Brca1<i><sup>m1Uwm</sup></i> (BRCA1, DNA repair associated; mutation 1, University of Wisconsin-Madison) - Rat Genome Database

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Gene: Brca1m1Uwm (BRCA1, DNA repair associated; mutation 1, University of Wisconsin-Madison) Rattus norvegicus
Analyze
Symbol: Brca1m1Uwm
Name: BRCA1, DNA repair associated; mutation 1, University of Wisconsin-Madison
RGD ID: 728298
Description: produced by N-ethyl-N-nitrosourea (ENU)-induced germline mutations in Sprague Dawley (SD) rats; mutation from A to G at the exon 21/22 border causes a frameshift and premature stop codon
Type: allele  of Brca1  
Previously known as: Brca1m1Uwm; Brca1m1Uwm
Is Marker For: Strains:   SD-Brca1m1Uwm  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
RGSC_v3.11090,586,742 - 90,588,138 (-)NCBI


References

References - curated
# Reference Title Reference Citation
1. Production of knockout rats using ENU mutagenesis and a yeast-based screening assay. Zan Y, etal., Nat Biotechnol 2003 Jun;21(6):645-51.

Genomics


Related Rat Strains
The following Strains have been annotated to Brca1m1Uwm


Expression


Sequence

Nucleotide Sequences
GenBank Nucleotide AF080590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2007-04-12 Brca1m1Uwm    Brca1m1Uwm  breast cancer 1, mutation 1, University of Wisconsin-Madison  Symbol updated 737654 APPROVED
2004-12-14 Brca1m1Uwm  breast cancer 1, mutation 1, University of Wisconsin-Madison      Symbol and Name status set to approved 1299863 APPROVED