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Gene: POU6F1 (POU class 6 homeobox 1) Homo sapiens
Symbol: POU6F1
Name: POU class 6 homeobox 1
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to the actin cytoskeleton and nuclear body; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; antirheumatic drug; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: brain-5; brain-specific homeobox/POU domain protein 5; brn-5; BRN5; MPOU; mPOU homeobox protein; POU domain, class 6, transcription factor 1; TCFB1
Mus musculus (house mouse) : Pou6f1 (POU domain, class 6, transcription factor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pou6f1 (POU class 6 homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pou6f1 (POU class 6 homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : POU6F1 (POU class 6 homeobox 1)
Canis lupus familiaris (dog) : POU6F1 (POU class 6 homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou6f1 (POU class 6 homeobox 1)
Sus scrofa (pig) : POU6F1 (POU class 6 homeobox 1)
Chlorocebus sabaeus (green monkey) : POU6F1 (POU class 6 homeobox 1)
Heterocephalus glaber (naked mole-rat) : Pou6f1 (POU class 6 homeobox 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1251,186,936 - 51,217,708 (-)Ensembl
GRCh381251,186,936 - 51,219,875 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371251,580,719 - 51,611,477 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361249,869,232 - 49,897,744 (-)NCBINCBI36hg18NCBI36
Build 341249,869,231 - 49,897,744NCBI
Celera1250,382,323 - 50,412,965 (-)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1248,613,565 - 48,644,376 (-)NCBIHuRef
CHM1_11251,546,938 - 51,577,697 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on POU6F1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731653
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.