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Gene: Doc2a (double C2, alpha) Mus musculus
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Symbol: Doc2a
Name: double C2, alpha
RGD ID: 731424
Description: Predicted to have calcium ion binding activity and calcium-dependent phospholipid binding activity. Involved in regulation of calcium ion-dependent exocytosis and spontaneous neurotransmitter secretion. Predicted to localize to extrinsic component of synaptic vesicle membrane; lysosome; and nuclear lumen. Is expressed in cerebral cortex. Orthologous to human DOC2A (double C2 domain alpha); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: doc2-alpha; double C2-like domain-containing protein alpha
Orthologs:
Homo sapiens (human) : DOC2A (double C2 domain alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Doc2a (double C2 domain alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Doc2a (double C2 domain alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : DOC2A (double C2 domain alpha)
Canis lupus familiaris (dog) : DOC2A (double C2 domain alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Doc2a (double C2 domain alpha)
Sus scrofa (pig) : DOC2A (double C2 domain alpha)
Chlorocebus sabaeus (African green monkey) : DOC2A (double C2 domain alpha)
Heterocephalus glaber (naked mole-rat) : Doc2a (double C2 domain alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,446,525 - 126,451,877 (+)NCBI
GRCm387126,846,983 - 126,852,705 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,847,416 - 126,852,705 (+)EnsemblGRCm38mm10GRCm38
MGSCv377133,991,067 - 133,996,219 (+)NCBIGRCm37mm9NCBIm37
MGSCv367126,638,701 - 126,643,853 (+)NCBImm8
Celera7126,695,691 - 126,700,843 (+)NCBICelera
Cytogenetic Map7F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Doc2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731424
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.