Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SLC36A1 mRNA] | CTD | PMID:31150632 | 1,2-dichloroethane | increases expression | EXP | | 6480464 | ethylene dichloride results in increased expression of SLC36A1 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SLC36A1 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SLC36A1 mRNA | CTD | PMID:26290441 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SLC36A1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SLC36A1 mRNA | CTD | PMID:21570461 and PMID:26377647 | 2-hydroxypropanoic acid | decreases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SLC36A1 mRNA | CTD | PMID:30851411 | 3,4-methylenedioxymethamphetamine | decreases methylation | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased methylation of SLC36A1 promoter | CTD | PMID:26251327 | 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of SLC36A1 mRNA | CTD | PMID:26251327 | 6-propyl-2-thiouracil | decreases expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of SLC36A1 mRNA | CTD | PMID:24780913 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of SLC36A1 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | increases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of SLC36A1 mRNA | CTD | PMID:15498508 and PMID:33167477 | ammonium chloride | affects expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of SLC36A1 mRNA | CTD | PMID:16483693 | atrazine | decreases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of SLC36A1 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | affects methylation | ISO | SLC36A1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SLC36A1 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of SLC36A1 mRNA | CTD | PMID:32234424 | bisphenol A | decreases expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of SLC36A1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SLC36A1 mRNA | CTD | PMID:32156529 | CGP 52608 | multiple interactions | ISO | SLC36A1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SLC36A1 gene] | CTD | PMID:28238834 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SLC36A1 gene | CTD | PMID:20938992 | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of SLC36A1 mRNA | CTD | PMID:28472532 | cyclosporin A | increases methylation | ISO | SLC36A1 (Homo sapiens) | 6480464 | Cyclosporine results in increased methylation of SLC36A1 promoter | CTD | PMID:27989131 | dextran sulfate | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC36A1 mRNA | CTD | PMID:29950665 | dibenzo[a,l]pyrene | decreases expression | EXP | | 6480464 | dibenzo(a and l)pyrene results in decreased expression of SLC36A1 mRNA | CTD | PMID:25908611 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of SLC36A1 mRNA | CTD | PMID:17361019 and PMID:21266533 | dibutyl phthalate | affects expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate affects the expression of SLC36A1 mRNA | CTD | PMID:30934153 | dicrotophos | increases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of SLC36A1 mRNA | CTD | PMID:28302478 | dioxygen | decreases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of SLC36A1 mRNA | CTD | PMID:26516004 | EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor | increases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Angiotensin-Converting Enzyme Inhibitors results in increased expression of SLC36A1 mRNA | CTD | PMID:25534429 | endosulfan | increases expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of SLC36A1 mRNA | CTD | PMID:29391264 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of SLC36A1 mRNA | CTD | PMID:35436446 | ethanol | decreases expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | Ethanol results in decreased expression of SLC36A1 mRNA | CTD | PMID:20655511 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of SLC36A1 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SLC36A1 gene | CTD | PMID:20938992 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of SLC36A1 mRNA | CTD | PMID:25629700 | gentamycin | increases expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of SLC36A1 mRNA | CTD | PMID:33387578 | glycine betaine | increases uptake | EXP | | 6480464 | SLC36A1 protein results in increased uptake of Betaine | CTD | PMID:18845132 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SLC36A1 gene | CTD | PMID:20938992 | methyl methanesulfonate | increases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of SLC36A1 mRNA | CTD | PMID:23649840 | nickel atom | increases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Nickel results in increased expression of SLC36A1 mRNA | CTD | PMID:25583101 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SLC36A1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SLC36A1 mRNA | CTD | PMID:22230336 and PMID:29067470 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of SLC36A1 mRNA | CTD | PMID:20813756 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of SLC36A1 mRNA | CTD | PMID:28903501 | rac-lactic acid | decreases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SLC36A1 mRNA | CTD | PMID:30851411 | sevoflurane | decreases methylation | EXP | | 6480464 | Sevoflurane results in decreased methylation of SLC36A1 mRNA | CTD | PMID:35249202 | sodium dichromate | decreases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | sodium bichromate results in decreased expression of SLC36A1 mRNA | CTD | PMID:17685462 | tamibarotene | increases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | tamibarotene results in increased expression of SLC36A1 mRNA | CTD | PMID:15498508 | tetrachloromethane | multiple interactions | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SLC36A1 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of SLC36A1 mRNA | CTD | PMID:31919559 | tetrachloromethane | decreases expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of SLC36A1 mRNA | CTD | PMID:31150632 | thapsigargin | decreases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of SLC36A1 mRNA | CTD | PMID:22378314 | titanium dioxide | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC36A1 mRNA | CTD | PMID:29950665 | trichloroethene | increases expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of SLC36A1 mRNA | CTD | PMID:33387578 | tunicamycin | decreases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of SLC36A1 mRNA | CTD | PMID:22378314 | valproic acid | affects expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SLC36A1 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | SLC36A1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SLC36A1 mRNA | CTD | PMID:23179753 more ... | vancomycin | increases expression | EXP | | 6480464 | Vancomycin results in increased expression of SLC36A1 mRNA | CTD | PMID:18930951 | vinclozolin | increases expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of SLC36A1 mRNA | CTD | PMID:22570695 | vinclozolin | decreases expression | ISO | Slc36a1 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of SLC36A1 mRNA | CTD | PMID:23034163 | |