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Gene: MTA1 (metastasis associated 1) Homo sapiens
Symbol: MTA1
Name: metastasis associated 1
Description: Exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; RNA polymerase II repressing transcription factor binding activity; and transcription coregulator activity. Involved in several processes, including positive regulation of protein autoubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process; and response to ionizing radiation. Localizes to cytosol; microtubule; and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: metastasis associated gene 1 protein; metastasis associated protein; metastasis-associated protein MTA1
Mus musculus (house mouse) : Mta1 (metastasis associated 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mta1 (metastasis associated 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mta1 (metastasis associated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MTA1 (metastasis associated 1)
Canis lupus familiaris (dog) : MTA1 (metastasis associated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mta1 (metastasis associated 1)
Sus scrofa (pig) : MTA1 (metastasis associated 1)
Chlorocebus sabaeus (African green monkey) : MTA1 (metastasis associated 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl14105,419,820 - 105,470,729 (+)EnsemblGRCh38hg38GRCh38
GRCh3814105,419,827 - 105,470,729 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714105,886,186 - 105,937,066 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614104,957,231 - 105,008,107 (+)NCBINCBI36hg18NCBI36
Build 3414104,957,410 - 105,008,100NCBI
Celera1485,954,132 - 85,985,842 (+)NCBI
Cytogenetic Map14q32.33NCBI
HuRef1486,101,203 - 86,132,910 (+)NCBIHuRef
CHM1_114105,823,945 - 105,873,924 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MTA1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731516
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.