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Gene: Doc2a (double C2, alpha) Mus musculus
Symbol: Doc2a
Name: double C2, alpha
RGD ID: 731424
Description: Predicted to have calcium ion binding activity and calcium-dependent phospholipid binding activity. Involved in regulation of calcium ion-dependent exocytosis and spontaneous neurotransmitter secretion. Predicted to localize to extrinsic component of synaptic vesicle membrane; lysosome; and nuclear lumen. Is expressed in cerebral cortex. Orthologous to human DOC2A (double C2 domain alpha); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: doc2-alpha; double C2-like domain-containing protein alpha
Homo sapiens (human) : DOC2A (double C2 domain alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Doc2a (double C2 domain alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Doc2a (double C2 domain alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : DOC2A (double C2 domain alpha)
Canis lupus familiaris (dog) : DOC2A (double C2 domain alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Doc2a (double C2 domain alpha)
Sus scrofa (pig) : DOC2A (double C2 domain alpha)
Chlorocebus sabaeus (African green monkey) : DOC2A (double C2 domain alpha)
Heterocephalus glaber (naked mole-rat) : Doc2a (double C2 domain alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm397126,446,525 - 126,451,877 (+)NCBI
GRCm387126,846,983 - 126,852,705 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,847,416 - 126,852,705 (+)EnsemblGRCm38mm10GRCm38
MGSCv377133,991,067 - 133,996,219 (+)NCBIGRCm37mm9NCBIm37
MGSCv367126,638,701 - 126,643,853 (+)NCBImm8
Celera7126,695,691 - 126,700,843 (+)NCBICelera
Cytogenetic Map7F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Doc2a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731424
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.