Gene: ASIC1 (acid sensing ion channel subunit 1) Homo sapiens
Symbol: ASIC1
Name: acid sensing ion channel subunit 1
Description: This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACCN2; ACCN2 variant 3; acid sensing (proton gated) ion channel 1; acid sensing ion channel 1; acid-sensing (proton-gated) ion channel 1; acid-sensing ion channel 1; acid-sensing ion channel 1a protein; amiloride-sensitive cation channel 2, neuronal; ASIC; ASIC1A; BNaC2; brain sodium channel 2; Cation channel, amiloride-sensitive, neuronal, 2; hBNaC2
Mus musculus (house mouse) : Asic1 (acid-sensing (proton-gated) ion channel 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Asic1 (acid sensing ion channel subunit 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Asic1 (acid sensing ion channel subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ASIC1 (acid sensing ion channel subunit 1)
Canis lupus familiaris (dog) : ASIC1 (acid sensing ion channel subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Asic1 (acid sensing ion channel subunit 1)
Sus scrofa (pig) : ASIC1 (acid sensing ion channel subunit 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381250,057,637 - 50,083,622 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371250,451,420 - 50,477,405 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,737,754 - 48,763,661 (+)NCBINCBI36hg18NCBI36
Build 341248,737,753 - 48,763,660NCBI
Celera1249,246,955 - 49,272,856 (+)NCBI
Cytogenetic Map12q13.12NCBI
HuRef1247,485,455 - 47,510,311 (+)NCBIHuRef
CHM1_11250,417,567 - 50,443,552 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ASIC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731360
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-04-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.