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Gene: GLRB (glycine receptor beta) Homo sapiens
Symbol: GLRB
Name: glycine receptor beta
Description: Exhibits extracellularly glycine-gated ion channel activity. Contributes to extracellularly glycine-gated chloride channel activity and glycine binding activity. Involved in several processes, including chloride transmembrane transport; neuropeptide signaling pathway; and startle response. Localizes to glycine-gated chloride channel complex. Implicated in hyperekplexia 2.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glycine receptor 58 kDa subunit; glycine receptor subunit beta; glycine receptor, beta subunit; HKPX2
Mus musculus (house mouse) : Glrb (glycine receptor, beta subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : Glrb (glycine receptor, beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glrb (glycine receptor beta)
Pan paniscus (bonobo/pygmy chimpanzee) : GLRB (glycine receptor beta)
Canis lupus familiaris (dog) : GLRB (glycine receptor beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glrb (glycine receptor beta)
Sus scrofa (pig) : GLRB (glycine receptor beta)
Chlorocebus sabaeus (African green monkey) : GLRB (glycine receptor beta)
Heterocephalus glaber (naked mole-rat) : Glrb (glycine receptor beta)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl4157,076,125 - 157,172,090 (+)EnsemblGRCh38hg38GRCh38
GRCh384157,076,125 - 157,172,090 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374157,997,277 - 158,093,251 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364158,216,788 - 158,312,304 (+)NCBINCBI36hg18NCBI36
Build 344158,354,942 - 158,450,454NCBI
Celera4155,340,138 - 155,436,102 (+)NCBI
Cytogenetic Map4q32.1NCBI
HuRef4153,748,311 - 153,844,227 (+)NCBIHuRef
CHM1_14157,974,414 - 158,070,403 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GLRB
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731361
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.