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Gene: Sh3bp4 (SH3-domain binding protein 4) Mus musculus
Symbol: Sh3bp4
Name: SH3-domain binding protein 4
Description: Predicted to have GDP-dissociation inhibitor activity; Ras GTPase binding activity; and identical protein binding activity. Predicted to be involved in several processes, including negative regulation of GTPase activity; negative regulation of TOR signaling; and protein localization to lysosome. Predicted to localize to the cytoplasm. Is expressed in cerebral cortex marginal layer and olfactory cortex marginal layer. Orthologous to human SH3BP4 (SH3 domain binding protein 4); INTERACTS WITH 4,4'-diaminodiphenylmethane; 4-hydroxyphenyl retinamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI594717; AW227605; BOG25; SH3 domain-binding protein 4
Homo sapiens (human) : SH3BP4 (SH3 domain binding protein 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sh3bp4 (SH3-domain binding protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sh3bp4 (SH3 domain binding protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SH3BP4 (SH3 domain binding protein 4)
Canis lupus familiaris (dog) : SH3BP4 (SH3 domain binding protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sh3bp4 (SH3 domain binding protein 4)
Sus scrofa (pig) : SH3BP4 (SH3 domain binding protein 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl189,070,415 - 89,155,068 (+)Ensembl
GRCm38189,070,333 - 89,155,087 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37190,967,037 - 91,050,368 (+)NCBIGRCm37mm9NCBIm37
MGSCv36190,901,633 - 90,984,964 (+)NCBImm8
Celera192,032,349 - 92,112,519 (+)NCBICelera
Cytogenetic Map1 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sh3bp4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731486
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.