Esp24 (exocrine gland secreted peptide 24) - Rat Genome Database

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Gene: Esp24 (exocrine gland secreted peptide 24) Mus musculus
Analyze
Symbol: Esp24
Name: exocrine gland secreted peptide 24
RGD ID: 7177922
MGI Page MGI
Description: Enables pheromone activity. Acts upstream of or within signal transduction. Located in extracellular space.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: exocrine gland-secreting peptide 24; Gm21947
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391739,347,586 - 39,351,118 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1739,347,586 - 39,351,118 (+)EnsemblGRCm39 Ensembl
GRCm381739,036,695 - 39,040,227 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1739,036,695 - 39,040,227 (+)EnsemblGRCm38mm10GRCm38
Celera1742,465,490 - 42,469,022 (+)NCBICelera
Cytogenetic Map17B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
pheromone activity  (IDA,ISA,ISS)

References
Additional References at PubMed
PMID:17935991   PMID:23094077   PMID:24089208  


Genomics

Variants

.
Variants in Esp24
87 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:33
Count of miRNA genes:32
Interacting mature miRNAs:33
Transcripts:ENSMUST00000180245
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172650533741105037Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173596629469966424Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173678974370789743Mouse
1301474Hcbip2_mhexachlorobenzene induced porphyria 2 (mouse)Not determined173779305545622654Mouse
1300592Pcyts5_mplasmacytoma susceptibility 5 (mouse)Not determined173871288772712970Mouse
10755525Lymph2_mlymphocyte differential 2 (mouse)173880562672805626Mouse
10755534Lymph4_mlymphocyte differential 4 (mouse)173880562672805626Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000180245   ⟹   ENSMUSP00000137640
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1739,349,176 - 39,351,008 (+)Ensembl
GRCm38.p6 Ensembl1739,038,285 - 39,040,117 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232955   ⟹   ENSMUSP00000156516
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1739,347,586 - 39,351,118 (+)Ensembl
GRCm38.p6 Ensembl1739,036,695 - 39,040,227 (+)Ensembl
RefSeq Acc Id: NM_001256050   ⟹   NP_001242979
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391739,347,586 - 39,351,118 (+)NCBI
GRCm381739,036,695 - 39,040,227 (+)NCBI
Celera1742,465,490 - 42,469,022 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001242979 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAF92739 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000137640.2
  ENSMUSP00000156516
  ENSMUSP00000156516.2
RefSeq Acc Id: NP_001242979   ⟸   NM_001256050
- Peptide Label: precursor
- UniProtKB: A8R0V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000156516   ⟸   ENSMUST00000232955
RefSeq Acc Id: ENSMUSP00000137640   ⟸   ENSMUST00000180245

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A8R0V6-F1-model_v2 AlphaFold A8R0V6 1-68 view protein structure

Promoters
RGD ID:13676064
Promoter ID:EPDNEW_M22181
Type:single initiation site
Name:Esp24_1
Description:Mus musculus exocrine gland secreted peptide 24 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381739,036,695 - 39,036,755EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000095625 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000180245.2 UniProtKB/TrEMBL
  ENSMUST00000232955 ENTREZGENE
  ENSMUST00000232955.2 UniProtKB/TrEMBL
InterPro Esp1/Esp22 UniProtKB/TrEMBL
KEGG Report mmu:100126776 UniProtKB/TrEMBL
MGD MGI:5439398 ENTREZGENE
NCBI Gene Gm21947 ENTREZGENE
Pfam ESP UniProtKB/TrEMBL
PhenoGen Esp24 PhenoGen
UniProt A8R0V6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-05 Esp24  exocrine gland secreted peptide 24  Gm21947  predicted gene, 21947  Symbol and/or name change 5135510 APPROVED