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Gene: Cit (citron) Mus musculus
Symbol: Cit
Name: citron
RGD ID: 731049
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including generation of neurons; metaphase/anaphase transition of mitotic cell cycle; and mitotic sister chromatid segregation. Localizes to actin cytoskeleton; ruffle; and vacuole. Is expressed in several structures, including central nervous system; hemolymphoid system gland; respiratory system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 17. Orthologous to human CIT (citron rho-interacting serine/threonine kinase); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C030025P15Rik; Cit-; Cit-k; citron kinase; citron Rho-interacting kinase; citron-N; CRIK; CRIK-SK; rho-interacting, serine/threonine-protein kinase 21
Homo sapiens (human) : CIT (citron rho-interacting serine/threonine kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cit (citron rho-interacting serine/threonine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cit (citron rho-interacting serine/threonine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : CIT (citron rho-interacting serine/threonine kinase)
Canis lupus familiaris (dog) : CIT (citron rho-interacting serine/threonine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cit (citron rho-interacting serine/threonine kinase)
Sus scrofa (pig) : CIT (citron rho-interacting serine/threonine kinase)
Chlorocebus sabaeus (African green monkey) : CIT (citron rho-interacting serine/threonine kinase)
Heterocephalus glaber (naked mole-rat) : Cit (citron rho-interacting serine/threonine kinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm395115,983,284 - 116,147,012 (+)NCBI
GRCm385115,845,224 - 116,008,953 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5115,845,278 - 116,008,947 (+)EnsemblGRCm38mm10GRCm38
MGSCv375116,295,665 - 116,456,352 (+)NCBIGRCm37mm9NCBIm37
MGSCv365116,106,655 - 116,267,342 (+)NCBImm8
Celera5112,946,512 - 113,107,010 (+)NCBICelera
Cytogenetic Map5FNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cit
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731049
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.