Vcp (valosin containing protein) - Rat Genome Database

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Gene: Vcp (valosin containing protein) Mus musculus
Analyze
Symbol: Vcp
Name: valosin containing protein
RGD ID: 731622
MGI Page MGI
Description: Exhibits several functions, including K48-linked polyubiquitin modification-dependent protein binding activity; adenyl ribonucleotide binding activity; and ubiquitin-specific protease binding activity. Involved in several processes, including aggresome assembly; positive regulation of mitochondrial membrane potential; and proteasomal protein catabolic process. Localizes to several cellular components, including ATPase complex; VCP-NSFL1C complex; and endoplasmic reticulum membrane. Is expressed in several structures, including cerebral cortex; early embryo; gonad; gut; and triceps surae muscle. Used to study inclusion body myopathy with Paget disease of bone and frontotemporal dementia. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 2Y; Paget's disease of bone; amyotrophic lateral sclerosis type 14; inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 1; and inclusion body myositis. Orthologous to human VCP (valosin containing protein); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 1H-pyrazole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 15S Mg(2+)-ATPase p97 subunit; 3110001E05; AAA ATPase p97; CDC48; homolog of yeast cdc48; Inv protein; p9; p97; p97/; p97/VCP; TER ATPase; transitional endoplasmic reticulum ATPase; valosin-containing protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Vcp-rs  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39442,979,964 - 43,000,507 (-)NCBIGRCm39mm39
GRCm39 Ensembl442,979,963 - 43,000,507 (-)Ensembl
GRCm38442,979,964 - 43,000,507 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl442,979,963 - 43,000,507 (-)EnsemblGRCm38mm10GRCm38
MGSCv37442,992,836 - 43,013,379 (-)NCBIGRCm37mm9NCBIm37
MGSCv36443,001,064 - 43,021,534 (-)NCBImm8
Celera443,010,123 - 43,030,659 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map422.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
1H-pyrazole  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-phenylbutyric acid  (ISO)
7,12-dimethyltetraphene  (ISO)
aflatoxin B1  (ISO)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcidiol  (ISO)
ceruletide  (ISO)
chenodeoxycholic acid  (ISO)
chloropicrin  (ISO)
chloroquine  (EXP,ISO)
chromium trinitrate  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
diarsenic trioxide  (ISO)
dichlorine  (ISO)
diethylstilbestrol  (EXP)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
finasteride  (ISO)
flutamide  (ISO)
folic acid  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hyaluronic acid  (ISO)
hydrazine  (ISO)
hydrogen peroxide  (ISO)
isoflavones  (ISO)
lactacystin  (ISO)
lead(II) chloride  (ISO)
leflunomide  (ISO)
lovastatin  (EXP)
lycopene  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
naphthalene  (EXP)
nefazodone  (ISO)
ochratoxin A  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenethyl isothiocyanate  (ISO)
phenobarbital  (ISO)
piroxicam  (ISO)
potassium chromate  (EXP,ISO)
prostaglandin A1  (EXP)
quartz  (ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
sirolimus  (EXP,ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
streptozocin  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
taurine  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (EXP)
valdecoxib  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
warfarin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of cysteine-type endopeptidase activity involved in apoptotic process  (IDA)
aggresome assembly  (IGI)
ATP metabolic process  (IDA)
autophagosome maturation  (IBA,ISO)
autophagy  (ISO)
cellular response to arsenite ion  (ISO)
cellular response to DNA damage stimulus  (ISO)
cellular response to heat  (ISO)
DNA repair  (IEA)
double-strand break repair  (ISO)
endoplasmic reticulum stress-induced pre-emptive quality control  (ISO)
endoplasmic reticulum to Golgi vesicle-mediated transport  (ISO)
endosome to lysosome transport via multivesicular body sorting pathway  (ISO)
ER-associated misfolded protein catabolic process  (IBA,ISO)
ERAD pathway  (ISO)
flavin adenine dinucleotide catabolic process  (ISO)
macroautophagy  (ISO)
mitotic spindle disassembly  (IBA)
NADH metabolic process  (ISO)
negative regulation of smoothened signaling pathway  (ISO)
positive regulation of ATP biosynthetic process  (ISO)
positive regulation of canonical Wnt signaling pathway  (ISO)
positive regulation of Lys63-specific deubiquitinase activity  (ISO)
positive regulation of mitochondrial membrane potential  (IMP,ISO)
positive regulation of oxidative phosphorylation  (ISO)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process  (ISO)
positive regulation of protein catabolic process  (ISO)
positive regulation of protein K63-linked deubiquitination  (ISO)
positive regulation of protein-containing complex assembly  (ISO)
positive regulation of ubiquitin-dependent protein catabolic process  (ISO)
proteasomal protein catabolic process  (ISO)
proteasome-mediated ubiquitin-dependent protein catabolic process  (IMP,ISO)
protein ubiquitination  (ISO)
protein-DNA covalent cross-linking repair  (ISO)
regulation of aerobic respiration  (ISO)
regulation of protein localization to chromatin  (ISO)
regulation of synapse organization  (ISO)
retrograde protein transport, ER to cytosol  (IBA,IMP,ISO)
stress granule disassembly  (ISO)
translesion synthesis  (ISO)
ubiquitin-dependent ERAD pathway  (IBA,ISO)
ubiquitin-dependent protein catabolic process  (IGI)
viral genome replication  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1382975   PMID:7989749   PMID:8413590   PMID:9321476   PMID:9463375   PMID:10187799   PMID:10349636   PMID:10811609   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11163219  
PMID:11483959   PMID:11689694   PMID:11740563   PMID:11756557   PMID:12351637   PMID:12411482   PMID:12477932   PMID:12504083   PMID:12520002   PMID:12529442   PMID:12847084   PMID:12904583  
PMID:12937274   PMID:14561754   PMID:14607830   PMID:14610273   PMID:14643202   PMID:14988733   PMID:15145078   PMID:15189447   PMID:15215856   PMID:15331598   PMID:15456787   PMID:15698563  
PMID:15723043   PMID:15740751   PMID:15782199   PMID:15885483   PMID:15935055   PMID:16103111   PMID:16141072   PMID:16141073   PMID:16249333   PMID:16321991   PMID:16371511   PMID:16525503  
PMID:16635246   PMID:16709668   PMID:16713576   PMID:16810319   PMID:17000876   PMID:17202270   PMID:17239345   PMID:17329348   PMID:17491009   PMID:17496150   PMID:17634366   PMID:17785525  
PMID:18178578   PMID:18307411   PMID:18332143   PMID:18462676   PMID:18468455   PMID:18495661   PMID:18706391   PMID:18712063   PMID:18799693   PMID:19423573   PMID:19521500   PMID:19805280  
PMID:19826004   PMID:20008565   PMID:20018231   PMID:20100830   PMID:20147319   PMID:20410307   PMID:20691684   PMID:20957154   PMID:21070972   PMID:21383145   PMID:21600962   PMID:21610068  
PMID:21628571   PMID:21677750   PMID:21873635   PMID:22105171   PMID:22174917   PMID:22232657   PMID:22355145   PMID:22673621   PMID:22675116   PMID:22773186   PMID:22870330   PMID:22898872  
PMID:22922362   PMID:23018179   PMID:23029473   PMID:23055941   PMID:23091005   PMID:23169451   PMID:23250913   PMID:23401548   PMID:23444373   PMID:23498975   PMID:23652004   PMID:23719816  
PMID:23722536   PMID:23737493   PMID:23844095   PMID:24007343   PMID:24089527   PMID:24130765   PMID:24158850   PMID:24160817   PMID:24218449   PMID:24424410   PMID:24457600   PMID:24461064  
PMID:24534009   PMID:24619421   PMID:24700463   PMID:24855649   PMID:24885147   PMID:25009997   PMID:25078082   PMID:25096051   PMID:25388089   PMID:25545721   PMID:25884947   PMID:26086101  
PMID:26134519   PMID:26167872   PMID:26252542   PMID:26265139   PMID:26544960   PMID:26692333   PMID:26984393   PMID:27106764   PMID:27561680   PMID:27653958   PMID:27730320   PMID:27753622  
PMID:27768726   PMID:27913212   PMID:28190767   PMID:28351922   PMID:28378742   PMID:28425440   PMID:28799247   PMID:29676259   PMID:29719249   PMID:30100055   PMID:30126895   PMID:30196744  
PMID:30476006   PMID:30504720   PMID:30550785   PMID:30562941   PMID:30595499   PMID:30654731   PMID:30713523   PMID:30979586   PMID:31040226   PMID:31073040   PMID:31162944   PMID:31577344  
PMID:31973812   PMID:32325033   PMID:32610136   PMID:33004675  


Genomics

Comparative Map Data
Vcp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39442,979,964 - 43,000,507 (-)NCBIGRCm39mm39
GRCm39 Ensembl442,979,963 - 43,000,507 (-)Ensembl
GRCm38442,979,964 - 43,000,507 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl442,979,963 - 43,000,507 (-)EnsemblGRCm38mm10GRCm38
MGSCv37442,992,836 - 43,013,379 (-)NCBIGRCm37mm9NCBIm37
MGSCv36443,001,064 - 43,021,534 (-)NCBImm8
Celera443,010,123 - 43,030,659 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map422.95NCBI
VCP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl935,053,928 - 35,072,668 (-)EnsemblGRCh38hg38GRCh38
GRCh38935,056,064 - 35,072,625 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37935,056,061 - 35,072,622 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,046,560 - 35,062,564 (-)NCBINCBI36hg18NCBI36
Build 34935,046,560 - 35,062,564NCBI
Celera934,988,041 - 35,004,706 (-)NCBI
Cytogenetic Map9p13.3NCBI
HuRef935,011,651 - 35,028,327 (-)NCBIHuRef
CHM1_1935,055,907 - 35,072,605 (-)NCBICHM1_1
Vcp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2557,210,167 - 57,229,571 (-)NCBI
Rnor_6.0 Ensembl558,426,549 - 58,445,953 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0558,426,548 - 58,445,953 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0562,951,999 - 62,971,402 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,472,100 - 59,491,508 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1559,472,279 - 59,491,687 (-)NCBI
Celera555,799,589 - 55,818,873 (-)NCBICelera
Cytogenetic Map5q22NCBI
Vcp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554721,107,164 - 1,124,076 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554721,111,649 - 1,124,076 (+)NCBIChiLan1.0ChiLan1.0
VCP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1935,712,937 - 35,729,588 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl935,712,937 - 35,729,588 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0934,907,147 - 34,923,227 (-)NCBIMhudiblu_PPA_v0panPan3
VCP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11151,636,986 - 51,651,749 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1151,637,411 - 51,651,714 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,205,792 - 50,220,556 (-)NCBI
ROS_Cfam_1.01152,702,444 - 52,717,215 (-)NCBI
UMICH_Zoey_3.11151,246,536 - 51,261,297 (-)NCBI
UNSW_CanFamBas_1.01151,231,677 - 51,246,443 (-)NCBI
UU_Cfam_GSD_1.01151,933,494 - 51,948,301 (-)NCBI
LOC101972576
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947166,538,385 - 166,554,770 (-)NCBI
SpeTri2.0NW_0049365243,085,959 - 3,102,461 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VCP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1235,796,446 - 235,876,321 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11235,854,532 - 235,869,712 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21263,379,929 - 263,394,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103219235
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11245,545,139 - 45,560,702 (+)NCBI
ChlSab1.1 Ensembl1245,545,507 - 45,563,380 (+)Ensembl
Vero_WHO_p1.0NW_02366603842,661,397 - 42,677,470 (+)NCBI
Vcp
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624915253,240 - 270,440 (-)NCBI

Position Markers
RH125945  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38442,992,567 - 42,992,803UniSTSGRCm38
MGSCv37443,005,439 - 43,005,675UniSTSGRCm37
Celera443,022,717 - 43,022,953UniSTS
Cytogenetic Map4A5UniSTS
cM Map423.0UniSTS
Vcp-rs  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X104,347,885 - 104,348,229UniSTSGRCm38
MGSCv37X101,543,224 - 101,543,568UniSTSGRCm37
CeleraX91,239,695 - 91,240,039UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic MapXC-DUniSTS
cM MapX45.5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763365441Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117215009Mouse
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261689063979Mouse
1357645Lvrq9_mliver weight QTL 9 (mouse)Not determined41789261689063979Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261689063979Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261689063979Mouse
25440481Moaq1_mmodifier of alien QTL 1 (mouse)41950000046000000Mouse
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1302184Aaom1_mautoimmune aoritis in MRL mice 1 (mouse)Not determined42432229946332776Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
4142290Ssrq9_mstress response QTL 9 (mouse)Not determined3439516046332776Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000129100000Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
10412178Habiir2_mhyperoxic acute lung injury imprinted region 2 (mouse)Not determined43945212663365441Mouse
1301786Bpq3_mblood pressure QTL 3 (mouse)Not determined44240224076402381Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108500000Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir129-1mmu-miR-129-5pOncomiRDBexternal_infoNANA22536440
Mir129-2mmu-miR-129-5pOncomiRDBexternal_infoNANA22536440

Predicted Target Of
Summary Value
Count of predictions:738
Count of miRNA genes:474
Interacting mature miRNAs:553
Transcripts:ENSMUST00000030164, ENSMUST00000139843, ENSMUST00000148182, ENSMUST00000154423, ENSMUST00000154541
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC005259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF122047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL672276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY732145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ871268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z14044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000030164   ⟹   ENSMUSP00000030164
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl442,979,963 - 43,000,507 (-)Ensembl
RefSeq Acc Id: ENSMUST00000139843
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl442,992,735 - 42,993,758 (-)Ensembl
RefSeq Acc Id: ENSMUST00000148182
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl442,993,712 - 43,000,433 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154423
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl442,986,242 - 42,989,330 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154541
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl442,984,366 - 42,985,821 (-)Ensembl
RefSeq Acc Id: NM_009503   ⟹   NP_033529
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39442,979,964 - 43,000,507 (-)NCBI
GRCm38442,979,964 - 43,000,507 (-)ENTREZGENE
MGSCv37442,992,836 - 43,013,379 (-)RGD
Celera443,010,123 - 43,030,659 (-)RGD
cM Map4 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033529   ⟸   NM_009503
- UniProtKB: Q01853 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000030164   ⟸   ENSMUST00000030164
Protein Domains
AAA   CDC48_2

Promoters
RGD ID:6836648
Promoter ID:MM_KWN:37298
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   MEF_B6
Transcripts:OTTMUST00000015333
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36442,998,766 - 42,999,266 (-)MPROMDB
RGD ID:6883178
Promoter ID:EPDNEW_M5040
Type:initiation region
Name:Vcp_1
Description:Mus musculus valosin containing protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38443,000,434 - 43,000,494EPDNEW
RGD ID:6836649
Promoter ID:MM_KWN:37299
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung,   MEF_B6
Transcripts:OTTMUST00000015334
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36443,001,716 - 43,002,567 (-)MPROMDB
RGD ID:6836646
Promoter ID:MM_KWN:37300
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   MEF_B6
Transcripts:OTTMUST00000015332
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36443,006,666 - 43,007,177 (-)MPROMDB
RGD ID:6836645
Promoter ID:MM_KWN:37301
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000015330,   OTTMUST00000015331
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36443,013,016 - 43,013,782 (-)MPROMDB
RGD ID:6849558
Promoter ID:EP59010
Type:single initiation site
Name:MM_TERA
Description:p97 transitional endoplasmic reticulum (TER) ATPasevalosin-containing protein, VCP gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Tissues & Cell Lines:housekeeping gene
Experiment Methods:Primer extension with homologous sequence ladder
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv37443,013,305 - 43,013,365EPD
MGSCv36443,013,305 - 43,013,365EPD

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99919 AgrOrtholog
Ensembl Genes ENSMUSG00000028452 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000030164 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000030164 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_ATPase_CDC48 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Asp_de-COase-like_dom_sf UniProtKB/Swiss-Prot
  ATPase_AAA_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cdc48_dom2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CDC48_domain_2-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CDC4_N-term_subdom UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vps4_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:269523 UniProtKB/Swiss-Prot
MGD MGI:99919 ENTREZGENE
NCBI Gene 269523 ENTREZGENE
Pfam AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CDC48_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CDC48_N UniProtKB/Swiss-Prot
  Vps4_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Vcp PhenoGen
PROSITE AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CDC48_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CDC48_N UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50692 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54585 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs CDC48 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q01853 ENTREZGENE
  Q8BNF8_MOUSE UniProtKB/TrEMBL
  TERA_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3TFH9 UniProtKB/Swiss-Prot
  Q3TIM2 UniProtKB/Swiss-Prot
  Q3TXN9 UniProtKB/Swiss-Prot
  Q6PI18 UniProtKB/Swiss-Prot
  Q8BSR6 UniProtKB/Swiss-Prot
  Q8CEG4 UniProtKB/Swiss-Prot