Synj2_v3 (synaptojanin 2, variant 3) - Rat Genome Database

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Gene: Synj2_v3 (synaptojanin 2, variant 3) Rattus norvegicus
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Symbol: Synj2_v3
Name: synaptojanin 2, variant 3
RGD ID: 728898
Description: binds both amphiphysin and endophilin
ENCODES an splice that exhibits SH3 domain binding; FOUND IN axon terminus; cytoplasmic microtubule; ruffle membrane
Type: splice  of Synj2  
Previously known as: synaptojanin 2B2; Synj2B2
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
RGSC_v3.1140,766,738 - 40,820,945 (+)NCBI


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Recruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein. Nemoto Y and De Camilli P, EMBO J 1999 Jun 1;18(11):2991-3006.
2. Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals. Nemoto Y, etal., J Biol Chem 2001 Nov 2;276(44):41133-42.

Genomics


Expression


Sequence

Nucleotide Sequences
GenBank Nucleotide AY034051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information

Database Acc Id Source(s)
BIND 130421
  130568
  130569
  134433
  134434
  134436


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-09-02 Synj2_v3  synaptojanin 2, variant 3  Synj2_v3  synaptojanin 2, varient 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Synj2_v3  synaptojanin 2, varient 3    synaptojanin 2, variant 3  Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_process plays a role in synaptic vesicle recycling by clathrin-mediated endocytosis and proper synaptic transmission of nerve terminals, and neurons 628465
gene_protein 1496 amino acids with predicted molecular weight of 165 kDa 628465