LOC259246 (alpha-2u globulin PGCL1) - Rat Genome Database

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Gene: LOC259246 (alpha-2u globulin PGCL1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: LOC259246
Name: alpha-2u globulin PGCL1
RGD ID: 708506
Description: Predicted to enable insulin receptor activity and pheromone binding activity. Predicted to be involved in several processes, including locomotor rhythm; mitochondrion morphogenesis; and negative regulation of biosynthetic process. Located in extracellular space.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: allergen n I; allergen Rat n I; alpha(2)-euglobulin; alpha-2u-globulin; major urinary protein; MGC112596; MGC124936; Mup
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2 Ensembl575,142,157 - 75,564,845 (-)Ensembl
Rnor_6.0 Ensembl577,430,401 - 77,433,847 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl577,338,853 - 77,342,299 (-)EnsemblRnor6.0rn6Rnor6.0
RGSC_v3.4578,707,324 - 78,710,745 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1578,712,436 - 78,715,858 (-)NCBI
Cytogenetic Map5 NCBI


References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Length polymorphism in the 3' noncoding region of rat hepatic alpha 2u-globulin mRNAs. Ichiyoshi Y, etal., Biochim Biophys Acta 1987 Oct 9;910(1):43-51.
3. Male urinary protein-1 (Mup-1) expression in the female rat. Kondo Y and Yamada J, J Hered. 1983 Jul-Aug;74(4):280-2.
4. GOA pipeline RGD automated data pipeline
5. Molecular evidence of complex tissue- and sex-specific mRNA expression of the rat alpha(2u)-globulin multigene family. Saito K, etal., Biochem Biophys Res Commun 2000 Jun 7;272(2):337-44.
6. Cloning and sequence of several alpha 2u-globulin cDNAs. Unterman RD, etal., Proc Natl Acad Sci U S A 1981 Jun;78(6):3478-82.
Additional References at PubMed
PMID:1279439   PMID:2005132   PMID:2418834   PMID:2439333   PMID:2447393   PMID:2468522   PMID:6163771   PMID:6183262   PMID:8645715   PMID:12477932   PMID:15489334   PMID:25797582  


Genomics


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000076906   ⟹   ENSRNOP00000068371
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl577,430,401 - 77,433,847 (-)Ensembl
RefSeq Acc Id: NM_147214
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
RGSC_v3.4578,707,324 - 78,710,745 (-)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: ENSRNOP00000068371   ⟸   ENSRNOT00000076906

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P02761-F1-model_v2 AlphaFold P02761 1-181 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708506 AgrOrtholog
Ensembl Genes ENSRNOG00000042543 Ensembl
  ENSRNOG00000046529 Ensembl
  ENSRNOG00000067602 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000012293.6 UniProtKB/TrEMBL
  ENSRNOP00000056082.5 UniProtKB/TrEMBL
  ENSRNOP00000067018.3 UniProtKB/TrEMBL
  ENSRNOP00000067914.2 UniProtKB/TrEMBL
  ENSRNOP00000068285.2 UniProtKB/TrEMBL
  ENSRNOP00000080129 UniProtKB/Swiss-Prot
  ENSRNOP00000084655.1 UniProtKB/TrEMBL
  ENSRNOP00000088900.1 UniProtKB/TrEMBL
  ENSRNOP00000092008 UniProtKB/Swiss-Prot
  ENSRNOP00000093267.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012293.5 UniProtKB/TrEMBL
  ENSRNOT00000059320.5 UniProtKB/TrEMBL
  ENSRNOT00000074349.3 UniProtKB/TrEMBL
  ENSRNOT00000076466.2 UniProtKB/TrEMBL
  ENSRNOT00000076791.3 UniProtKB/TrEMBL
  ENSRNOT00000094674.1 UniProtKB/TrEMBL
  ENSRNOT00000100434 UniProtKB/Swiss-Prot
  ENSRNOT00000106951.1 UniProtKB/TrEMBL
  ENSRNOT00000116257.1 UniProtKB/TrEMBL
  ENSRNOT00000120034 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.128.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7322607 IMAGE-MGC_LOAD
  IMAGE:7367233 IMAGE-MGC_LOAD
  IMAGE:7370970 IMAGE-MGC_LOAD
InterPro Calycin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipocalin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipocalin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipocln_cytosolic_FA-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Maj_urinary UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:108577 IMAGE-MGC_LOAD
  MGC:112596 IMAGE-MGC_LOAD
  MGC:124936 IMAGE-MGC_LOAD
NCBI Gene 259246 ENTREZGENE
PANTHER PTHR11430 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Lipocalin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen LOC259246 PhenoGen
PRINTS MAJORURINARY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE LIPOCALIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50814 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A096MIX6_RAT UniProtKB/TrEMBL
  A0A096MJW3_RAT UniProtKB/TrEMBL
  A0A8I5ZYK0_RAT UniProtKB/TrEMBL
  A0A8I6A7F8_RAT UniProtKB/TrEMBL
  A0A8I6AJN1_RAT UniProtKB/TrEMBL
  F1LQM1_RAT UniProtKB/TrEMBL
  F7ET54_RAT UniProtKB/TrEMBL
  M0RBS2_RAT UniProtKB/TrEMBL
  MUP_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q54AE7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-09-23 LOC259246  alpha-2u globulin PGCL1      Symbol and Name status set to provisional 70820 PROVISIONAL