Itfg1 (integrin alpha FG-GAP repeat containing 1) - Rat Genome Database
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Gene: Itfg1 (integrin alpha FG-GAP repeat containing 1) Mus musculus
Analyze
Symbol: Itfg1
Name: integrin alpha FG-GAP repeat containing 1
RGD ID: 731464
MGI Page MGI
Description: Predicted to localize to plasma membrane. Is expressed in extraembryonic component; nervous system; and neural retina. Orthologous to human ITFG1 (integrin alpha FG-GAP repeat containing 1); INTERACTS WITH 1,2-dimethylhydrazine; 4-hydroxyphenyl retinamide; Aroclor 1254.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310047C21Rik; AI314457; Cda08; D8Wsu49; D8Wsu49e; integrin-alpha FG-GAP repeat-containing protein 1; linkin; T-cell immunomodulatory protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39886,444,186 - 86,567,578 (-)NCBIGRCm39mm39
GRCm38885,717,557 - 85,840,949 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,717,578 - 85,840,921 (-)EnsemblGRCm38mm10GRCm38
MGSCv37888,241,456 - 88,364,848 (-)NCBIGRCm37mm9NCBIm37
MGSCv36888,608,645 - 88,730,877 (-)NCBImm8
Celera890,013,580 - 90,138,207 (-)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.61NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:9811942   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11591653   PMID:12466851   PMID:12477932   PMID:12520002  
PMID:12598909   PMID:12904583   PMID:14610273   PMID:15489334   PMID:15747579   PMID:15782199   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Itfg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39886,444,186 - 86,567,578 (-)NCBIGRCm39mm39
GRCm38885,717,557 - 85,840,949 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,717,578 - 85,840,921 (-)EnsemblGRCm38mm10GRCm38
MGSCv37888,241,456 - 88,364,848 (-)NCBIGRCm37mm9NCBIm37
MGSCv36888,608,645 - 88,730,877 (-)NCBImm8
Celera890,013,580 - 90,138,207 (-)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.61NCBI
ITFG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1647,154,387 - 47,464,149 (-)EnsemblGRCh38hg38GRCh38
GRCh381647,154,391 - 47,461,246 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371647,188,302 - 47,495,018 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361645,746,798 - 46,052,519 (-)NCBINCBI36hg18NCBI36
Build 341645,746,800 - 46,052,516NCBI
Celera1631,697,397 - 32,002,959 (-)NCBI
Cytogenetic Map16q12.1NCBI
HuRef1633,078,995 - 33,385,580 (-)NCBIHuRef
CHM1_11648,595,277 - 48,902,215 (-)NCBICHM1_1
Itfg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01922,281,906 - 22,403,548 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1922,281,906 - 22,403,542 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01933,289,326 - 33,410,847 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41922,561,637 - 22,682,885 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11922,547,513 - 22,687,705 (+)NCBI
Celera1921,075,489 - 21,195,835 (+)NCBICelera
Cytogenetic Map19p11NCBI
Itfg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554747,801,203 - 8,020,961 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554747,800,984 - 8,020,891 (+)NCBIChiLan1.0ChiLan1.0
ITFG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11646,305,573 - 46,611,710 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1646,305,573 - 46,613,463 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01627,416,955 - 27,720,197 (-)NCBIMhudiblu_PPA_v0panPan3
ITFG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl267,476,650 - 67,766,475 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1267,475,847 - 67,767,674 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Itfg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936475518,262 - 779,215 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITFG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl637,193,711 - 37,432,884 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1637,193,632 - 37,430,910 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2632,411,274 - 32,673,834 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITFG1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1533,003,454 - 33,288,295 (-)NCBI
ChlSab1.1 Ensembl533,002,463 - 33,288,338 (-)Ensembl
Itfg1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624914721,206 - 1,013,734 (-)NCBI

Position Markers
AW554709  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38885,718,092 - 85,718,182UniSTSGRCm38
MGSCv37888,241,991 - 88,242,081UniSTSGRCm37
Celera890,014,115 - 90,014,205UniSTS
Cytogenetic Map8C4UniSTS
cM Map839.0UniSTS
Whitehead/MRC_RH81018.61UniSTS
MHAa7b7.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38885,745,378 - 85,745,576UniSTSGRCm38
MGSCv37888,269,277 - 88,269,475UniSTSGRCm37
Celera890,041,903 - 90,042,101UniSTS
Cytogenetic Map8C4UniSTS
cM Map839.0UniSTS
Whitehead_YAC8 UniSTS
AI314457  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38885,717,650 - 85,717,883UniSTSGRCm38
MGSCv37888,241,549 - 88,241,782UniSTSGRCm37
Celera890,013,673 - 90,013,906UniSTS
Cytogenetic Map8C4UniSTS
cM Map839.0UniSTS
Whitehead/MRC_RH81016.16UniSTS
RH124864  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38885,717,712 - 85,717,919UniSTSGRCm38
MGSCv37888,241,611 - 88,241,818UniSTSGRCm37
Celera890,013,735 - 90,013,942UniSTS
Cytogenetic Map8C4UniSTS
cM Map839.0UniSTS
MARC_13783-13784:1006796492:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38885,725,550 - 85,726,237UniSTSGRCm38
MGSCv37888,249,449 - 88,250,136UniSTSGRCm37
Celera890,022,093 - 90,022,780UniSTS
Cytogenetic Map8C4UniSTS
cM Map839.0UniSTS
RH125849  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38885,717,710 - 85,717,922UniSTSGRCm38
MGSCv37888,241,609 - 88,241,821UniSTSGRCm37
Celera890,013,733 - 90,013,945UniSTS
Cytogenetic Map8C4UniSTS
cM Map839.0UniSTS
Whitehead/MRC_RHX1599.69UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873202495107202598Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined875675517109675623Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined875685348109685497Mouse
1301808Nhdlq1_mnon-HDL QTL 1 (mouse)Not determined875685348109685497Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined875685348109685497Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined875685348109685497Mouse
1301099Cbm2_mcerebellum weight 2 (mouse)Not determined878518613112518703Mouse
1301581Char2_mP. chabaudi malaria resistance QTL 2 (mouse)Not determined879082178113082403Mouse
12904012Cfq10_mconditioned fear QTL 10 (mouse)88006677589014359Mouse
10755530Wbc2_mwhite blood cell count 2 (mouse)881092664115092664Mouse
10755519Wbc1_mwhite blood cell count 1 (mouse)881619151115619151Mouse
1301766Desp1_mdespair 1 (mouse)Not determined884759576118759741Mouse
1302049Heal1_mwound healing/regeneration 1 (mouse)Not determined885716921119717069Mouse
1301253Skmw2_mskeletal muscle weight 2 (mouse)Not determined885716921119717069Mouse
10045619Heal14_mwound healing/regeneration 14 (mouse)Not determined885716921119717069Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:405
Count of miRNA genes:277
Interacting mature miRNAs:331
Transcripts:ENSMUST00000034140
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_028007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC117185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC158357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV257002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP765330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN175510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000034140   ⟹   ENSMUSP00000034140
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,717,578 - 85,840,921 (-)Ensembl
RefSeq Acc Id: ENSMUST00000210133
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,738,787 - 85,741,527 (-)Ensembl
RefSeq Acc Id: ENSMUST00000210572
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,731,244 - 85,742,518 (-)Ensembl
RefSeq Acc Id: ENSMUST00000210604
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl885,723,905 - 85,727,710 (-)Ensembl
RefSeq Acc Id: NM_028007   ⟹   NP_082283
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39886,444,186 - 86,567,578 (-)NCBI
GRCm38885,717,557 - 85,840,949 (-)ENTREZGENE
MGSCv37888,241,456 - 88,364,848 (-)RGD
Celera890,013,580 - 90,138,207 (-)RGD
cM Map8 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_082283 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH03977 (Get FASTA)   NCBI Sequence Viewer  
  BAB26552 (Get FASTA)   NCBI Sequence Viewer  
  EDL11022 (Get FASTA)   NCBI Sequence Viewer  
  Q99KW9 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_082283   ⟸   NM_028007
- Peptide Label: precursor
- UniProtKB: Q99KW9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000034140   ⟸   ENSMUST00000034140

Promoters
RGD ID:8667773
Promoter ID:EPDNEW_M11918
Type:multiple initiation site
Name:Itfg1_2
Description:Mus musculus integrin alpha FG-GAP repeat containing 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11919  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38885,840,761 - 85,840,821EPDNEW
RGD ID:8667775
Promoter ID:EPDNEW_M11919
Type:initiation region
Name:Itfg1_1
Description:Mus musculus integrin alpha FG-GAP repeat containing 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11918  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38885,840,921 - 85,840,981EPDNEW
RGD ID:6843344
Promoter ID:MM_KWN:55161
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000061385,   NM_028007,   OTTMUST00000077272,   OTTMUST00000077274,   OTTMUST00000077277,   OTTMUST00000081079,   UC009MQI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36888,363,956 - 88,365,382 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:106419 AgrOrtholog
Ensembl Genes ENSMUSG00000031703 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000034140 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000034140 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro FG-GAP UniProtKB/Swiss-Prot
  Tip UniProtKB/Swiss-Prot
KEGG Report mmu:71927 UniProtKB/Swiss-Prot
MGD MGI:106419 ENTREZGENE
NCBI Gene 71927 ENTREZGENE
PANTHER PTHR13412 UniProtKB/Swiss-Prot
Pfam VCBS UniProtKB/Swiss-Prot
PhenoGen Itfg1 PhenoGen
UniGene Mm.61018 ENTREZGENE
UniProt Q99KW9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary E9QQ11 UniProtKB/Swiss-Prot
  Q9D6X1 UniProtKB/Swiss-Prot