Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: HRK (harakiri, BCL2 interacting protein) Homo sapiens
Symbol: HRK
Name: harakiri, BCL2 interacting protein
Description: Involved in positive regulation of protein complex assembly and positive regulation of release of cytochrome c from mitochondria. Localizes to the mitochondrion.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activator of apoptosis harakiri; activator of apoptosis Hrk; BCL2-interacting protein; BH3-interacting domain-containing protein 3; death protein 5; DP5; HARAKIRI; harakiri, BCL2 interacting protein (contains only BH3 domain); neuronal death protein DP5
Mus musculus (house mouse) : Hrk (harakiri, BCL2 interacting protein (contains only BH3 domain))  MGI  Alliance
Rattus norvegicus (Norway rat) : Hrk (harakiri, BCL2 interacting protein)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : HRK (harakiri, BCL2 interacting protein)
Canis lupus familiaris (dog) : HRK (harakiri, BCL2 interacting protein)
Sus scrofa (pig) : HRK (harakiri, BCL2 interacting protein)
Chlorocebus sabaeus (African green monkey) : HRK (harakiri, BCL2 interacting protein)
Heterocephalus glaber (naked mole-rat) : Hrk (harakiri, BCL2 interacting protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl12116,856,144 - 116,881,441 (-)Ensembl
GRCh3812116,856,144 - 116,881,441 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712117,298,225 - 117,319,232 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612115,783,410 - 115,803,615 (-)NCBINCBI36hg18NCBI36
Build 3412115,761,747 - 115,781,952NCBI
Celera12116,928,567 - 116,948,765 (-)NCBI
Cytogenetic Map12q24.22NCBI
HuRef12114,307,719 - 114,328,689 (-)NCBIHuRef
CHM1_112117,265,885 - 117,286,893 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HRK
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731025
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.