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Gene: GUCY2F (guanylate cyclase 2F, retinal) Homo sapiens
Symbol: GUCY2F
Name: guanylate cyclase 2F, retinal
Description: Predicted to have guanylate cyclase activity; natriuretic peptide receptor activity; and peptide hormone binding activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to localize to the plasma membrane and rod photoreceptor outer segment.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CYGF; GC-F; guanylate cyclase 2D-like, membrane (retina-specific); guanylate cyclase F; GUC2DL; GUC2F; RETGC-2; retinal guanylyl cyclase 2; rod outer segment membrane guanylate cyclase 2; ROS-GC2
Mus musculus (house mouse) : Gucy2f (guanylate cyclase 2f)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gucy2f (guanylate cyclase 2F)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gucy2f (guanylate cyclase 2F, retinal)
Pan paniscus (bonobo/pygmy chimpanzee) : GUCY2F (guanylate cyclase 2F, retinal)
Canis lupus familiaris (dog) : GUCY2F (guanylate cyclase 2F, retinal)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gucy2f (guanylate cyclase 2F, retinal)
Sus scrofa (pig) : GUCY2F (guanylate cyclase 2F, retinal)
Chlorocebus sabaeus (African green monkey) : GUCY2F (guanylate cyclase 2F, retinal)
Heterocephalus glaber (naked mole-rat) : Gucy2f (guanylate cyclase 2F, retinal)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX109,372,906 - 109,482,086 (-)Ensembl
GRCh38X109,372,061 - 109,482,086 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X108,616,135 - 108,725,285 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X108,502,791 - 108,611,941 (-)NCBINCBI36hg18NCBI36
Build 34X108,422,279 - 108,531,432NCBI
CeleraX109,095,739 - 109,204,892 (-)NCBI
Cytogenetic MapXq22.3-q23NCBI
HuRefX98,238,823 - 98,346,954 (-)NCBIHuRef
CHM1_1X108,527,410 - 108,636,553 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GUCY2F
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731765
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.