Pax8 Mouse (S)-amphetamine increases expression EXP 6480464 Dextroamphetamine results in increased expression of PAX8 mRNA CTD PMID:12558987 Pax8 Mouse (S)-nicotine increases expression ISO PAX8 (Homo sapiens) 6480464 Nicotine results in increased expression of PAX8 mRNA CTD PMID:23825647 Pax8 Mouse (S)-nicotine decreases expression ISO Pax8 (Rattus norvegicus) 6480464 Nicotine results in decreased expression of PAX8 mRNA CTD PMID:26776438 Pax8 Mouse 1,2-dichloroethane increases expression EXP 6480464 ethylene dichloride results in increased expression of PAX8 mRNA CTD PMID:28960355 Pax8 Mouse 2,2',5,5'-tetrachlorobiphenyl increases expression ISO PAX8 (Homo sapiens) 6480464 2 more ... CTD PMID:36804509 Pax8 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PAX8 mRNA CTD PMID:24058054 Pax8 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PAX8 promoter] CTD PMID:19654925 Pax8 Mouse 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of PAX8 mRNA CTD PMID:30951980 Pax8 Mouse 5-aza-2'-deoxycytidine multiple interactions ISO PAX8 (Homo sapiens) 6480464 [Decitabine co-treated with Tretinoin] results in increased expression of PAX8 mRNA CTD PMID:19524134 Pax8 Mouse acetamide increases expression ISO Pax8 (Rattus norvegicus) 6480464 acetamide results in increased expression of PAX8 mRNA CTD PMID:31881176 Pax8 Mouse all-trans-retinoic acid multiple interactions ISO PAX8 (Homo sapiens) 6480464 [decitabine co-treated with Tretinoin] results in increased expression of PAX8 mRNA CTD PMID:19524134 Pax8 Mouse all-trans-retinoic acid multiple interactions EXP 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of PAX8 mRNA and [bisphenol S co-treated with Tretinoin] results in decreased expression of PAX8 mRNA CTD PMID:30951980 Pax8 Mouse all-trans-retinoic acid decreases expression ISO PAX8 (Homo sapiens) 6480464 Tretinoin results in decreased expression of PAX8 mRNA CTD PMID:21924320 Pax8 Mouse ammonium chloride affects expression ISO Pax8 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of PAX8 mRNA CTD PMID:16483693 Pax8 Mouse antirheumatic drug decreases expression ISO PAX8 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of PAX8 mRNA CTD PMID:24449571 Pax8 Mouse aristolochic acid A decreases expression ISO PAX8 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of PAX8 mRNA CTD PMID:33212167 Pax8 Mouse bathocuproine disulfonic acid multiple interactions ISO Pax8 (Rattus norvegicus) 6480464 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA] CTD PMID:11108245 Pax8 Mouse benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to PAX8 promoter] CTD PMID:19654925 Pax8 Mouse beta-lapachone decreases expression ISO PAX8 (Homo sapiens) 6480464 beta-lapachone results in decreased expression of PAX8 mRNA CTD PMID:38218311 Pax8 Mouse bis(2-ethylhexyl) phthalate multiple interactions ISO PAX8 (Homo sapiens) 6480464 [Diethylhexyl Phthalate results in increased abundance of mono(2-ethyl-5-hydroxyhexyl) phthalate] which results in increased expression of PAX8 mRNA and TSHR protein affects the reaction [Diethylhexyl Phthalate results in increased expression of PAX8 protein] CTD PMID:30543897 and PMID:34708313 Pax8 Mouse bis(2-ethylhexyl) phthalate decreases expression ISO Pax8 (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in decreased expression of PAX8 mRNA CTD PMID:36714560 Pax8 Mouse bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA] CTD PMID:32303808 Pax8 Mouse bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of PAX8 mRNA CTD PMID:32303808 Pax8 Mouse bis(2-ethylhexyl) phthalate increases expression ISO Pax8 (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in increased expression of PAX8 mRNA and Diethylhexyl Phthalate results in increased expression of PAX8 protein CTD PMID:30543897 and PMID:35810816 Pax8 Mouse bis(2-ethylhexyl) phthalate increases expression ISO PAX8 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of PAX8 mRNA and Diethylhexyl Phthalate results in increased expression of PAX8 protein CTD PMID:30543897 Pax8 Mouse bisphenol A increases expression ISO PAX8 (Homo sapiens) 6480464 bisphenol A results in increased expression of PAX8 mRNA CTD PMID:23238275 Pax8 Mouse bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PAX8 mRNA CTD PMID:32156529 Pax8 Mouse bisphenol A increases methylation ISO PAX8 (Homo sapiens) 6480464 bisphenol A results in increased methylation of PAX8 gene CTD PMID:31601247 Pax8 Mouse bisphenol A decreases expression ISO Pax8 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of PAX8 mRNA CTD PMID:25181051 Pax8 Mouse bisphenol A increases expression ISO Pax8 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of PAX8 mRNA and bisphenol A results in increased expression of PAX8 protein CTD PMID:23238275 and PMID:26827900 Pax8 Mouse bisphenol F decreases expression EXP 6480464 bisphenol F results in decreased expression of PAX8 mRNA CTD PMID:30951980 Pax8 Mouse bisphenol F multiple interactions EXP 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of PAX8 mRNA CTD PMID:30951980 Pax8 Mouse bromobenzene increases expression ISO Pax8 (Rattus norvegicus) 6480464 bromobenzene results in increased expression of PAX8 mRNA CTD PMID:32479839 Pax8 Mouse cadmium dichloride increases methylation ISO Pax8 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased methylation of PAX8 promoter CTD PMID:22457795 Pax8 Mouse cadmium dichloride increases expression ISO PAX8 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of PAX8 mRNA CTD PMID:38568856 Pax8 Mouse calcium atom affects expression ISO Pax8 (Rattus norvegicus) 6480464 Calcium affects the expression of PAX8 mRNA CTD PMID:15913539 Pax8 Mouse calcium(0) affects expression ISO Pax8 (Rattus norvegicus) 6480464 Calcium affects the expression of PAX8 mRNA CTD PMID:15913539 Pax8 Mouse cannabidiol affects methylation ISO Pax8 (Rattus norvegicus) 6480464 Cannabidiol affects the methylation of PAX8 gene CTD PMID:30521419 Pax8 Mouse carmustine decreases expression ISO PAX8 (Homo sapiens) 6480464 Carmustine results in decreased expression of PAX8 mRNA CTD PMID:15980968 Pax8 Mouse CGP 52608 multiple interactions ISO PAX8 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PAX8 gene] CTD PMID:28238834 Pax8 Mouse cisplatin affects response to substance ISO PAX8 (Homo sapiens) 6480464 PAX8 protein affects the susceptibility to Cisplatin CTD PMID:16217747 Pax8 Mouse cocaine increases expression ISO PAX8 (Homo sapiens) 6480464 Cocaine results in increased expression of PAX8 mRNA CTD PMID:12629581 Pax8 Mouse colforsin daropate hydrochloride increases expression ISO PAX8 (Homo sapiens) 6480464 Colforsin results in increased expression of PAX8 mRNA and Colforsin results in increased expression of PAX8 protein CTD PMID:15961562 Pax8 Mouse corn oil affects expression ISO Pax8 (Rattus norvegicus) 6480464 Corn Oil affects the expression of PAX8 mRNA CTD PMID:16360708 Pax8 Mouse DDE decreases expression ISO PAX8 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of PAX8 mRNA CTD PMID:38568856 Pax8 Mouse decabromodiphenyl ether increases expression ISO Pax8 (Rattus norvegicus) 6480464 decabromobiphenyl ether results in increased expression of PAX8 mRNA CTD PMID:23914054 Pax8 Mouse decabromodiphenyl ether decreases expression ISO Pax8 (Rattus norvegicus) 6480464 decabromobiphenyl ether results in decreased expression of PAX8 mRNA CTD PMID:30844666 Pax8 Mouse diallyl trisulfide increases expression ISO PAX8 (Homo sapiens) 6480464 diallyl trisulfide results in increased expression of PAX8 protein CTD PMID:33751676 Pax8 Mouse endosulfan decreases expression ISO Pax8 (Rattus norvegicus) 6480464 Endosulfan results in decreased expression of PAX8 mRNA CTD PMID:29391264 Pax8 Mouse ethylparaben increases expression ISO PAX8 (Homo sapiens) 6480464 ethyl-p-hydroxybenzoate results in increased expression of PAX8 mRNA CTD PMID:37690743 Pax8 Mouse flavonoids decreases expression ISO Pax8 (Rattus norvegicus) 6480464 Flavonoids results in decreased expression of PAX8 mRNA CTD PMID:18035473 Pax8 Mouse folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of PAX8 mRNA CTD PMID:25629700 Pax8 Mouse folic acid affects methylation ISO PAX8 (Homo sapiens) 6480464 Folic Acid affects the methylation of PAX8 gene CTD PMID:29546377 Pax8 Mouse furan increases expression ISO Pax8 (Rattus norvegicus) 6480464 furan results in increased expression of PAX8 mRNA CTD PMID:25539665 Pax8 Mouse glyphosate increases expression ISO Pax8 (Rattus norvegicus) 6480464 Glyphosate results in increased expression of PAX8 mRNA CTD PMID:36462676 Pax8 Mouse lead(0) decreases expression ISO PAX8 (Homo sapiens) 6480464 Lead results in decreased expression of PAX8 mRNA CTD PMID:19921347 Pax8 Mouse lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of PAX8 mRNA CTD PMID:12057914 Pax8 Mouse mono(2-ethyl-5-hydroxyhexyl) phthalate multiple interactions ISO PAX8 (Homo sapiens) 6480464 [Diethylhexyl Phthalate results in increased abundance of mono(2-ethyl-5-hydroxyhexyl) phthalate] which results in increased expression of PAX8 mRNA CTD PMID:34708313 Pax8 Mouse mono(2-ethylhexyl) phthalate decreases expression ISO PAX8 (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of PAX8 protein CTD PMID:36005737 Pax8 Mouse nicotine increases expression ISO PAX8 (Homo sapiens) 6480464 Nicotine results in increased expression of PAX8 mRNA CTD PMID:23825647 Pax8 Mouse nicotine decreases expression ISO Pax8 (Rattus norvegicus) 6480464 Nicotine results in decreased expression of PAX8 mRNA CTD PMID:26776438 Pax8 Mouse paracetamol decreases expression ISO PAX8 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of PAX8 mRNA CTD PMID:26690555 Pax8 Mouse paracetamol decreases expression ISO Pax8 (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of PAX8 mRNA CTD PMID:33387578 Pax8 Mouse paracetamol increases expression ISO PAX8 (Homo sapiens) 6480464 Acetaminophen results in increased expression of PAX8 mRNA CTD PMID:29067470 Pax8 Mouse perchlorate decreases expression ISO Pax8 (Rattus norvegicus) 6480464 perchlorate results in decreased expression of PAX8 mRNA CTD PMID:35385113 Pax8 Mouse perfluorobutanesulfonic acid affects expression ISO Pax8 (Rattus norvegicus) 6480464 perfluorobutanesulfonic acid affects the expression of PAX8 mRNA CTD PMID:22071372 Pax8 Mouse perfluorobutyric acid increases expression ISO Pax8 (Rattus norvegicus) 6480464 perfluorobutyric acid results in increased expression of PAX8 mRNA CTD PMID:22071372 Pax8 Mouse perfluorododecanoic acid increases expression ISO Pax8 (Rattus norvegicus) 6480464 perfluorododecanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 Pax8 Mouse perfluorohexanesulfonic acid increases expression ISO Pax8 (Rattus norvegicus) 6480464 perfluorohexanesulfonic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 Pax8 Mouse perfluorohexanesulfonic acid decreases expression ISO PAX8 (Homo sapiens) 6480464 perfluorohexanesulfonic acid results in decreased expression of PAX8 mRNA CTD PMID:25812627 Pax8 Mouse perfluorohexanoic acid increases expression ISO Pax8 (Rattus norvegicus) 6480464 perfluorohexanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 Pax8 Mouse perfluorononanoic acid increases expression ISO Pax8 (Rattus norvegicus) 6480464 perfluoro-n-nonanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 Pax8 Mouse perfluorononanoic acid decreases expression ISO PAX8 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of PAX8 mRNA CTD PMID:25812627 Pax8 Mouse perfluorooctane-1-sulfonic acid affects expression ISO Pax8 (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid affects the expression of PAX8 mRNA CTD PMID:22071372 Pax8 Mouse perfluorooctane-1-sulfonic acid decreases expression ISO PAX8 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of PAX8 mRNA CTD PMID:25812627 Pax8 Mouse perfluorooctanoic acid increases expression ISO Pax8 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in increased expression of PAX8 mRNA and perfluorooctanoic acid results in increased expression of PAX8 protein CTD PMID:22071372 and PMID:34246126 Pax8 Mouse perfluorooctanoic acid decreases expression ISO PAX8 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of PAX8 mRNA CTD PMID:25812627 Pax8 Mouse perfluorooctanoic acid increases expression ISO PAX8 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of PAX8 mRNA and perfluorooctanoic acid results in increased expression of PAX8 protein CTD PMID:34246126 Pax8 Mouse perfluoroundecanoic acid increases expression ISO Pax8 (Rattus norvegicus) 6480464 perfluoroundecanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 Pax8 Mouse potassium iodide multiple interactions ISO Pax8 (Rattus norvegicus) 6480464 Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 enhancer]] more ... CTD PMID:27568464 Pax8 Mouse pyrrolidine dithiocarbamate multiple interactions ISO Pax8 (Rattus norvegicus) 6480464 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA] and PAX8 protein inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of TPO promoter] CTD PMID:11108245 Pax8 Mouse pyrrolidine dithiocarbamate decreases expression ISO Pax8 (Rattus norvegicus) 6480464 pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA CTD PMID:11108245 Pax8 Mouse pyrrolidine dithiocarbamate decreases chemical synthesis ISO Pax8 (Rattus norvegicus) 6480464 pyrrolidine dithiocarbamic acid results in decreased chemical synthesis of PAX8 protein CTD PMID:11108245 Pax8 Mouse quercetin decreases expression ISO PAX8 (Homo sapiens) 6480464 Quercetin results in decreased expression of PAX8 mRNA CTD PMID:15309432 Pax8 Mouse resveratrol multiple interactions ISO PAX8 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of PAX8 mRNA and NOTCH1 mutant form inhibits the reaction [Resveratrol results in increased expression of PAX8 mRNA] CTD PMID:23557933 and PMID:23594881 Pax8 Mouse resveratrol decreases expression ISO Pax8 (Rattus norvegicus) 6480464 resveratrol results in decreased expression of PAX8 mRNA CTD PMID:28668442 Pax8 Mouse resveratrol increases expression ISO PAX8 (Homo sapiens) 6480464 resveratrol results in increased expression of PAX8 mRNA and resveratrol results in increased expression of PAX8 protein CTD PMID:23594881 Pax8 Mouse silicon dioxide increases expression ISO Pax8 (Rattus norvegicus) 6480464 Silicon Dioxide results in increased expression of PAX8 mRNA CTD PMID:32721576 Pax8 Mouse silicon dioxide decreases methylation ISO PAX8 (Homo sapiens) 6480464 Silicon Dioxide results in decreased methylation of PAX8 gene CTD PMID:34973136 Pax8 Mouse sirolimus multiple interactions ISO PAX8 (Homo sapiens) 6480464 Sirolimus promotes the reaction [TP73 protein affects the activity of PAX8 protein] CTD PMID:21245298 Pax8 Mouse sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of PAX8 mRNA CTD PMID:31558096 Pax8 Mouse sodium perchlorate increases expression ISO Pax8 (Rattus norvegicus) 6480464 sodium perchlorate results in increased expression of PAX8 protein CTD PMID:29139221 Pax8 Mouse streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA and Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA] CTD PMID:32303808 Pax8 Mouse thioacetamide increases expression ISO Pax8 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of PAX8 mRNA CTD PMID:34492290 Pax8 Mouse thiram increases expression ISO PAX8 (Homo sapiens) 6480464 Thiram results in increased expression of PAX8 mRNA CTD PMID:38568856 Pax8 Mouse trichloroethene increases expression ISO Pax8 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of PAX8 mRNA CTD PMID:33387578 Pax8 Mouse triptonide increases expression EXP 6480464 triptonide results in increased expression of PAX8 mRNA CTD PMID:33045310 Pax8 Mouse urethane decreases expression ISO PAX8 (Homo sapiens) 6480464 Urethane results in decreased expression of PAX8 mRNA CTD PMID:28818685 Pax8 Mouse valproic acid increases methylation ISO PAX8 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of PAX8 gene CTD PMID:29154799