Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Bspry (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of BSPRY mRNA] | CTD | PMID:31150632 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BSPRY mRNA | CTD | PMID:22206623 | 1-chloro-2,4-dinitrobenzene | increases expression | EXP | | 6480464 | Dinitrochlorobenzene results in increased expression of BSPRY mRNA | CTD | PMID:18242016 | 17alpha-ethynylestradiol | increases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in increased expression of BSPRY mRNA | CTD | PMID:17557909 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of BSPRY mRNA | CTD | PMID:19484750 | 17beta-estradiol | multiple interactions | ISO | BSPRY (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of BSPRY mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of BSPRY mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of BSPRY mRNA | CTD | PMID:34747641 | 2,4,6-trinitrotoluene | affects expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Trinitrotoluene affects the expression of BSPRY mRNA | CTD | PMID:21346803 | 2,4-dinitrotoluene | affects expression | ISO | Bspry (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of BSPRY mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Bspry (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of BSPRY mRNA | CTD | PMID:21346803 | 2-amino-4,6-dinitrotoluene | affects expression | ISO | Bspry (Rattus norvegicus) | 6480464 | 2-amino-4 and 6-dinitrotoluene affects the expression of BSPRY mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | BSPRY (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of BSPRY mRNA | CTD | PMID:30851411 | 3,7-dihydropurine-6-thione | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Mercaptopurine results in decreased expression of BSPRY mRNA | CTD | PMID:23358152 | 4,4'-sulfonyldiphenol | increases methylation | EXP | | 6480464 | bisphenol S results in increased methylation of BSPRY exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of BSPRY gene | CTD | PMID:31683443 | 4-(ethoxymethylene)-2-phenyloxazol-5-one | increases expression | EXP | | 6480464 | Oxazolone results in increased expression of BSPRY mRNA | CTD | PMID:18242016 | 4-amino-2,6-dinitrotoluene | affects expression | ISO | Bspry (Rattus norvegicus) | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of BSPRY mRNA | CTD | PMID:21346803 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of BSPRY mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of BSPRY mRNA | CTD | PMID:24780913 | acrylamide | increases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of BSPRY mRNA | CTD | PMID:28959563 | ammonium chloride | affects expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of BSPRY mRNA | CTD | PMID:16483693 | atrazine | increases expression | ISO | BSPRY (Homo sapiens) | 6480464 | Atrazine results in increased expression of BSPRY mRNA | CTD | PMID:22378314 | belinostat | multiple interactions | ISO | BSPRY (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BSPRY mRNA | CTD | PMID:27188386 | benzo[a]pyrene | decreases methylation | ISO | BSPRY (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of BSPRY 3' UTR and Benzo(a)pyrene results in decreased methylation of BSPRY promoter | CTD | PMID:27901495 | beta-naphthoflavone | multiple interactions | ISO | Bspry (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BSPRY mRNA | CTD | PMID:18164116 | bisphenol A | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of BSPRY mRNA | CTD | PMID:25181051 more ... | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of BSPRY mRNA | CTD | PMID:32156529 | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of BSPRY mRNA | CTD | PMID:30951980 | butanal | increases expression | ISO | BSPRY (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of BSPRY mRNA | CTD | PMID:26079696 | calcitriol | increases expression | ISO | BSPRY (Homo sapiens) | 6480464 | Calcitriol results in increased expression of BSPRY mRNA | CTD | PMID:26485663 | CGP 52608 | multiple interactions | ISO | BSPRY (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to BSPRY gene] | CTD | PMID:28238834 | chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of BSPRY mRNA | CTD | PMID:23125180 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BSPRY mRNA | CTD | PMID:20938992 | Cuprizon | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of BSPRY mRNA | CTD | PMID:27523638 | dextran sulfate | increases expression | EXP | | 6480464 | Dextran Sulfate results in increased expression of BSPRY mRNA | CTD | PMID:35093514 | diethylstilbestrol | increases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Diethylstilbestrol results in increased expression of BSPRY mRNA | CTD | PMID:21658437 | diuron | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Diuron results in decreased expression of BSPRY mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | BSPRY (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | increases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of BSPRY mRNA | CTD | PMID:29391264 | entinostat | multiple interactions | ISO | BSPRY (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BSPRY mRNA | CTD | PMID:27188386 | entinostat | increases expression | ISO | BSPRY (Homo sapiens) | 6480464 | entinostat results in increased expression of BSPRY mRNA | CTD | PMID:26272509 | flavonoids | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Flavonoids results in decreased expression of BSPRY mRNA | CTD | PMID:18035473 | folic acid | multiple interactions | EXP | | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | formaldehyde | decreases expression | ISO | BSPRY (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of BSPRY mRNA | CTD | PMID:23649840 | furan | increases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | furan results in increased expression of BSPRY mRNA | CTD | PMID:25539665 and PMID:26194646 | gentamycin | increases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of BSPRY mRNA | CTD | PMID:33387578 | graphite | affects expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Graphite affects the expression of BSPRY mRNA | CTD | PMID:29933104 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BSPRY mRNA | CTD | PMID:20938992 | mercaptopurine | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Mercaptopurine results in decreased expression of BSPRY mRNA | CTD | PMID:23358152 | mercury dibromide | multiple interactions | ISO | BSPRY (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BSPRY mRNA | CTD | PMID:27188386 | methamphetamine | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Methamphetamine results in decreased expression of BSPRY mRNA | CTD | PMID:19564919 | N-nitrosodiethylamine | multiple interactions | ISO | Bspry (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BSPRY mRNA | CTD | PMID:18164116 | panobinostat | increases expression | ISO | BSPRY (Homo sapiens) | 6480464 | panobinostat results in increased expression of BSPRY mRNA | CTD | PMID:26272509 | panobinostat | multiple interactions | ISO | BSPRY (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BSPRY mRNA | CTD | PMID:27188386 | paracetamol | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of BSPRY mRNA | CTD | PMID:33387578 | paraquat | increases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Paraquat results in increased expression of BSPRY mRNA | CTD | PMID:32680482 | perfluorohexanesulfonic acid | increases expression | ISO | BSPRY (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in increased expression of BSPRY mRNA | CTD | PMID:25812627 | perfluorooctanoic acid | increases expression | ISO | BSPRY (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of BSPRY mRNA | CTD | PMID:25812627 | purine-6-thiol | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Mercaptopurine results in decreased expression of BSPRY mRNA | CTD | PMID:23358152 | rac-lactic acid | decreases expression | ISO | BSPRY (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of BSPRY mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | BSPRY (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | affects expression | ISO | BSPRY (Homo sapiens) | 6480464 | Silicon Dioxide analog affects the expression of BSPRY mRNA | CTD | PMID:23806026 | sodium arsenite | increases expression | ISO | BSPRY (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of BSPRY mRNA | CTD | PMID:29301061 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of BSPRY mRNA | CTD | PMID:37682722 | tetrachloromethane | multiple interactions | ISO | Bspry (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of BSPRY mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of BSPRY mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of BSPRY mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of BSPRY mRNA | CTD | PMID:23409001 | toluene 2,4-diisocyanate | increases expression | EXP | | 6480464 | Toluene 2 and 4-Diisocyanate results in increased expression of BSPRY mRNA | CTD | PMID:18242016 | tributylstannane | increases expression | EXP | | 6480464 | tributyltin results in increased expression of BSPRY mRNA | CTD | PMID:31939706 | trichostatin A | increases expression | ISO | BSPRY (Homo sapiens) | 6480464 | trichostatin A results in increased expression of BSPRY mRNA | CTD | PMID:24935251 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of BSPRY mRNA | CTD | PMID:33045310 | valproic acid | increases expression | ISO | BSPRY (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of BSPRY mRNA | CTD | PMID:24383497 more ... | valproic acid | multiple interactions | ISO | BSPRY (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BSPRY mRNA | CTD | PMID:27188386 | vancomycin | decreases expression | EXP | | 6480464 | Vancomycin results in decreased expression of BSPRY mRNA | CTD | PMID:18930951 | vinclozolin | decreases expression | ISO | Bspry (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of BSPRY mRNA | CTD | PMID:23555832 | |