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Gene: HTR3B (5-hydroxytryptamine receptor 3B) Homo sapiens
Symbol: HTR3B
Name: 5-hydroxytryptamine receptor 3B
Description: Exhibits serotonin-gated cation-selective channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; nervous system process; and regulation of membrane potential. Localizes to cell surface and serotonin-activated cation-selective channel complex. Implicated in alcohol use disorder and mental depression.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5-HT3-B; 5-HT3B; 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic; 5-hydroxytryptamine 3 receptor B subunit; serotonin receptor 3B; serotonin-gated ion channel subunit
Mus musculus (house mouse) : Htr3b (5-hydroxytryptamine (serotonin) receptor 3B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Htr3b (5-hydroxytryptamine receptor 3B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr3b (5-hydroxytryptamine receptor 3B)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR3B (5-hydroxytryptamine receptor 3B)
Canis lupus familiaris (dog) : HTR3B (5-hydroxytryptamine receptor 3B)
Sus scrofa (pig) : HTR3B (5-hydroxytryptamine receptor 3B)
Chlorocebus sabaeus (African green monkey) : HTR3B (5-hydroxytryptamine receptor 3B)
Heterocephalus glaber (naked mole-rat) : Htr3b (5-hydroxytryptamine receptor 3B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl11113,904,677 - 113,949,078 (+)EnsemblGRCh38hg38GRCh38
GRCh3811113,898,923 - 113,949,119 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711113,775,518 - 113,817,283 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611113,280,799 - 113,322,493 (+)NCBINCBI36hg18NCBI36
Build 3411113,280,798 - 113,322,492NCBI
Celera11110,928,462 - 110,970,153 (+)NCBI
Cytogenetic Map11q23.2NCBI
HuRef11109,703,741 - 109,746,039 (+)NCBIHuRef
CHM1_111113,659,109 - 113,701,462 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HTR3B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730958
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.