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Gene: Syt2 (synaptotagmin II) Mus musculus
Symbol: Syt2
Name: synaptotagmin II
Description: Exhibits anion binding activity and calcium ion binding activity. Involved in calcium-dependent activation of synaptic vesicle fusion. Localizes to axon; neuromuscular junction; and plasma membrane. Is expressed in several structures, including central nervous system; heart; integumental system; peripheral nervous system; and sensory organ. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 7. Orthologous to human SYT2 (synaptotagmin 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: IP4BP; KIAA4194; mKIAA4194; R74640; synaptotagmin 2; synaptotagmin-2; sytII
Homo sapiens (human) : SYT2 (synaptotagmin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Syt2 (synaptotagmin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Syt2 (synaptotagmin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SYT2 (synaptotagmin 2)
Canis lupus familiaris (dog) : SYT2 (synaptotagmin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Syt2 (synaptotagmin 2)
Sus scrofa (pig) : SYT2 (synaptotagmin 2)
Chlorocebus sabaeus (African green monkey) : SYT2 (synaptotagmin 2)
Heterocephalus glaber (naked mole-rat) : Syt2 (synaptotagmin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1134,646,677 - 134,762,593 (+)EnsemblGRCm38mm10GRCm38
GRCm381134,646,534 - 134,753,149 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371136,543,258 - 136,645,994 (+)NCBIGRCm37mm9NCBIm37
MGSCv361136,463,092 - 136,565,828 (+)NCBImm8
Celera1137,257,554 - 137,373,520 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Syt2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731270
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.