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Gene: AKAP8 (A-kinase anchoring protein 8) Homo sapiens
Symbol: AKAP8
Name: A-kinase anchoring protein 8
RGD ID: 731444
Description: Exhibits histone deacetylase binding activity and protein kinase A regulatory subunit binding activity. Involved in cell cycle G2/M phase transition; positive regulation of histone deacetylation; and regulation of histone phosphorylation. Localizes to nucleolus and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A kinase (PRKA) anchor protein 8; A-kinase anchor protein 8; A-kinase anchor protein 95 kDa; A-kinase anchor protein, 95kDa; AKAP 95; AKAP-8; AKAP-95; AKAP95; DKFZp586B1222
Mus musculus (house mouse) : Akap8 (A kinase (PRKA) anchor protein 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Akap8 (A-kinase anchoring protein 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akap8 (A-kinase anchoring protein 8)
Pan paniscus (bonobo/pygmy chimpanzee) : AKAP8 (A-kinase anchoring protein 8)
Canis lupus familiaris (dog) : AKAP8 (A-kinase anchoring protein 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akap8 (A-kinase anchoring protein 8)
Sus scrofa (pig) : AKAP8 (A-kinase anchoring protein 8)
Chlorocebus sabaeus (African green monkey) : AKAP8 (A-kinase anchoring protein 8)
Heterocephalus glaber (naked mole-rat) : Akap8 (A-kinase anchoring protein 8)
more info ...
Related Pseudogenes: AKAP8P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1915,353,385 - 15,379,798 (-)EnsemblGRCh38hg38GRCh38
GRCh381915,353,385 - 15,379,787 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371915,464,332 - 15,490,638 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361915,325,335 - 15,351,603 (-)NCBINCBI36hg18NCBI36
Build 341915,325,335 - 15,351,603NCBI
Celera1915,359,984 - 15,386,240 (-)NCBI
Cytogenetic Map19p13.12NCBI
HuRef1915,032,304 - 15,058,582 (-)NCBIHuRef
CHM1_11915,463,860 - 15,490,252 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on AKAP8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731444
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.