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Gene: FNTA (farnesyltransferase, CAAX box, alpha) Homo sapiens
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Symbol: FNTA
Name: farnesyltransferase, CAAX box, alpha
Description: Exhibits protein prenyltransferase activity and tubulin binding activity. Predicted to contribute to CAAX-protein geranylgeranyltransferase activity. Involved in positive regulation of deacetylase activity; positive regulation of tubulin deacetylation; and protein prenylation. Localizes to the CAAX-protein geranylgeranyltransferase complex; microtubule associated complex; and protein farnesyltransferase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: farnesyl-protein transferase alpha-subunit; FPTA; FTase-alpha; GGTase-I-alpha; MGC99680; PGGT1A; protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; protein prenyltransferase alpha subunit repeat containing 2; PTAR2; ras proteins prenyltransferase subunit alpha; type I protein geranyl-geranyltransferase alpha subunit
Orthologs:
Mus musculus (house mouse) : Fnta (farnesyltransferase, CAAX box, alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fnta (farnesyltransferase, CAAX box, alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fnta (farnesyltransferase, CAAX box, alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : FNTA (farnesyltransferase, CAAX box, alpha)
Canis lupus familiaris (dog) : FNTA (farnesyltransferase, CAAX box, alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fnta (farnesyltransferase, CAAX box, alpha)
Sus scrofa (pig) : FNTA (farnesyltransferase, CAAX box, alpha)
Chlorocebus sabaeus (green monkey) : FNTA (farnesyltransferase, CAAX box, alpha)
more info ...
Related Pseudogenes: FNTAP1   FNTAP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl843,034,194 - 43,085,788 (+)Ensembl
GRCh38843,056,299 - 43,085,788 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37842,911,442 - 42,940,931 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36843,030,599 - 43,060,088 (+)NCBINCBI36hg18NCBI36
Build 34843,030,640 - 43,060,080NCBI
Celera841,859,884 - 41,889,630 (+)NCBI
Cytogenetic Map8p11.21NCBI
HuRef841,434,064 - 41,463,781 (+)NCBIHuRef
CHM1_1842,958,364 - 42,987,853 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on FNTA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730816
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.