Syt2 (synaptotagmin II) - Rat Genome Database

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Gene: Syt2 (synaptotagmin II) Mus musculus
Analyze
Symbol: Syt2
Name: synaptotagmin II
RGD ID: 731270
MGI Page MGI
Description: Enables ion binding activity and phospholipid binding activity. Involved in calcium-dependent activation of synaptic vesicle fusion. Located in axon and plasma membrane. Is active in neuromuscular junction. Is expressed in several structures, including central nervous system; heart; integumental system; peripheral nervous system; and sensory organ. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome and congenital myasthenic syndrome 7. Orthologous to human SYT2 (synaptotagmin 2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: IP4BP; KIAA4194; mKIAA4194; R74640; synaptotagmin 2; synaptotagmin-2; sytII
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,574,319 - 134,680,887 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1134,574,415 - 134,690,331 (+)EnsemblGRCm39 Ensembl
GRCm381134,646,534 - 134,753,149 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,646,677 - 134,762,593 (+)EnsemblGRCm38mm10GRCm38
MGSCv371136,543,258 - 136,645,994 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361136,463,092 - 136,565,828 (+)NCBIMGSCv36mm8
Celera1137,257,554 - 137,373,520 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Synaptotagmin-2, and -1, linked to neurotransmission impairment and vulnerability in Spinal Muscular Atrophy. Tejero R, etal., Hum Mol Genet. 2016 Aug 29. pii: ddw297.
Additional References at PubMed
PMID:1495973   PMID:2132728   PMID:7749232   PMID:7961887   PMID:8058779   PMID:8626542   PMID:8653788   PMID:8747928   PMID:8889548   PMID:9914469   PMID:10349636   PMID:10753658  
PMID:11042159   PMID:11076861   PMID:11217851   PMID:11543631   PMID:12477932   PMID:12546816   PMID:12860971   PMID:14504267   PMID:14610273   PMID:14681479   PMID:14715936   PMID:15123599  
PMID:15350218   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16407561   PMID:16407767   PMID:16512683   PMID:16602821   PMID:16642042   PMID:17124501   PMID:17167418   PMID:17185412  
PMID:17192432   PMID:17492637   PMID:17500595   PMID:18046404   PMID:18158333   PMID:18434415   PMID:18614564   PMID:19208631   PMID:19234194   PMID:19279571   PMID:19345204   PMID:19473977  
PMID:19633667   PMID:19945391   PMID:20473299   PMID:20926654   PMID:21267068   PMID:21338883   PMID:21441923   PMID:21677750   PMID:21835343   PMID:21873635   PMID:22454523   PMID:22537499  
PMID:22539967   PMID:22794259   PMID:23172916   PMID:23359859   PMID:23648184   PMID:23790753   PMID:23807078   PMID:23986861   PMID:24154525   PMID:24427314   PMID:25232102   PMID:25757744  
PMID:26134646   PMID:26287463   PMID:27052163   PMID:27154627   PMID:27210552   PMID:27325702   PMID:27399837   PMID:28099850   PMID:28363983   PMID:28521135   PMID:29024662   PMID:29184203  
PMID:29518331   PMID:29611808   PMID:30318414   PMID:30667565   PMID:30870432   PMID:31160536   PMID:31221192   PMID:31235642   PMID:32325033   PMID:35322233   PMID:36808153   PMID:37416774  


Genomics

Comparative Map Data
Syt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,574,319 - 134,680,887 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1134,574,415 - 134,690,331 (+)EnsemblGRCm39 Ensembl
GRCm381134,646,534 - 134,753,149 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,646,677 - 134,762,593 (+)EnsemblGRCm38mm10GRCm38
MGSCv371136,543,258 - 136,645,994 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361136,463,092 - 136,565,828 (+)NCBIMGSCv36mm8
Celera1137,257,554 - 137,373,520 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.24NCBI
SYT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381202,590,596 - 202,710,454 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1202,590,596 - 202,710,454 (-)EnsemblGRCh38hg38GRCh38
GRCh371202,559,724 - 202,679,582 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361200,831,511 - 200,946,168 (-)NCBINCBI36Build 36hg18NCBI36
Build 341199,296,544 - 199,411,202NCBI
Celera1175,686,865 - 175,807,438 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1173,725,569 - 173,845,371 (-)NCBIHuRef
CHM1_11203,981,971 - 204,101,776 (-)NCBICHM1_1
T2T-CHM13v2.01201,852,402 - 201,972,645 (-)NCBIT2T-CHM13v2.0
Syt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81348,639,634 - 48,749,814 (+)NCBIGRCr8
mRatBN7.21346,088,046 - 46,197,976 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1346,185,282 - 46,193,859 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1348,791,632 - 48,800,091 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01350,079,700 - 50,088,159 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01347,345,602 - 47,354,226 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01351,569,248 - 51,577,824 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1351,534,025 - 51,578,052 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01356,621,954 - 56,630,530 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,690,518 - 47,699,094 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11347,704,560 - 47,713,137 (+)NCBI
Celera1346,512,022 - 46,520,623 (+)NCBICelera
Cytogenetic Map13q13NCBI
Syt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540638,643,911 - 38,743,222 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540638,638,192 - 38,743,077 (-)NCBIChiLan1.0ChiLan1.0
SYT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2146,671,196 - 46,785,814 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1146,637,844 - 46,758,650 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01178,187,872 - 178,308,522 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11182,484,225 - 182,605,743 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1182,490,401 - 182,538,123 (-)Ensemblpanpan1.1panPan2
SYT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17497,387 - 509,338 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl7497,394 - 502,952 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha7478,659 - 557,321 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.07433,590 - 512,581 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl7433,409 - 512,622 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.17422,285 - 501,206 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.07531,125 - 609,898 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.07554,413 - 633,358 (+)NCBIUU_Cfam_GSD_1.0
Syt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934472,642,164 - 72,749,746 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365671,941,639 - 1,984,428 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365671,941,651 - 1,984,422 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1024,638,704 - 24,669,846 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11024,638,645 - 24,727,198 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21029,086,244 - 29,094,379 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SYT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12526,702,627 - 26,821,108 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2526,808,007 - 26,817,314 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605527,480,660 - 27,602,721 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Syt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248078,160,431 - 8,196,916 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248078,103,665 - 8,201,567 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Syt2
3264 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2404
Count of miRNA genes:810
Interacting mature miRNAs:1087
Transcripts:ENSMUST00000121990
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194127725148775742Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1102968534136968667Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109495943143495943Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109638262143638479Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110553179144553298Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110553179144553298Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112131005146131085Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116290836150290937Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118099720152099816Mouse
27226714Metcl1_mmetatarsal-calcaneal length 1, 5 week (mouse)1121727729139727738Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121727729153775746Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121727729153875746Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121727729164827569Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122027729164827569Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1122927738156927738Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128727737181327565Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129130858163130993Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131156308165139464Mouse
13524520Bodwtq1_mbody wweight QTL 1 (mouse)1131191160135621161Mouse
13513913Heal51_mwound healing/ regeneration 51 (mouse)1131780648135499606Mouse
14746980Manh50_mmandible shape 50 (mouse)1134131564168131564Mouse
13504831Bacszq1_mbaculum size QTL 1 (mouse)1134331161148128608Mouse

Markers in Region
BB351896  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381134,748,919 - 134,749,046UniSTSGRCm38
MGSCv371136,645,496 - 136,645,623UniSTSGRCm37
Celera1137,373,022 - 137,373,149UniSTS
Cytogenetic Map1E4UniSTS
cM Map173.5UniSTS
Whitehead/MRC_RH12638.37UniSTS
25.mHAa9h1.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381134,686,854 - 134,687,037UniSTSGRCm38
MGSCv371136,583,431 - 136,583,614UniSTSGRCm37
Celera1137,300,255 - 137,300,438UniSTS
Cytogenetic Map1E4UniSTS
cM Map173.5UniSTS
Whitehead_YAC1 UniSTS
MDB0795  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381134,752,850 - 134,753,045UniSTSGRCm38
MGSCv371136,649,427 - 136,649,622UniSTSGRCm37
Celera1137,376,930 - 137,377,145UniSTS
Cytogenetic Map1E4UniSTS
cM Map173.5UniSTS
Whitehead_YAC1 UniSTS
RH125086  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381134,752,864 - 134,752,948UniSTSGRCm38
MGSCv371136,649,441 - 136,649,525UniSTSGRCm37
Celera1137,376,944 - 137,377,028UniSTS
Cytogenetic Map1E4UniSTS
cM Map173.5UniSTS
Syt2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381134,747,618 - 134,748,276UniSTSGRCm38
MGSCv371136,644,195 - 136,644,853UniSTSGRCm37
Celera1137,371,726 - 137,372,378UniSTS
Cytogenetic Map1E4UniSTS
cM Map173.5UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001355726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB036512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB036513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB036514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC131591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF257303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF257304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI848167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ129987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D37793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000121990   ⟹   ENSMUSP00000112438
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1134,637,038 - 134,680,887 (+)Ensembl
GRCm38.p6 Ensembl1134,709,300 - 134,753,149 (+)Ensembl
RefSeq Acc Id: ENSMUST00000187702
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1134,676,315 - 134,690,331 (+)Ensembl
GRCm38.p6 Ensembl1134,748,577 - 134,762,593 (+)Ensembl
RefSeq Acc Id: ENSMUST00000187725   ⟹   ENSMUSP00000141156
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1134,574,415 - 134,669,567 (+)Ensembl
GRCm38.p6 Ensembl1134,646,677 - 134,741,829 (+)Ensembl
RefSeq Acc Id: ENSMUST00000188842   ⟹   ENSMUSP00000140081
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1134,574,419 - 134,677,155 (+)Ensembl
GRCm38.p6 Ensembl1134,646,681 - 134,749,417 (+)Ensembl
RefSeq Acc Id: NM_001355726   ⟹   NP_001342655
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,637,008 - 134,680,887 (+)NCBI
GRCm381134,709,300 - 134,753,149 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001421363   ⟹   NP_001408292
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,574,319 - 134,680,887 (+)NCBI
RefSeq Acc Id: NM_009307   ⟹   NP_033333
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,574,319 - 134,680,887 (+)NCBI
GRCm381134,646,612 - 134,753,149 (+)NCBI
MGSCv371136,543,258 - 136,645,994 (+)RGD
Celera1137,257,554 - 137,373,520 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006529324   ⟹   XP_006529387
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,670,683 - 134,680,887 (+)NCBI
GRCm381134,742,945 - 134,753,149 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036163153   ⟹   XP_036019046
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,663,930 - 134,680,887 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_033333   ⟸   NM_009307
- UniProtKB: Q8R0E1 (UniProtKB/Swiss-Prot),   P46097 (UniProtKB/Swiss-Prot),   A0A0R4J2C2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006529387   ⟸   XM_006529324
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001342655   ⟸   NM_001355726
- UniProtKB: Q8R0E1 (UniProtKB/Swiss-Prot),   P46097 (UniProtKB/Swiss-Prot),   A0A0R4J2C2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000140081   ⟸   ENSMUST00000188842
RefSeq Acc Id: ENSMUSP00000141156   ⟸   ENSMUST00000187725
RefSeq Acc Id: ENSMUSP00000112438   ⟸   ENSMUST00000121990
RefSeq Acc Id: XP_036019046   ⟸   XM_036163153
- Peptide Label: isoform X1
- UniProtKB: Q8R0E1 (UniProtKB/Swiss-Prot),   P46097 (UniProtKB/Swiss-Prot),   A0A0R4J2C2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001408292   ⟸   NM_001421363
- UniProtKB: A0A0R4J2C2 (UniProtKB/TrEMBL)
Protein Domains
C2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P46097-F1-model_v2 AlphaFold P46097 1-422 view protein structure

Promoters
RGD ID:6875026
Promoter ID:EPDNEW_M964
Type:initiation region
Name:Syt2_3
Description:Mus musculus synaptotagmin II , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M965  EPDNEW_M966  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381134,646,677 - 134,646,737EPDNEW
RGD ID:6875028
Promoter ID:EPDNEW_M965
Type:single initiation site
Name:Syt2_2
Description:Mus musculus synaptotagmin II , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M964  EPDNEW_M966  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381134,672,460 - 134,672,520EPDNEW
RGD ID:6875030
Promoter ID:EPDNEW_M966
Type:initiation region
Name:Syt2_1
Description:Mus musculus synaptotagmin II , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M964  EPDNEW_M965  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381134,709,276 - 134,709,336EPDNEW
RGD ID:6818565
Promoter ID:MM_KWN:2165
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_009307
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361136,542,801 - 136,543,301 (+)MPROMDB
RGD ID:6818564
Promoter ID:MM_KWN:2166
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000121990
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361136,605,416 - 136,605,916 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99666 AgrOrtholog
Ensembl Genes ENSMUSG00000026452 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000121990 ENTREZGENE
  ENSMUST00000121990.2 UniProtKB/TrEMBL
  ENSMUST00000187725.7 UniProtKB/TrEMBL
  ENSMUST00000188842 ENTREZGENE
  ENSMUST00000188842.7 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synaptotagmin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20980 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:99666 ENTREZGENE
NCBI Gene 20980 ENTREZGENE
PANTHER PTHR10024:SF223 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SYNAPTOTAGMIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Syt2 PhenoGen
PRINTS C2DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SYNAPTOTAGMN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J2C2 ENTREZGENE, UniProtKB/TrEMBL
  P46097 ENTREZGENE
  Q5DTI3_MOUSE UniProtKB/TrEMBL
  Q8R0E1 ENTREZGENE
  Q9JM87_MOUSE UniProtKB/TrEMBL
  SYT2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8R0E1 UniProtKB/Swiss-Prot