URAHP (urate (hydroxyiso-) hydrolase, pseudogene) - Rat Genome Database

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Gene: URAHP (urate (hydroxyiso-) hydrolase, pseudogene) Homo sapiens
Analyze
Symbol: URAHP
Name: urate (hydroxyiso-) hydrolase, pseudogene
RGD ID: 7247048
HGNC Page HGNC
Description: Predicted to enable hydroxyisourate hydrolase activity. Predicted to be involved in allantoin metabolic process; purine-containing compound catabolic process; and urate catabolic process. Predicted to be active in peroxisome; INTERACTS WITH benzo[a]pyrene; fipronil; N,N-diethyl-m-toluamide.
Type: pseudo
RefSeq Status: VALIDATED
Also known as: URAH
RGD Orthologs
Mouse
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1690,039,761 - 90,047,773 (-)EnsemblGRCh38hg38GRCh38
GRCh381690,039,761 - 90,047,783 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371690,106,169 - 90,114,191 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361688,637,096 - 88,641,692 (-)NCBINCBI36hg18NCBI36
Celera1675,170,699 - 75,178,567 (-)NCBI
Cytogenetic Map16q24.3NCBI
HuRef1675,797,784 - 75,805,903 (-)NCBIHuRef
CHM1_11691,517,951 - 91,525,969 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
peroxisome  (ISO)

Molecular Function

References

Additional References at PubMed
PMID:12477932   PMID:16462750   PMID:20106906  


Genomics

Comparative Map Data
URAHP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1690,039,761 - 90,047,773 (-)EnsemblGRCh38hg38GRCh38
GRCh381690,039,761 - 90,047,783 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371690,106,169 - 90,114,191 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361688,637,096 - 88,641,692 (-)NCBINCBI36hg18NCBI36
Celera1675,170,699 - 75,178,567 (-)NCBI
Cytogenetic Map16q24.3NCBI
HuRef1675,797,784 - 75,805,903 (-)NCBIHuRef
CHM1_11691,517,951 - 91,525,969 (-)NCBICHM1_1
Urah
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,414,936 - 140,417,884 (+)NCBIGRCm39mm39
GRCm39 Ensembl7140,414,931 - 140,417,879 (+)Ensembl
GRCm387140,834,958 - 140,837,971 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7140,835,018 - 140,837,966 (+)EnsemblGRCm38mm10GRCm38
MGSCv377148,021,395 - 148,023,867 (+)NCBIGRCm37mm9NCBIm37
MGSCv367140,686,338 - 140,689,289 (+)NCBImm8
Celera7140,627,819 - 140,630,291 (+)NCBICelera
Cytogenetic Map7F4NCBI

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1568
Count of miRNA genes:752
Interacting mature miRNAs:903
Transcripts:ENST00000409768, ENST00000409873, ENST00000517889, ENST00000521551, ENST00000610227
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 3 7 432 11 10 50 3 272 6 263 257 2 49
Low 2354 2213 1265 600 668 441 4157 2016 3337 381 1146 1284 169 1204 2626 3
Below cutoff 71 701 23 11 1030 13 147 166 97 30 37 56 112

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000409768
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1690,043,429 - 90,044,610 (-)Ensembl
RefSeq Acc Id: ENST00000409873
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1690,039,761 - 90,047,625 (-)Ensembl
RefSeq Acc Id: ENST00000517889
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1690,042,902 - 90,047,773 (-)Ensembl
RefSeq Acc Id: ENST00000521551
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1690,043,802 - 90,047,190 (-)Ensembl
RefSeq Acc Id: ENST00000610227
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1690,043,914 - 90,047,597 (-)Ensembl
RefSeq Acc Id: NR_027335
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381690,039,761 - 90,047,625 (-)NCBI
GRCh371690,106,169 - 90,114,191 (-)NCBI
HuRef1675,797,784 - 75,805,903 (-)NCBI
CHM1_11691,517,951 - 91,525,811 (-)NCBI
Sequence:
RefSeq Acc Id: NR_027336
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381690,042,902 - 90,047,783 (-)NCBI
GRCh371690,106,169 - 90,114,191 (-)NCBI
HuRef1675,797,784 - 75,805,903 (-)NCBI
CHM1_11691,521,092 - 91,525,969 (-)NCBI
Sequence:
Protein Sequences
GenBank Protein BAH14124 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 16q24.3(chr16:89830573-90044855)x1 copy number loss See cases [RCV000148110] Chr16:89830573..90044855 [GRCh38]
Chr16:89896981..90111263 [GRCh37]
Chr16:88424482..88638764 [NCBI36]
Chr16:16q24.3
uncertain significance
GRCh38/hg38 16q24.1-24.3(chr16:84707538-90081985)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052425]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052425]|See cases [RCV000052425] Chr16:84707538..90081985 [GRCh38]
Chr16:84741144..90148393 [GRCh37]
Chr16:83298645..88675894 [NCBI36]
Chr16:16q24.1-24.3
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:43695 AgrOrtholog
COSMIC URAHP COSMIC
Ensembl Genes ENSG00000222019 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000409873 ENTREZGENE
  ENST00000517889 ENTREZGENE
GTEx ENSG00000222019 GTEx
HGNC ID HGNC:43695 ENTREZGENE
Human Proteome Map URAHP Human Proteome Map
NCBI Gene URAHP ENTREZGENE
OMIM 615805 OMIM