934 GTEx
HGNC ID HGNC:29943 ENTREZGENE
Human Proteome Map TENM2 Human Proteome Map
InterPro 6-blade_b-propeller_TolB-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CarboxyPept-like_regulatory UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IPR006530 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Quino_amine_DH_bsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhs_assc_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ten-2/3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ten_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tox-GHH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:57451 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 57451 ENTREZGENE
OMIM 610119 OMIM
PANTHER PTHR11219:SF8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ten_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tox-GHH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134909677 PharmGKB
PROSITE EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TENEURIN_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49464 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50969 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs Rhs_assc_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  YD_repeat_2x UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F8VNQ3 ENTREZGENE, UniProtKB/TrEMBL
  G3V106 ENTREZGENE, UniProtKB/TrEMBL
  Q9NT68 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q9ULU2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-09 TENM2  teneurin transmembrane protein 2  ODZ2  odz, odd Oz/ten-m homolog 2 (Drosophila)  Symbol and/or name change 5135510 APPROVED