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Gene: Cit (citron) Mus musculus
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Symbol: Cit
Name: citron
RGD ID: 731049
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including generation of neurons; metaphase/anaphase transition of mitotic cell cycle; and mitotic sister chromatid segregation. Localizes to actin cytoskeleton; ruffle; and vacuole. Is expressed in several structures, including central nervous system; hemolymphoid system gland; respiratory system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 17. Orthologous to human CIT (citron rho-interacting serine/threonine kinase); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C030025P15Rik; Cit-; Cit-k; citron kinase; citron Rho-interacting kinase; citron-N; CRIK; CRIK-SK; rho-interacting, serine/threonine-protein kinase 21
Orthologs:
Homo sapiens (human) : CIT (citron rho-interacting serine/threonine kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cit (citron rho-interacting serine/threonine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cit (citron rho-interacting serine/threonine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : CIT (citron rho-interacting serine/threonine kinase)
Canis lupus familiaris (dog) : CIT (citron rho-interacting serine/threonine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cit (citron rho-interacting serine/threonine kinase)
Sus scrofa (pig) : CIT (citron rho-interacting serine/threonine kinase)
Chlorocebus sabaeus (African green monkey) : CIT (citron rho-interacting serine/threonine kinase)
Heterocephalus glaber (naked mole-rat) : Cit (citron rho-interacting serine/threonine kinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395115,983,284 - 116,147,012 (+)NCBI
GRCm385115,845,224 - 116,008,953 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5115,845,278 - 116,008,947 (+)EnsemblGRCm38mm10GRCm38
MGSCv375116,295,665 - 116,456,352 (+)NCBIGRCm37mm9NCBIm37
MGSCv365116,106,655 - 116,267,342 (+)NCBImm8
Celera5112,946,512 - 113,107,010 (+)NCBICelera
Cytogenetic Map5FNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cit
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731049
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.