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Gene: CDC37 (cell division cycle 37) Homo sapiens
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Symbol: CDC37
Name: cell division cycle 37
Description: The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDC37 (cell division cycle 37, S. cerevisiae, homolog); CDC37 cell division cycle 37 homolog; cell division cycle 37 homolog; hsp90 chaperone protein kinase-targeting subunit; hsp90 co-chaperone Cdc37; P50CDC37
Orthologs:
Mus musculus (house mouse) : Cdc37 (cell division cycle 37)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdc37 (cell division cycle 37)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc37 (cell division cycle 37)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC37 (cell division cycle 37)
Canis lupus familiaris (dog) : CDC37 (cell division cycle 37)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc37 (cell division cycle 37)
Sus scrofa (pig) : CDC37 (cell division cycle 37)
more info ...
Related Pseudogenes: CDC37P1   CDC37P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,391,128 - 10,403,568 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,501,809 - 10,514,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,362,809 - 10,375,271 (-)NCBINCBI36hg18NCBI36
Build 341910,362,808 - 10,375,271NCBI
Celera1910,396,515 - 10,408,977 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1910,081,863 - 10,094,337 (-)NCBIHuRef
CHM1_11910,502,536 - 10,515,003 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDC37
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732258
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.