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Gene: SDC1 (syndecan 1) Homo sapiens
Symbol: SDC1
Name: syndecan 1
Description: Exhibits identical protein binding activity and protein C-terminus binding activity. Involved in positive regulation of exosomal secretion; positive regulation of extracellular exosome assembly; and striated muscle cell development. Localizes to the cell surface. Biomarker of Hodgkin's lymphoma and hyperglycemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; SDC; SYND1; syndecan; syndecan proteoglycan 1; syndecan-1
Mus musculus (house mouse) : Sdc1 (syndecan 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sdc1 (syndecan 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sdc1 (syndecan 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SDC1 (syndecan 1)
Canis lupus familiaris (dog) : SDC1 (syndecan 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sdc1 (syndecan 1)
Sus scrofa (pig) : SDC1 (syndecan 1)
Chlorocebus sabaeus (green monkey) : SDC1 (syndecan 1)
Heterocephalus glaber (naked mole-rat) : Sdc1 (syndecan 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl220,200,797 - 20,225,433 (-)Ensembl
GRCh38220,200,797 - 20,225,433 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37220,400,558 - 20,425,194 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36220,264,039 - 20,288,675 (-)NCBINCBI36hg18NCBI36
Build 34220,322,187 - 20,346,555NCBI
Celera220,262,845 - 20,287,481 (-)NCBI
Cytogenetic Map2p24.1NCBI
HuRef220,158,155 - 20,182,491 (-)NCBIHuRef
CHM1_1220,329,922 - 20,354,554 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SDC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730864
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.