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Gene: Kpna2 (karyopherin (importin) alpha 2) Mus musculus
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Symbol: Kpna2
Name: karyopherin (importin) alpha 2
Description: Exhibits nuclear import signal receptor activity and repressing transcription factor binding activity. Involved in entry of viral genome into host nucleus through nuclear pore complex via importin; positive regulation of viral life cycle; and protein import into nucleus. Localizes to the cytoplasmic stress granule. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human KPNA2 (karyopherin subunit alpha 2); PARTICIPATES IN influenza A pathway; INTERACTS WITH (S)-amphetamine; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410044B12Rik; importin alpha 1; importin alpha P1; importin subunit alpha-1; importin subunit alpha-2; IPOA1; karyopherin subunit alpha-2; m-importin-alpha-P1; MGC91246; pendulin; pore targeting complex 58 kDa subunit; PTAC58; RAG cohort protein 1; Rch1; SRP1-alpha
Orthologs:
Homo sapiens (human) : KPNA2 (karyopherin subunit alpha 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kpna2 (karyopherin subunit alpha 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kpna2 (karyopherin subunit alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : KPNA2 (karyopherin subunit alpha 2)
Canis lupus familiaris (dog) : KPNA2 (karyopherin subunit alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kpna2 (karyopherin subunit alpha 2)
Sus scrofa (pig) : KPNA2 (karyopherin subunit alpha 2)
Chlorocebus sabaeus (green monkey) : KPNA2 (karyopherin subunit alpha 2)
Heterocephalus glaber (naked mole-rat) : Kpna2 (karyopherin subunit alpha 2)
more info ...
Related Pseudogenes: Gm10184   Gm10259   Gm12919   Gm13310   Gm16436   Gm18542   Gm18581   Gm4991   Gm5832   Gm9314   Kpna2-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl11106,988,629 - 106,999,541 (-)Ensembl
GRCm3811106,988,629 - 106,999,525 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711106,849,943 - 106,860,839 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611106,804,719 - 106,815,615 (-)NCBImm8
Celera11118,719,792 - 118,733,297 (-)NCBICelera
Cytogenetic Map11E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kpna2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732238
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.