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Gene: Kpna2 (karyopherin (importin) alpha 2) Mus musculus
Symbol: Kpna2
Name: karyopherin (importin) alpha 2
Description: Exhibits nuclear import signal receptor activity and repressing transcription factor binding activity. Involved in entry of viral genome into host nucleus through nuclear pore complex via importin; positive regulation of viral life cycle; and protein import into nucleus. Localizes to the cytoplasmic stress granule. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human KPNA2 (karyopherin subunit alpha 2); PARTICIPATES IN influenza A pathway; INTERACTS WITH (S)-amphetamine; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410044B12Rik; importin alpha 1; importin alpha P1; importin subunit alpha-1; importin subunit alpha-2; IPOA1; karyopherin subunit alpha-2; m-importin-alpha-P1; MGC91246; pendulin; pore targeting complex 58 kDa subunit; PTAC58; RAG cohort protein 1; Rch1; SRP1-alpha
Homo sapiens (human) : KPNA2 (karyopherin subunit alpha 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kpna2 (karyopherin subunit alpha 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kpna2 (karyopherin subunit alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : KPNA2 (karyopherin subunit alpha 2)
Canis lupus familiaris (dog) : KPNA2 (karyopherin subunit alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kpna2 (karyopherin subunit alpha 2)
Sus scrofa (pig) : KPNA2 (karyopherin subunit alpha 2)
Chlorocebus sabaeus (green monkey) : KPNA2 (karyopherin subunit alpha 2)
Heterocephalus glaber (naked mole-rat) : Kpna2 (karyopherin subunit alpha 2)
more info ...
Related Pseudogenes: Gm10184   Gm10259   Gm12919   Gm13310   Gm16436   Gm18542   Gm18581   Gm4991   Gm5832   Gm9314   Kpna2-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl11106,988,629 - 106,999,541 (-)Ensembl
GRCm3811106,988,629 - 106,999,525 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711106,849,943 - 106,860,839 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611106,804,719 - 106,815,615 (-)NCBImm8
Celera11118,719,792 - 118,733,297 (-)NCBICelera
Cytogenetic Map11E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kpna2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732238
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.