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Gene: Myo5a (myosin VA) Mus musculus
Symbol: Myo5a
Name: myosin VA
Description: Exhibits several functions, including Rab GTPase binding activity; calmodulin binding activity; and disordered domain specific binding activity. Involved in several processes, including anagen; establishment of endoplasmic reticulum localization to postsynapse; and secretion by cell. Localizes to several cellular components, including cytoplasmic vesicle; cytoskeleton; and glutamatergic synapse. Colocalizes with microtubule plus-end. Is expressed in central nervous system; peripheral nervous system ganglion; and retina. Used to study Griscelli syndrome type 1. Human ortholog(s) of this gene implicated in Griscelli syndrome type 1. Orthologous to human MYO5A (myosin VA); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9630007J19Rik; AI413174; AI661011; d; d-120J; Dbv; dilute lethal-20J protein; dilute myosin heavy chain, non-muscle; flail; flailer; flr; MVa; Myo5; myosin-Va; MyoVA; Sev-1; unconventional myosin-Va
Homo sapiens (human) : MYO5A (myosin VA)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myo5a (myosin VA)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myo5a (myosin VA)
Pan paniscus (bonobo/pygmy chimpanzee) : MYO5A (myosin VA)
Canis lupus familiaris (dog) : MYO5A (myosin VA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myo5a (myosin VA)
Sus scrofa (pig) : MYO5A (myosin VA)
Chlorocebus sabaeus (African green monkey) : MYO5A (myosin VA)
Heterocephalus glaber (naked mole-rat) : Myo5a (myosin VA)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl975,071,015 - 75,223,688 (+)EnsemblGRCm38mm10GRCm38
GRCm38975,069,799 - 75,223,688 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37974,919,013 - 75,071,495 (+)NCBIGRCm37mm9NCBIm37
MGSCv36974,858,205 - 75,005,381 (+)NCBImm8
Celera972,225,104 - 72,382,491 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map942.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Myo5a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731454
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.