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Gene: Myo1a (myosin IA) Mus musculus
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Symbol: Myo1a
Name: myosin IA
RGD ID: 70079
Description: Exhibits actin filament binding activity. Involved in microvillus assembly. Localizes to several cellular components, including basal plasma membrane; brush border; and lateral plasma membrane. Is expressed in several structures, including inner ear and intestine. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 48 and sensorineural hearing loss. Orthologous to human MYO1A (myosin IA); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BBM-; BBM-I; BBMI; brush border myosin 1; brush border myosin I; MIHC; Myh; Myhl; myosin I heavy chain; myosin, heavy polypeptide-like (110kD); myosin-Ia; unconventional myosin-Ia
Orthologs:
Homo sapiens (human) : MYO1A (myosin IA)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myo1a (myosin IA)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myo1a (myosin IA)
Pan paniscus (bonobo/pygmy chimpanzee) : MYO1A (myosin IA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myo1a (myosin IA)
Sus scrofa (pig) : MYO1A (myosin IA)
Chlorocebus sabaeus (African green monkey) : MYO1A (myosin IA)
Heterocephalus glaber (naked mole-rat) : Myo1a (myosin IA)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl10127,705,170 - 127,720,940 (+)EnsemblGRCm38mm10GRCm38
GRCm3810127,703,436 - 127,720,940 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710127,142,312 - 127,157,996 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610127,108,205 - 127,123,887 (+)NCBImm8
MGSCv3610128,360,172 - 128,375,679 (+)NCBImm8
Celera10130,095,595 - 130,115,507 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.62NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Myo1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70079
Created: 2002-01-22
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.