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Gene: CIT (citron rho-interacting serine/threonine kinase) Homo sapiens
Symbol: CIT
Name: citron rho-interacting serine/threonine kinase
Description: Exhibits PDZ domain binding activity and scaffold protein binding activity. Involved in mitotic cytokinesis; neuron apoptotic process; and positive regulation of cytokinesis. Localizes to membrane. Implicated in primary autosomal recessive microcephaly 17.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CITK; citron (rho-interacting, serine/threonine kinase 21); citron Rho-interacting kinase; CRIK; KIAA0949; MCPH17; rho-interacting, serine/threonine kinase 21; serine/threonine kinase 21; serine/threonine-protein kinase 21; STK21
Mus musculus (house mouse) : Cit (citron)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cit (citron rho-interacting serine/threonine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cit (citron rho-interacting serine/threonine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : CIT (citron rho-interacting serine/threonine kinase)
Canis lupus familiaris (dog) : CIT (citron rho-interacting serine/threonine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cit (citron rho-interacting serine/threonine kinase)
Sus scrofa (pig) : CIT (citron rho-interacting serine/threonine kinase)
Chlorocebus sabaeus (African green monkey) : CIT (citron rho-interacting serine/threonine kinase)
Heterocephalus glaber (naked mole-rat) : Cit (citron rho-interacting serine/threonine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl12119,685,791 - 119,877,320 (-)EnsemblGRCh38hg38GRCh38
GRCh3812119,685,791 - 119,877,320 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712120,123,595 - 120,315,095 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612118,607,981 - 118,799,475 (-)NCBINCBI36hg18NCBI36
Build 3412118,586,317 - 118,777,812NCBI
Celera12119,756,651 - 119,948,207 (-)NCBI
Cytogenetic Map12q24.23NCBI
HuRef12117,131,727 - 117,325,161 (-)NCBIHuRef
CHM1_112120,091,103 - 120,282,752 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CIT
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731048
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.