Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: NEUROD1 (neuronal differentiation 1) Homo sapiens
Analyze
Symbol: NEUROD1
Name: neuronal differentiation 1
Description: Exhibits several functions, including E-box binding activity; RNA polymerase II activating transcription factor binding activity; and protein heterodimerization activity. Contributes to sequence-specific DNA binding activity. Involved in several processes, including insulin secretion; nitric oxide mediated signal transduction; and regulation of transcription, DNA-templated. Localizes to the RNA polymerase II transcription factor complex. Implicated in glucose intolerance; hyperglycemia; maturity-onset diabetes of the young type 6; type 1 diabetes mellitus; and type 2 diabetes mellitus. Biomarker of obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: basic helix-loop-helix transcription factor; beta-cell E-box transactivator 2; BETA2; BHF-1; bHLHa3; class A basic helix-loop-helix protein 3; MODY6; NEUROD; neurogenic differentiation 1; neurogenic differentiation factor 1; neurogenic helix-loop-helix protein NEUROD
Orthologs:
Mus musculus (house mouse) : Neurod1 (neurogenic differentiation 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Neurod1 (neuronal differentiation 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Neurod1 (neuronal differentiation 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NEUROD1 (neuronal differentiation 1)
Canis lupus familiaris (dog) : NEUROD1 (neuronal differentiation 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Neurod1 (neuronal differentiation 1)
Sus scrofa (pig) : NEUROD1 (neuronal differentiation 1)
Chlorocebus sabaeus (African green monkey) : NEUROD1 (neuronal differentiation 1)
Heterocephalus glaber (naked mole-rat) : Neurod1 (neuronal differentiation 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2181,673,088 - 181,680,876 (-)Ensembl
GRCh382181,668,295 - 181,680,665 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372182,540,833 - 182,545,392 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362182,249,439 - 182,253,626 (-)NCBINCBI36hg18NCBI36
Build 342182,366,700 - 182,370,760NCBI
Celera2176,137,248 - 176,141,434 (-)NCBI
Cytogenetic Map2q31.3NCBI
HuRef2174,397,426 - 174,401,985 (-)NCBIHuRef
CHM1_12182,546,618 - 182,551,246 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NEUROD1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731467
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-01-28
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.