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Gene: HPD (4-hydroxyphenylpyruvate dioxygenase) Homo sapiens
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Symbol: HPD
Name: 4-hydroxyphenylpyruvate dioxygenase
Description: Predicted to have 4-hydroxyphenylpyruvate dioxygenase activity. Predicted to be involved in tyrosine catabolic process. Localizes to the extracellular exosome. Implicated in tyrosinemia type III.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4-HPPD; 4-hydroxyphenylpyruvic acid dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; GLOD3; glyoxalase domain containing 3; HPPDASE; PPD
Orthologs:
Mus musculus (house mouse) : Hpd (4-hydroxyphenylpyruvic acid dioxygenase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hpd (4-hydroxyphenylpyruvate dioxygenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hpd (4-hydroxyphenylpyruvate dioxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : HPD (4-hydroxyphenylpyruvate dioxygenase)
Canis lupus familiaris (dog) : HPD (4-hydroxyphenylpyruvate dioxygenase)
Sus scrofa (pig) : HPD (4-hydroxyphenylpyruvate dioxygenase)
Chlorocebus sabaeus (green monkey) : HPD (4-hydroxyphenylpyruvate dioxygenase)
Heterocephalus glaber (naked mole-rat) : Hpd (4-hydroxyphenylpyruvate dioxygenase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl12121,839,527 - 121,863,596 (-)Ensembl
GRCh3812121,839,527 - 121,888,611 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712122,277,433 - 122,326,517 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612120,761,816 - 120,781,152 (-)NCBINCBI36hg18NCBI36
Build 3412120,740,154 - 120,759,489NCBI
Celera12121,913,690 - 121,962,455 (-)NCBI
Cytogenetic Map12q24.31NCBI
HuRef12119,289,545 - 119,337,791 (-)NCBIHuRef
CHM1_112122,245,145 - 122,294,160 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on HPD
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731782
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.