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Gene: Akr1c14 (aldo-keto reductase family 1, member C14) Mus musculus
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Symbol: Akr1c14
Name: aldo-keto reductase family 1, member C14
Description: Exhibits androsterone dehydrogenase activity. Predicted to be involved in glycoside metabolic process; progesterone metabolic process; and prostaglandin metabolic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8; B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; and leukemia. Orthologous to several human genes including AKR1C1 (aldo-keto reductase family 1 member C1); AKR1C2 (aldo-keto reductase family 1 member C2); and AKR1C3 (aldo-keto reductase family 1 member C3); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3-alpha-hydroxysteroid dehydrogenase; 3-alpha-hydroxysteroid dehydrogenase type 1; 9030611N15Rik; AW557061
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl134,049,011 - 4,090,688 (+)EnsemblGRCm38mm10GRCm38
GRCm38134,048,991 - 4,090,560 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37134,058,837 - 4,089,668 (+)NCBIGRCm37mm9NCBIm37
MGSCv36134,058,837 - 4,089,668 (+)NCBImm8
Celera134,043,714 - 4,066,418 (+)NCBICelera
Cytogenetic Map13A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Akr1c14
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731667
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.