Tnni3k (TNNI3 interacting kinase) - Rat Genome Database

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Gene: Tnni3k (TNNI3 interacting kinase) Rattus norvegicus
Analyze
Symbol: Tnni3k
Name: TNNI3 interacting kinase
RGD ID: 727908
Description: Predicted to enable several functions, including RNA polymerase II-specific DNA-binding transcription factor binding activity; protein C-terminus binding activity; and troponin I binding activity. Predicted to be involved in protein phosphorylation; regulation of heart contraction; and regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to several human genes including TNNI3K (TNNI3 interacting kinase); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; copper atom.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cardiac ankyrin repeat kinase; Cark; serine/threonine-protein kinase TNNI3K; TNNI3-interacting kinase
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22243,737,346 - 244,005,319 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2243,710,950 - 244,005,268 (-)Ensembl
Rnor_6.02261,069,210 - 261,337,294 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2261,069,203 - 261,337,163 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02279,730,855 - 279,999,134 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42252,627,444 - 252,824,416 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12252,942,037 - 252,962,090 (+)NCBI
Celera2235,659,697 - 235,927,289 (-)NCBICelera
Cytogenetic Map2q45NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO,ISS)
nucleus  (IBA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I. Zhao Y, etal., J Mol Med 2003 May;81(5):297-304. Epub 2003 Apr 30.
Additional References at PubMed
PMID:12477932   PMID:18205602   PMID:23236294   PMID:23369981   PMID:23472207   PMID:24925317  


Genomics

Comparative Map Data
Tnni3k
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22243,737,346 - 244,005,319 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2243,710,950 - 244,005,268 (-)Ensembl
Rnor_6.02261,069,210 - 261,337,294 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2261,069,203 - 261,337,163 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02279,730,855 - 279,999,134 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42252,627,444 - 252,824,416 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12252,942,037 - 252,962,090 (+)NCBI
Celera2235,659,697 - 235,927,289 (-)NCBICelera
Cytogenetic Map2q45NCBI
TNNI3K
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38174,235,387 - 74,544,428 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl174,235,387 - 74,544,428 (+)EnsemblGRCh38hg38GRCh38
GRCh37174,701,071 - 75,010,112 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36174,473,673 - 74,782,696 (+)NCBINCBI36hg18NCBI36
Build 34174,413,105 - 74,722,129NCBI
Celera172,909,510 - 73,255,421 (+)NCBI
Cytogenetic Map1p31.1NCBI
HuRef172,835,865 - 73,144,630 (+)NCBIHuRef
CHM1_1174,816,721 - 75,125,605 (+)NCBICHM1_1
T2T-CHM13v2.0174,076,908 - 74,385,812 (+)NCBI
Tnni3k
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393154,491,928 - 154,761,044 (-)NCBIGRCm39mm39
GRCm39 Ensembl3154,491,928 - 154,761,044 (-)Ensembl
GRCm383154,786,291 - 155,055,407 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3154,786,291 - 155,055,407 (-)EnsemblGRCm38mm10GRCm38
MGSCv373154,449,255 - 154,718,371 (-)NCBIGRCm37mm9NCBIm37
MGSCv363154,721,595 - 154,990,700 (-)NCBImm8
Celera3161,244,354 - 161,513,160 (-)NCBICelera
Cytogenetic Map3H4NCBI
TNNI3K
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1175,440,781 - 75,747,682 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl175,403,555 - 75,747,240 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0173,464,364 - 73,772,977 (+)NCBIMhudiblu_PPA_v0panPan3
TNNI3K
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1671,825,853 - 72,107,832 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl671,815,734 - 72,119,476 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha674,489,520 - 74,761,768 (-)NCBI
ROS_Cfam_1.0672,463,781 - 72,703,848 (-)NCBI
ROS_Cfam_1.0 Ensembl672,419,208 - 72,703,805 (-)Ensembl
UMICH_Zoey_3.1671,913,206 - 72,224,860 (-)NCBI
UNSW_CanFamBas_1.0671,904,267 - 72,144,070 (-)NCBI
UU_Cfam_GSD_1.0672,399,222 - 72,639,531 (-)NCBI
Tnni3k
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505886,154,293 - 86,333,794 (+)NCBI
SpeTri2.0NW_0049365711,559,845 - 1,843,985 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC102164667
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.16138,634,770 - 138,914,194 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26128,498,341 - 128,553,755 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Position Markers
D2Got363  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22243,780,563 - 243,780,713 (+)MAPPERmRatBN7.2
Rnor_6.02261,112,080 - 261,112,229NCBIRnor6.0
Rnor_5.02279,773,723 - 279,773,872UniSTSRnor5.0
RGSC_v3.42252,671,448 - 252,671,597UniSTSRGSC3.4
Celera2235,702,645 - 235,702,794UniSTS
Cytogenetic Map2q45UniSTS
RH128803  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22243,737,357 - 243,737,549 (+)MAPPERmRatBN7.2
Rnor_6.02261,069,217 - 261,069,408NCBIRnor6.0
Rnor_5.02279,730,860 - 279,731,051UniSTSRnor5.0
RGSC_v3.42252,627,449 - 252,627,640UniSTSRGSC3.4
Celera2235,659,702 - 235,659,893UniSTS
RH 3.4 Map21640.0UniSTS
Cytogenetic Map2q45UniSTS
AU048026  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22243,912,810 - 243,913,009 (+)MAPPERmRatBN7.2
Rnor_6.02261,244,679 - 261,244,877NCBIRnor6.0
Rnor_5.02279,906,322 - 279,906,520UniSTSRnor5.0
RGSC_v3.42252,804,232 - 252,804,430UniSTSRGSC3.4
Celera2235,834,871 - 235,835,069UniSTS
Cytogenetic Map2q45UniSTS
BE100289  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22243,807,263 - 243,807,427 (+)MAPPERmRatBN7.2
Rnor_6.02261,139,064 - 261,139,227NCBIRnor6.0
Rnor_5.02279,800,707 - 279,800,870UniSTSRnor5.0
RGSC_v3.42252,697,346 - 252,697,509UniSTSRGSC3.4
Celera2235,729,322 - 235,729,485UniSTS
RH 3.4 Map21629.7UniSTS
Cytogenetic Map2q45UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
9587428Epfw6Epididymal fat weight QTL 67.470.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)2223389739249053267Rat
7411555Bw132Body weight QTL 1320.001body mass (VT:0001259)body weight gain (CMO:0000420)2223389739249053267Rat
631563Hcuc3Hepatic copper content QTL 33.87hepatic copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)2229059610249053267Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:37
Interacting mature miRNAs:37
Transcripts:ENSRNOT00000030341
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 33
Low 10 3 1 5 1 2 20 7 8
Below cutoff 19 6 13 6 8 8 53 11 16 3 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000030341   ⟹   ENSRNOP00000031479
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2243,737,353 - 244,005,268 (-)Ensembl
Rnor_6.0 Ensembl2261,069,203 - 261,337,163 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102655   ⟹   ENSRNOP00000095720
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2243,737,353 - 244,005,268 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103906   ⟹   ENSRNOP00000091387
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2243,763,384 - 244,005,268 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000120189   ⟹   ENSRNOP00000082900
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2243,710,950 - 244,005,268 (-)Ensembl
RefSeq Acc Id: NM_181769   ⟹   NP_861434
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22243,737,353 - 244,005,268 (-)NCBI
Rnor_6.02261,069,212 - 261,337,132 (-)NCBI
Rnor_5.02279,730,855 - 279,999,134 (-)NCBI
RGSC_v3.42252,627,444 - 252,824,416 (-)RGD
Celera2235,659,697 - 235,927,289 (-)RGD
Sequence:
RefSeq Acc Id: XM_008761563   ⟹   XP_008759785
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22243,737,346 - 244,005,319 (-)NCBI
Rnor_6.02261,069,210 - 261,337,291 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102111   ⟹   XP_038958039
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22243,824,444 - 244,005,319 (-)NCBI
Protein Sequences
Protein RefSeqs NP_861434 (Get FASTA)   NCBI Sequence Viewer  
  XP_008759785 (Get FASTA)   NCBI Sequence Viewer  
  XP_038958039 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP72031 (Get FASTA)   NCBI Sequence Viewer  
  EDL82543 (Get FASTA)   NCBI Sequence Viewer  
  Q7TQP6 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_861434   ⟸   NM_181769
- UniProtKB: Q7TQP6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008759785   ⟸   XM_008761563
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000031479   ⟸   ENSRNOT00000030341
RefSeq Acc Id: XP_038958039   ⟸   XM_039102111
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000095720   ⟸   ENSRNOT00000102655
RefSeq Acc Id: ENSRNOP00000082900   ⟸   ENSRNOT00000120189
RefSeq Acc Id: ENSRNOP00000091387   ⟸   ENSRNOT00000103906
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TQP6-F1-model_v2 AlphaFold Q7TQP6 1-835 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727908 AgrOrtholog
BioCyc Gene G2FUF-50734 BioCyc
Ensembl Genes ENSRNOG00000028225 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000031479 ENTREZGENE
  ENSRNOP00000031479.5 UniProtKB/TrEMBL
  ENSRNOP00000082900.1 UniProtKB/TrEMBL
  ENSRNOP00000091387.1 UniProtKB/TrEMBL
  ENSRNOP00000095720.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030341 ENTREZGENE
  ENSRNOT00000030341.7 UniProtKB/TrEMBL
  ENSRNOT00000102655.1 UniProtKB/TrEMBL
  ENSRNOT00000103906.1 UniProtKB/TrEMBL
  ENSRNOT00000120189.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:295531 UniProtKB/Swiss-Prot
NCBI Gene 295531 ENTREZGENE
Pfam Ank UniProtKB/Swiss-Prot
  Ank_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tnni3k PhenoGen
PRINTS ANKYRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ANK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZUY2_RAT UniProtKB/TrEMBL
  A0A8I6AED2_RAT UniProtKB/TrEMBL
  A0A8I6AU11_RAT UniProtKB/TrEMBL
  F1LPM9_RAT UniProtKB/TrEMBL
  Q7TQP6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-03 Tnni3k  TNNI3 interacting kinase  Cark  cardiac ankyrin repeat kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Cark  cardiac ankyrin repeat kinase      Symbol and Name status set to approved 1299863 APPROVED