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Gene: SDC4 (syndecan 4) Homo sapiens
Symbol: SDC4
Name: syndecan 4
Description: Exhibits identical protein binding activity and thrombospondin receptor activity. Involved in negative regulation of T cell proliferation; positive regulation of exosomal secretion; and positive regulation of extracellular exosome assembly. Localizes to the extracellular exosome. Biomarker of myocardial infarction.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: amphiglycan; MGC22217; ryudocan amphiglycan; ryudocan core protein; SYND4; syndecan 4 (amphiglycan, ryudocan); syndecan proteoglycan 4; syndecan-4
Mus musculus (house mouse) : Sdc4 (syndecan 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sdc4 (syndecan 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sdc4 (syndecan 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SDC4 (syndecan 4)
Canis lupus familiaris (dog) : SDC4 (syndecan 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sdc4 (syndecan 4)
Sus scrofa (pig) : SDC4 (syndecan 4)
Chlorocebus sabaeus (African green monkey) : SDC4 (syndecan 4)
Heterocephalus glaber (naked mole-rat) : Sdc4 (syndecan 4)
more info ...
Related Pseudogenes: SDC4P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2045,325,288 - 45,348,424 (-)Ensembl
GRCh382045,325,288 - 45,348,424 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372043,953,928 - 43,977,064 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,387,342 - 43,410,478 (-)NCBINCBI36hg18NCBI36
Build 342043,387,343 - 43,410,478NCBI
Celera2040,662,456 - 40,685,588 (-)NCBI
Cytogenetic Map20q13.12NCBI
HuRef2040,695,444 - 40,718,573 (-)NCBIHuRef
CHM1_12043,856,488 - 43,879,617 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SDC4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730877
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.