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Gene: Klhl12 (kelch-like 12) Mus musculus
Symbol: Klhl12
Name: kelch-like 12
Description: Predicted to have identical protein binding activity. Predicted to be involved in several processes, including COPII vesicle coating; mesenchymal cell differentiation; and protein monoubiquitination. Predicted to localize to several cellular components, including COPII vesicle coat; Cul3-RING ubiquitin ligase complex; and centriolar satellite. Is expressed in genitourinary system. Orthologous to human KLHL12 (kelch like family member 12); PARTICIPATES IN Wnt signaling, canonical pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; choline; folic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C3ip1; CUL3-interacting protein 1; kelch-like protein 12; kelch-like protein C3IP1; MGC7076
Homo sapiens (human) : KLHL12 (kelch like family member 12)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Klhl12 (kelch-like family member 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klhl12 (kelch like family member 12)
Pan paniscus (bonobo/pygmy chimpanzee) : KLHL12 (kelch like family member 12)
Canis lupus familiaris (dog) : KLHL12 (kelch like family member 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klhl12 (kelch like family member 12)
Sus scrofa (pig) : KLHL12 (kelch like family member 12)
Chlorocebus sabaeus (African green monkey) : KLHL12 (kelch like family member 12)
Heterocephalus glaber (naked mole-rat) : Klhl12 (kelch like family member 12)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1134,455,531 - 134,491,018 (+)EnsemblGRCm38mm10GRCm38
GRCm381134,455,495 - 134,490,880 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371136,352,132 - 136,387,450 (+)NCBIGRCm37mm9NCBIm37
MGSCv361136,271,966 - 136,307,284 (+)NCBImm8
Celera1137,062,147 - 137,097,576 (+)NCBICelera
Cytogenetic Map1E4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Klhl12
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731419
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.