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Gene: GRIK1 (glutamate ionotropic receptor kainate type subunit 1) Homo sapiens
Symbol: GRIK1
Name: glutamate ionotropic receptor kainate type subunit 1
RGD ID: 731546
Description: Exhibits kainate selective glutamate receptor activity. Predicted to be involved in several processes, including chemical synaptic transmission; modulation of chemical synaptic transmission; and positive regulation of gamma-aminobutyric acid secretion. Predicted to localize to several cellular components, including glutamatergic synapse; kainate selective glutamate receptor complex; and synaptic membrane. Implicated in childhood absence epilepsy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EAA3; EEA3; excitatory amino acid receptor 3; GLR5; GluK1; gluR-5; GLUR5; glutamate receptor 5; glutamate receptor ionotropic, kainate 1; glutamate receptor, ionotropic kainate 1; glutamate receptor, ionotropic, kainate 1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2129,536,933 - 29,940,033 (-)EnsemblGRCh38hg38GRCh38
GRCh382129,536,933 - 29,939,996 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372130,909,254 - 31,312,282 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362129,831,125 - 30,234,153 (-)NCBINCBI36hg18NCBI36
Build 342129,831,126 - 30,234,153NCBI
Celera2116,092,373 - 16,495,412 (-)NCBI
Cytogenetic Map21q21.3NCBI
HuRef2116,317,387 - 16,721,110 (-)NCBIHuRef
CHM1_12130,470,770 - 30,873,897 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GRIK1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731546
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.