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Gene: Akap14 (A-kinase anchoring protein 14) Rattus norvegicus

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Symbol:

Akap14

Name:

A-kinase anchoring protein 14

RGD ID:

708510

Description:

Enables protein kinase A binding activity. Involved in spermatogenesis. Located in sperm fibrous sheath. Orthologous to human AKAP14 (A-kinase anchoring protein 14); PARTICIPATES IN protein kinase A (PKA) signaling pathway; INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

A kinase (PRKA) anchor protein 14; A-kinase anchor protein 14; AKAP-14; LOC60332; TAKAP-1.2; testis-specific A-kinase-anchoring protein TAKAP-80; Testis-specific A-kinase-anchoring-protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AKAP14 (A-kinase anchoring protein 14)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Akap14 (A kinase anchor protein 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Akap14 (A-kinase anchoring protein 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AKAP14 (A-kinase anchoring protein 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AKAP14 (A-kinase anchoring protein 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Akap14 (A-kinase anchoring protein 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AKAP14 (A-kinase anchoring protein 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	AKAP14 (A-kinase anchoring protein 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Akap14 (A-kinase anchoring protein 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DEF6 (DEF6 guanine nucleotide exchange factor)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	AKAP14 (A-kinase anchoring protein 14)	Alliance	DIOPT (Ensembl Compara\|HGNC\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Akap14 (A kinase anchor protein 14)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkeyp-81f3.4	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8252	Alliance	DIOPT (OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	akap14	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	121,261,195 - 121,276,376 (-)	NCBI		GRCr8
mRatBN7.2	X	116,395,512 - 116,410,697 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	116,395,516 - 116,410,697 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	118,499,111 - 118,514,245 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	122,068,246 - 122,083,383 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	119,614,305 - 119,629,441 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	123,773,430 - 123,788,898 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	123,773,430 - 123,788,898 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	123,909,957 - 123,925,151 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	7,744,305 - 7,759,380 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	7,749,860 - 7,764,934 (+)	NCBI
Celera	X	115,623,134 - 115,638,227 (-)	NCBI		Celera
Cytogenetic Map	X	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal hemophilia A (ISO)

Danon disease (ISO)

factor VIII deficiency (ISO)

syndromic X-linked intellectual disability 14 (ISO)

syndromic X-linked intellectual disability Cabezas type (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

Aflatoxin B2 alpha (ISO)

amitrole (EXP)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

carbon nanotube (ISO)

dichloroacetic acid (ISO)

entinostat (ISO)

epoxiconazole (ISO)

fenvalerate (EXP)

folic acid (ISO)

methapyrilene (ISO)

methimazole (EXP)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

testosterone (EXP)

titanium dioxide (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

spermatogenesis (IEP)

Cellular Component

axoneme (ISO)

cAMP-dependent protein kinase complex (IBA,ISO)

cytoplasm (IEA)

sperm fibrous sheath (IDA)

Molecular Function

protein binding (ISO)

protein kinase A binding (IPI)

protein kinase A regulatory subunit binding (IBA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

protein kinase A (PKA) signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	A-kinase anchoring proteins: from protein complexes to physiology and disease.	Carnegie GK, etal., IUBMB Life. 2009 Apr;61(4):394-406.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Cloning and characterization of a testis-specific, developmentally regulated A-kinase-anchoring protein (TAKAP-80) present on the fibrous sheath of rat sperm.	Mei X, etal., Eur J Biochem 1997 Jun 1;246(2):425-32.
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Localized effects of cAMP mediated by distinct routes of protein kinase A.	Tasken K and Aandahl EM, Physiol Rev. 2004 Jan;84(1):137-67.

Additional References at PubMed

PMID:12475942

Genomics

Comparative Map Data

Akap14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	121,261,195 - 121,276,376 (-)	NCBI		GRCr8
mRatBN7.2	X	116,395,512 - 116,410,697 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	116,395,516 - 116,410,697 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	118,499,111 - 118,514,245 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	122,068,246 - 122,083,383 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	119,614,305 - 119,629,441 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	123,773,430 - 123,788,898 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	123,773,430 - 123,788,898 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	123,909,957 - 123,925,151 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	7,744,305 - 7,759,380 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	7,749,860 - 7,764,934 (+)	NCBI
Celera	X	115,623,134 - 115,638,227 (-)	NCBI		Celera
Cytogenetic Map	X	q35	NCBI

AKAP14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	119,895,893 - 119,920,716 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	119,895,837 - 119,920,716 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	119,029,856 - 119,054,679 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	118,913,964 - 118,938,707 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	118,811,817 - 118,836,559	NCBI
Celera	X	119,484,561 - 119,509,308 (+)	NCBI		Celera
Cytogenetic Map	X	q24	NCBI
HuRef	X	108,526,427 - 108,532,714 (+)	NCBI		HuRef
CHM1_1	X	118,940,982 - 118,965,708 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	118,271,014 - 118,295,842 (+)	NCBI		T2T-CHM13v2.0

Akap14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	36,414,351 - 36,432,495 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	36,414,351 - 36,432,495 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	37,150,698 - 37,168,842 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	37,150,698 - 37,168,842 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	34,690,693 - 34,708,837 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	33,582,143 - 33,600,287 (-)	NCBI		MGSCv36	mm8
Celera	X	23,874,320 - 23,892,464 (-)	NCBI		Celera
Cytogenetic Map	X	A3.3	NCBI
cM Map	X	21.57	NCBI

Akap14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955534	120,603 - 137,227 (-)	NCBI	ChiLan1.0	ChiLan1.0

AKAP14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	119,302,536 - 119,332,966 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	119,306,633 - 119,332,104 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	108,940,756 - 108,984,227 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	119,355,712 - 119,380,449 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	119,355,712 - 119,380,449 (+)	Ensembl	panpan1.1		panPan2

AKAP14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	91,900,154 - 91,927,629 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	77,974,562 - 77,995,029 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	93,638,719 - 93,659,194 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	93,637,986 - 93,659,085 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	91,091,653 - 91,112,118 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	92,851,191 - 92,871,607 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	92,580,095 - 92,600,580 (+)	NCBI		UU_Cfam_GSD_1.0

Akap14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	90,931,967 - 90,945,924 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936479	10,051,669 - 10,055,518 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AKAP14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	X	98,234,469 - 98,255,396 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	113,359,466 - 113,377,230 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AKAP14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666065	32,682,764 - 32,711,235 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Akap14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624895	3,829,155 - 3,834,955 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Akap14
71 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	63
Count of miRNA genes:	60
Interacting mature miRNAs:	61
Transcripts:	ENSRNOT00000009123
Prediction methods:	Microtar, Miranda, Pita, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598872	Memor14	Memory QTL 14	4.5		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	93956491	138956491	Rat
1598856	Memor1	Memory QTL 1	1.9		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	X	103312877	148312877	Rat
1598809	Memor15	Memory QTL 15	4.4		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	103312877	148312877	Rat
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	100567703	150256146	Rat
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
738029	Stresp2	Stress response QTL 2	3.4	0.0004	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	112934952	138400867	Rat
61431	Cia19	Collagen induced arthritis QTL 19	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	65612192	120568734	Rat
5685004	Bss104	Bone structure and strength QTL 104	3.9		tibia area (VT:1000281)	tibia area measurement (CMO:0001382)	X	113805422	126975220	Rat
10059603	Bw174	Body weight QTL 174	3.4	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	X	113937816	152453651	Rat
724551	Glom1	Glomerulus QTL 1	2.8	0.0004	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	X	75294106	120294106	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat

Markers in Region

AI044873

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	X	121,260,873 - 121,261,094 (+)	Marker Load Pipeline
mRatBN7.2	X	116,395,190 - 116,395,411 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	123,773,109 - 123,773,329	NCBI	Rnor6.0
Rnor_5.0	X	123,909,636 - 123,909,856	UniSTS	Rnor5.0
RGSC_v3.4	X	7,759,481 - 7,759,701	UniSTS	RGSC3.4
Celera	X	115,622,813 - 115,623,033	UniSTS
RH 3.4 Map	5	789.8	UniSTS
Cytogenetic Map	X	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	9	27	96	55	57	26	25	26	6	137	67	79	27	50	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_021703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039100002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC107580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ002474	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000009123 ⟹ ENSRNOP00000009123

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	116,395,516 - 116,410,697 (-)	Ensembl
Rnor_6.0 Ensembl	X	123,773,430 - 123,788,898 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105076 ⟹ ENSRNOP00000095169

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	116,395,516 - 116,410,693 (-)	Ensembl

RefSeq Acc Id:

NM_021703 ⟹ NP_067735

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	121,261,195 - 121,276,376 (-)	NCBI
mRatBN7.2	X	116,395,512 - 116,410,697 (-)	NCBI
Rnor_6.0	X	123,773,430 - 123,788,898 (-)	NCBI
Rnor_5.0	X	123,909,957 - 123,925,151 (-)	NCBI
RGSC_v3.4	X	7,744,305 - 7,759,380 (+)	RGD
Celera	X	115,623,134 - 115,638,227 (-)	RGD

Sequence:

show sequence

TTGGTTTGTACAGCTTAGCTCTGATCCTGAGGTCAAATAGCAAAGGGGGCTGTCGTTCTCTCTC
CTCTCCATTTCCTTTCCTTCGCTGACAGAATGGCTGTCCATTGTTCAGACTGCCAACGTTGCTG
TGGCAGCACTTGTAAACATTCTCTTTAGGAACCTTGGGGCAGAGCCGCTGAGAGACTGCTAAAG
CTTCCTCTGCTACTCCTTCAAAGAACCTGCTCATTTAGGCAAAATAAAATGAATAACAAAAAAA
AGCCCCCAAACCAGAAGGCGAAGACTGTGGAGAACACTAGCACAGCCAAGGCAAAGAAACCGGA
GGCTCCAGAGCCCAAGAATGTTACAGAACCAAAAGATAGTAAGGCCGTGGAGGACCCAAAGAAG
TCTGTGACAAATCAGAAAGAGAAGAAAACGGTGACCATCATTGCAGACCCAAAGGACAAAAAGA
GTGTGACGGAACCAAAAGAAAAGAAGACTGTGACGATCTCAGATCCCAAAGACAAGAAACCTGT
GATAGAGAAAGACAAGAGGACGGTGACATTTGTGACAGACGTAAAAGACAAGAGGATTGTGACC
GACACAAAAGAAAACAGGATTGCATCAATAGACACAAAAGAAAAGGGTCCAGTAGTGCCAGAAG
TAAAAGAGAAGAAAGTGCAGCTAATAGATCCGAAAGAGAAGGTGGTTGCACCGGTTGCACCGGT
TGCGCCGGTTGCGCATGCTGCCCAGGTTCCTCATGCTGCCCAGGTTCCGCATGCTGTCCAGGTT
CCGCATGCTGTGCCGGTTGCGCATGCTGCGCCGGTTGCGCATACTGCCCAGGTTTCGCATGCTG
CGCCGGTTGCGCCTTCTCTGCCTGTTGTGCCACCTGCGCCGGTTGTGCCACTTGCGCCAGTTGT
GCCACCTGCGCCAGTTGCTCATACTGAACCGGTAGCACATGCTGTGCCGTTTGCGCCACCTGCG
CCGGTTGCGCCACCTGCGTCAGTTGCGCCACCTGTGCCAGATGCTCCAGTTGCGCTAGTTGCGC
CAGTTGCTCCACAAGTAAAACAGAAGATTCGGGTGTCGGAGGTGAAGCGGAAAAAGGAAGTGCC
ACCACGTGTGCCCCAGTTAAAGGAAATGAAGGTGGTGTTATTCACACCAGAGATAAAAGAAAAA
AAGGTTGTGTCTGAGATCAAAGAGAAGACACAAGTAATAGATGGAAAAGAGAAGTTAATTGTGC
CAGACGTAAAAGAGAAAAAGCCTGCAGTTGTAGAGAAAAAAGACGAGAGGATGAATGAGATAGC
TCGGACTGTAGTTGAGGGCGTACTGGCTGCTTCTGTTCAGTTTGTGGAAGAAGCCAGAAATCCC
ATCAAGAACATCAAGTGGCTCACTCATGGGGAATTCACGGCAGAAAAGGGTCGAAAACAAATTG
AAAAGTTTGTTTCAACATGGGAGTTTCAAAACCGCTGGGTGTACTATGCAGATTTTATAGAGAA
GAAAGACCTAATTCACTCCTTCCACTATATCTACCGGGTGCGCTGGAGTGCCCCCACTGCTGTG
AGACCCATGGCACGAGTCAGTGCCAACGCCTACTTCACCATCAAGTTCAACAAGAGCAAACCTG
CGGATATGCCTGTTGATGTCTCTTATATCTTTGAGAATTCAGAACTACTTCAAAGGCCAGGAAA
GATTCGATTTCGAGAACAATGGCTGAGGGACATTACTGAGACCAAACATATTTTGTTGGAGTCT
ATCCCTTTTAAAGTTGTCTGATTCCTGTGTTATGTTTGAGGATGTTTTACAACCGACATTAAAA
ATATGAAACAGCATATCAAATCACATAATATTTATTGAATAATAAACTCATGGCACATAAAAAA
AAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039100002 ⟹ XP_038955930

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	121,266,290 - 121,276,278 (-)	NCBI
mRatBN7.2	X	116,400,606 - 116,410,607 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_067735	(Get FASTA)	NCBI Sequence Viewer
	XP_038955930	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAA05485	(Get FASTA)	NCBI Sequence Viewer
	EDM10840	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000009123
	ENSRNOP00000009123.2
	ENSRNOP00000095169.1
GenBank Protein	O35817	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_067735 ⟸ NM_021703

- UniProtKB:

O35817 (UniProtKB/Swiss-Prot), A6JMH8 (UniProtKB/TrEMBL), A0A8I6ANA3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNNKKKPPNQKAKTVENTSTAKAKKPEAPEPKNVTEPKDSKAVEDPKKSVTNQKEKKTVTIIAD
PKDKKSVTEPKEKKTVTISDPKDKKPVIEKDKRTVTFVTDVKDKRIVTDTKENRIASIDTKEKG
PVVPEVKEKKVQLIDPKEKVVAPVAPVAPVAHAAQVPHAAQVPHAVQVPHAVPVAHAAPVAHTA
QVSHAAPVAPSLPVVPPAPVVPLAPVVPPAPVAHTEPVAHAVPFAPPAPVAPPASVAPPVPDAP
VALVAPVAPQVKQKIRVSEVKRKKEVPPRVPQLKEMKVVLFTPEIKEKKVVSEIKEKTQVIDGK
EKLIVPDVKEKKPAVVEKKDERMNEIARTVVEGVLAASVQFVEEARNPIKNIKWLTHGEFTAEK
GRKQIEKFVSTWEFQNRWVYYADFIEKKDLIHSFHYIYRVRWSAPTAVRPMARVSANAYFTIKF
NKSKPADMPVDVSYIFENSELLQRPGKIRFREQWLRDITETKHILLESIPFKVV

hide sequence

Ensembl Acc Id:

ENSRNOP00000009123 ⟸ ENSRNOT00000009123

RefSeq Acc Id:	XP_038955930 ⟸ XM_039100002
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000095169 ⟸ ENSRNOT00000105076

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O35817-F1-model_v2	AlphaFold	O35817	1-502	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708510	AgrOrtholog
BioCyc Gene	G2FUF-1294	BioCyc
Ensembl Genes	ENSRNOG00000006899	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000009123	ENTREZGENE
	ENSRNOT00000009123.6	UniProtKB/Swiss-Prot
	ENSRNOT00000105076.1	UniProtKB/TrEMBL
InterPro	AKAP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	AKAP_28	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:60332	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	60332	ENTREZGENE
PANTHER	A-KINASE ANCHOR PROTEIN 14	UniProtKB/Swiss-Prot
	A-KINASE ANCHOR PROTEIN 14	UniProtKB/Swiss-Prot
	A-KINASE ANCHOR PROTEIN 14	UniProtKB/TrEMBL
	A-KINASE ANCHOR PROTEIN 14	UniProtKB/TrEMBL
Pfam	AKAP28	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Akap14	PhenoGen
RatGTEx	ENSRNOG00000006899	RatGTEx
UniProt	A0A8I6ANA3	ENTREZGENE, UniProtKB/TrEMBL
	A6JMH8	ENTREZGENE, UniProtKB/TrEMBL
	AKA14_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-25	Akap14	A-kinase anchoring protein 14	Akap14	A kinase (PRKA) anchor protein 14	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-08	Akap14	A kinase (PRKA) anchor protein 14	LOC60332	Testis-specific A-kinase-anchoring-protein	Symbol and Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

RGD Manual Annotations