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Gene: SEMA3A (semaphorin 3A) Homo sapiens
Symbol: SEMA3A
Name: semaphorin 3A
Description: Predicted to have chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Involved in negative regulation of neuron projection development; olfactory bulb development; and regulation of axon extension involved in axon guidance. Predicted to localize to axon; extracellular space; and integral component of plasma membrane. Implicated in hypogonadotropic hypogonadism 16 with or without anosmia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: coll-1; COLL1; collapsin 1; HH16; Hsema-I; Hsema-III; MGC133243; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; SEMA1; SEMAD; SEMAIII; SEMAL; semaphorin D; semaphorin III; semaphorin L; semaphorin-3A; semaphorin-like; SemD
Mus musculus (house mouse) : Sema3a (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sema3a (semaphorin 3A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sema3a (semaphorin 3A)
Pan paniscus (bonobo/pygmy chimpanzee) : SEMA3A (semaphorin 3A)
Canis lupus familiaris (dog) : SEMA3A (semaphorin 3A)
Sus scrofa (pig) : SEMA3A (semaphorin 3A)
Chlorocebus sabaeus (African green monkey) : SEMA3A (semaphorin 3A)
Heterocephalus glaber (naked mole-rat) : Sema3a (semaphorin 3A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl783,955,777 - 84,492,724 (-)EnsemblGRCh38hg38GRCh38
GRCh38783,955,777 - 84,515,189 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37783,587,659 - 84,122,040 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36783,425,595 - 83,662,153 (-)NCBINCBI36hg18NCBI36
Build 34783,235,140 - 83,468,560NCBI
Celera778,289,042 - 78,525,324 (-)NCBI
Cytogenetic Map7q21.11NCBI
HuRef778,196,709 - 78,433,239 (-)NCBIHuRef
CHM1_1783,517,590 - 83,754,442 (-)NCBICHM1_1
CRA_TCAGchr7v2782,919,781 - 83,156,009 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SEMA3A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730921
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-05-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.