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Gene: Lzts1 (leucine zipper tumor suppressor 1) Rattus norvegicus
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Symbol: Lzts1
Name: leucine zipper tumor suppressor 1
Description: Predicted to have microtubule binding activity. Involved in regulation of dendrite morphogenesis and regulation of synaptic plasticity. Localizes to several cellular components, including the apical plasma membrane; dendrite; and postsynaptic density. Human ortholog(s) of this gene implicated in esophageal cancer and squamous cell carcinoma. Orthologous to human LZTS1 (leucine zipper tumor suppressor 1); INTERACTS WITH 1-naphthyl isothiocyanate; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: leucine zipper putative tumor suppressor 1; leucine zipper, putative tumor suppressor 1; PSD-Zip70; Psdzip70; similar to leucine zipper putative tumor suppressor 1
Orthologs:
Homo sapiens (human) : LZTS1 (leucine zipper tumor suppressor 1)  HGNC  Alliance
Mus musculus (house mouse) : Lzts1 (leucine zipper, putative tumor suppressor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lzts1 (leucine zipper tumor suppressor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LZTS1 (leucine zipper tumor suppressor 1)
Canis lupus familiaris (dog) : LZTS1 (leucine zipper tumor suppressor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lzts1 (leucine zipper tumor suppressor 1)
Sus scrofa (pig) : LZTS1 (leucine zipper tumor suppressor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01622,250,452 - 22,306,667 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1622,250,470 - 22,306,662 (+)Ensembl
Rnor_5.01622,147,127 - 22,202,136 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41622,243,137 - 22,300,978 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11622,243,134 - 22,300,975 (+)NCBI
Celera1620,519,932 - 20,575,243 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lzts1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 708565
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.