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Gene: DYNLL2 (dynein light chain LC8-type 2) Homo sapiens
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Symbol: DYNLL2
Name: dynein light chain LC8-type 2
Description: Predicted to contribute to ATP-dependent microtubule motor activity, plus-end-directed. Predicted to be involved in positive regulation of ATP-dependent microtubule motor activity, plus-end-directed. Localizes to the centrosome; glutamatergic synapse; and postsynapse; PARTICIPATES IN mitochondria transport pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one; 17beta-hydroxy-5alpha-androstan-3-one; 2-hydroxypropanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 8 kDa dynein light chain b; Dlc2; DLC8b; DNCL1B; dynein light chain 2; dynein light chain 2, cytoplasmic; dynein, light chain, LC8-type 2; MGC17810; radial spoke 22 homolog; RSPH22
Orthologs:
Mus musculus (house mouse) : Dynll2 (dynein light chain LC8-type 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dynll2 (dynein light chain LC8-type 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dynll2 (dynein light chain LC8-type 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DYNLL2 (dynein light chain LC8-type 2)
Canis lupus familiaris (dog) : DYNLL2 (dynein light chain LC8-type 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dynll2 (dynein light chain LC8-type 2)
Sus scrofa (pig) : DYNLL2 (dynein light chain LC8-type 2)
Chlorocebus sabaeus (African green monkey) : DYNLL2 (dynein light chain LC8-type 2)
Heterocephalus glaber (naked mole-rat) : Dynll2 (dynein light chain LC8-type 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1758,083,419 - 58,095,542 (+)Ensembl
GRCh381758,083,419 - 58,095,542 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371756,160,780 - 56,167,618 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361753,515,798 - 53,521,810 (+)NCBINCBI36hg18NCBI36
Build 341753,515,797 - 53,521,812NCBI
Celera1752,622,562 - 52,629,401 (+)NCBI
Cytogenetic Map17q22NCBI
HuRef1751,521,612 - 51,528,449 (+)NCBIHuRef
CHM1_11756,225,816 - 56,232,655 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DYNLL2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730979
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.